Compound Q&A

How is 2-(2-(Piperazin-1-yl)ethoxy)-ethanol dihydrochloride (CAS: 85293-16-9) typically synthesized?

Answer

2-(2-(Piperazin-1-yl)ethoxy)-ethanol dihydrochloride
2-(2-(Piperazin-1-yl)ethoxy)-ethanol dihydrochloride (CAS: 85293-16-9) is typically synthesized via the reaction of 2-(2-chloroethoxy)-ethanol with piperazine in the presence of a base such as sodium hydroxide. The reaction proceeds under mild conditions, and the yield can be up to 90%. The use of a suitable catalyst can improve the selectivity and efficiency of the reaction.

About

CAS No 85293-16-9
English Name 2-(2-(Piperazin-1-yl)ethoxy)-ethanol dihydrochloride
Molecular Formula C8H20Cl2N2O2
Molecular Weight 247.17 g/mol
SMILES C1CN(CCN1)CCOCCO.Cl.Cl
InChIKey JCYZKOJFYMJJTJ-UHFFFAOYSA-N
Last Updated: 2025-10-19 20:30

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