2-(2-(Piperazin-1-yl)ethoxy)-ethanol dihydrochloride

Basic Information

View in Editor

CAS Number

85293-16-9

Molecular Formula

C8H20Cl2N2O2

Molecular Weight

247.17 g/mol

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Ethers

Basic Chemical Raw Materials Organic Chemicals Heterocyclic Compounds

Pharmaceutical Chemicals Pharmaceutical Intermediates Heterocyclic Intermediates

Basic Physical Properties

SMILES

View in Editor

C1CN(CCN1)CCOCCO.Cl.Cl

InChI

InChI=1S/C8H18N2O2.2ClH/c11-6-8-12-7-5-10-3-1-9-2-4-10;;/h9,11H,1-8H2;2*1H

InChIKey

JCYZKOJFYMJJTJ-UHFFFAOYSA-N

LogP

-0.2559000000000005

Topological Polar Surface Area

44.730000000000004 Å²

Hydrogen Bond Donor/Acceptor

2 / 4

Complexity

105

Synonyms & References

English

UNII-CVH693Z5FP
1-[2(2-Hydroxyethoxy)ethyl]piperazine dihydrochloride
2-[2-(piperazin-1-yl)ethoxy]ethanol dihydrochloride
FT-0655135
CVH693Z5FP
2-(2-(Piperazin-1-yl)ethoxy)-ethanol dihydrochloride
85293-16-9
2-(2-(Piperazin-1-yl)ethoxy)ethanoldihydrochloride
2-(2-piperazin-1-ylethoxy)ethanol;dihydrochloride
AC-26313
AM20110223
A25086
ETHANOL, 2-(2-(1-PIPERAZINYL)ETHOXY)-, DIHYDROCHLORIDE
2-[2-(piperazin-1-yl)ethoxy]ethan-1-ol dihydrochloride
EINECS 286-638-2
2-(2-(Piperazin-1-yl)ethoxy)ethanol dihydrochloride
2-(2-(Piperazin-1-yl)ethoxy)ethanol HCl
AKOS015897889
DTXSID50234494
SCHEMBL4752557
NS00092574
1-[2-(2-Hydroxyethoxy) ethyl] piperazine dihydrochloride
W-104087
1-[2-(2-Hydroxyethoxy)ethyl]piperazine dihydrochloride
2-(2-piperazin-1-ylethoxy)ethanol,dihydrochloride
Ethanol, 2-[2-(1-piperazinyl)ethoxy]-, dihydrochloride

MDL Number

MFCD07782127

Customs Code

2933599090

FAQ

What are the physical and chemical properties of 2-(2-(Piperazin-1-yl)ethoxy)-ethanol dihydrochloride (CAS: 85293-16-9)?

2-(2-(Piperazin-1-yl)ethoxy)-ethanol dihydrochloride (CAS: 85293-16-9) is a white crystalline solid with a molecular weight of approximately 308.82 g/mol. It is highly soluble in water and ethanol but less soluble in organic solvents. This compound exhibits low reactivity in neutral and basic media, making it suitable for use in various chemical reactions. It has a pKa of around 4.5, indicating its basic nature.

How is 2-(2-(Piperazin-1-yl)ethoxy)-ethanol dihydrochloride (CAS: 85293-16-9) typically synthesized?

2-(2-(Piperazin-1-yl)ethoxy)-ethanol dihydrochloride (CAS: 85293-16-9) is typically synthesized via the reaction of 2-(2-chloroethoxy)-ethanol with piperazine in the presence of a base such as sodium hydroxide. The reaction proceeds under mild conditions, and the yield can be up to 90%. The use of a suitable catalyst can improve the selectivity and efficiency of the reaction.

What industries use 2-(2-(Piperazin-1-yl)ethoxy)-ethanol dihydrochloride (CAS: 85293-16-9)?

2-(2-(Piperazin-1-yl)ethoxy)-ethanol dihydrochloride (CAS: 85293-16-9) is used in the pharmaceutical industry for the synthesis of various drugs due to its basic properties. It is also applied in the polymer industry for the modification of polymer properties and in the semiconductor industry for use in chemical vapor deposition processes. Additionally, it has potential applications in sensor technology for the detection of specific chemicals.

What precautions should be taken when handling 2-(2-(Piperazin-1-yl)ethoxy)-ethanol dihydrochloride (CAS: 85293-16-9)?

When handling 2-(2-(Piperazin-1-yl)ethoxy)-ethanol dihydrochloride (CAS: 85293-16-9), it is essential to wear appropriate personal protective equipment (PPE) including gloves, goggles, and a lab coat. This compound should be handled in a well-ventilated area or a fume hood to avoid inhalation. Spills should be cleaned up using appropriate absorbent materials, and the area should be thoroughly rinsed with water. Always consult the Safety Data Sheet (SDS) for detailed emergency procedures and storage recommendations.