3-Chloro-2-fluorobenzoyl chloride

Basic Information

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CAS Number

85345-76-2

Molecular Formula

C7H3Cl2FO

Molecular Weight

193 g/mol

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Carboxylic Acids

Fine Chemicals Dyes and Pigments Organic Dyes

Fine Chemicals Specialty Chemicals UV Stabilizers

Agricultural Chemicals Pesticides Herbicides

Electronic Chemicals Semiconductor Materials Etchants

Basic Physical Properties

Boiling Point

202-203 °C

Density

1.451 g/mL at 25 °C

Refractive Index

n20/D 1.5370(lit.)

SMILES

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ClC(=O)c1cccc(c1F)Cl

InChI

InChI=1S/C7H3Cl2FO/c8-5-3-1-2-4(6(5)10)7(9)11/h1-3H

InChIKey

VBYJOUAMJITBNL-UHFFFAOYSA-N

LogP

2.8581000000000003

Topological Polar Surface Area

17.07 Å²

Hydrogen Bond Donor/Acceptor

0 / 1

Complexity

163

Safety Information

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Hazard Statement

H226 Flammable liquid and vapor
Flammable liquids

H314 Causes severe skin burns and eye damage
Skin corrosion/irritation

Hazard Class

Class 8 Class 8

Sensitiveness

Moisture Sensitive

Synonyms & References

English

3-Chloro-2-fluorobenzoyl chloride

MDL Number

MFCD01631548

Customs Code

2916399090

FAQ

What regulatory guidelines apply to 3-Chloro-2-fluorobenzoyl chloride (CAS: 85345-76-2)?

3-Chloro-2-fluorobenzoyl chloride (CAS: 85345-76-2) is regulated under the Globally Harmonized System of Classification and Labelling of Chemicals (GHS) for its hazardous properties. It is subject to the REACH regulations in the European Union, which require manufacturers and importers to register substances above a certain tonnage. Additionally, the FDA and EPA in the U.S. may require specific handling, storage, and disposal practices based on its classification as a hazardous chemical.

Are there alternatives to 3-Chloro-2-fluorobenzoyl chloride (CAS: 85345-76-2) in synthesis?

While 3-Chloro-2-fluorobenzoyl chloride (CAS: 85345-76-2) is a versatile reagent, several alternatives can be used depending on the specific synthesis requirements. For example, 4-chlorobenzoyl chloride and 2-fluorobenzoyl chloride can be used as substitutes. Additionally, reactions using benzoic acid derivatives can offer similar functionalities with potentially safer handling conditions.

What is the market or research trend for 3-Chloro-2-fluorobenzoyl chloride (CAS: 85345-76-2)?

The market for 3-Chloro-2-fluorobenzoyl chloride (CAS: 85345-76-2) is driven by its use in pharmaceutical and agrochemical industries. Research trends are focusing on developing more sustainable and environmentally friendly synthesis methods. Recent studies are exploring the use of bio-based precursors and catalytic processes to reduce the reliance on hazardous reagents like 3-Chloro-2-fluorobenzoyl chloride.

How should waste containing 3-Chloro-2-fluorobenzoyl chloride (CAS: 85345-76-2) be handled?

Waste containing 3-Chloro-2-fluorobenzoyl chloride (CAS: 85345-76-2) should be collected in appropriate containers and disposed of through professional waste disposal services. Environmental protection measures include neutralizing acidic or basic residues before disposal. Incineration is often the preferred method, provided it is conducted in an environmentally controlled facility to prevent the release of harmful gases. Compliance with local and national regulations is essential for safe waste management.