Abt-737 | CAS No. 852808-04-9

Abt-737

Basic Information

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CAS Number

852808-04-9

Molecular Formula

C42H45ClN6O5S2

Molecular Weight

813.43 g/mol

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Carboxylic Acids

Basic Chemical Raw Materials Organic Chemicals Heterocyclic Compounds

Pharmaceutical Chemicals Pharmaceutical Intermediates Heterocyclic Intermediates

Fine Chemicals Dyes and Pigments Organic Dyes

Fine Chemicals Surfactants Anionic Surfactants

Agricultural Chemicals Pesticides Herbicides

Laboratory Chemicals Research Chemicals Biochemical Reagents

Basic Physical Properties

Melting Point

152-154°C

SMILES

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CN(CCC(Nc1ccc(cc1[N+](=O)[O-])S(=O)(=O)NC(=O)c1ccc(cc1)N1CCN(CC1)Cc1ccccc1c1ccc(cc1)Cl)CSc1ccccc1)C

InChI

1S/C42H45ClN6O5S2/c1-46(2)23-22-35(30-55-37-9-4-3-5-10-37)44-40-21-20-38(28-41(40)49(51)52)56(53,54)45-42(50)32-14-18-36(19-15-32)48-26-24-47(25-27-48)29-33-8-6-7-11-39(33)31-12-16-34(43)17-13-31/h3-21,28,35,44H,22-27,29-30H2,1-2H3,(H,45,50)/t35-/m1/s1

InChIKey

HPLNQCPCUACXLM-PGUFJCEWSA-N

LogP

9.95140

Complexity

1320

Safety Information

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Hazard Statement

H302 Harmful if swallowed
Acute toxicity, oral

H315 Causes skin irritation
Skin corrosion/irritation

H319 Causes serious eye irritation
Serious eye damage/eye irritation

H335 May cause respiratory irritation
Specific target organ toxicity, single exposure; Respiratory tract irritation

Synonyms & References

English

ABT-737
4-[4-[(4'-Chloro[1,1'-biphenyl]-2-yl)methyl]-1-piperazinyl]-N-[[4-[[(1R)-3-(dimethylamino)-1-[(phenylthio)methyl]propyl]amino]-3-nitrophenyl]sulfonyl]benzamide
ABT 737
4-[4-[[2-(4-chlorophenyl)phenyl]methyl]piperazin-1-yl]-N-[4-[[(2R)-4-(dimethylamino)-1-phenylsulfanylbutan-2-yl]amino]-3-nitrophenyl]sulfonylbenzamide
ABT-737 (ABT 737, ABT737 )
ABT-737 BCL-2 KINASE INHIBITOR
Benzamide, 4-[4-[(4'-chloro[1,1'-biphenyl]-2-yl)methyl]-1-piperazinyl]-N-[[4-[[(1R)-3-(dimethy...
ABT737
Z5NFR173NV
C42H45ClN6O5S2
4-{4-[(4'-Chlorobiphenyl-2-Yl)methyl]piperazin-1-Yl}-N-{[4-({(1r)-3-(Dimethylamino)-1-[(Phenylthio)methyl]propyl}amino)-3-Nitrophenyl]sulfonyl}benzamide
4-{4-[(4'-chlorobiphenyl-2-yl)methyl]piperazin-1-yl}-N-{[4-({(1R)-3-(dimethylamino)-1-[(phenylsul

MDL Number

MFCD12756212

FAQ

What is Abt-737 (CAS: 852808-04-9)?

Abt-737 (CAS: 852808-04-9) is a chemical compound primarily used in research. It is known for its potential as a cyclin-dependent kinase inhibitor, which makes it valuable in studying cell cycle regulation and cancer research.

What are the main uses of Abt-737 (CAS: 852808-04-9)?

Abt-737 (CAS: 852808-04-9) is mainly used in research settings, particularly in studies related to cell cycle regulation and as a potential anticancer agent. It is also used in pharmacological studies targeting cyclin-dependent kinases.

Is Abt-737 (CAS: 852808-04-9) safe?

Abt-737 (CAS: 852808-04-9) is considered safe when handled properly. However, it should be used under appropriate safety precautions, including appropriate ventilation and wearing appropriate personal protective equipment (PPE). It is not for ingestion and should be stored away from sources of heat and light.

How should Abt-737 (CAS: 852808-04-9) be stored?

Abt-737 (CAS: 852808-04-9) should be stored in a cool, dry place, away from direct sunlight and heat sources. It should be kept in a tightly sealed container to prevent degradation. The storage area should be well-ventilated and accessible only to authorized personnel.