![N-[(3S)-1-(Dimethylcarbamoyl)-3-pyrrolidinyl]-5-[(Z)-(5-fluoro-2-oxo-1,2-dihydro-3H-indol-3-ylidene)methyl]-2,4-dimethyl-1H-pyrrole-3-carboxamide structure](https://static.chemtradehub.com/structs/101/1013920-15-4-a4c8.webp "N-[(3S)-1-(Dimethylcarbamoyl)-3-pyrrolidinyl]-5-[(Z)-(5-fluoro-2-oxo-1,2-dihydro-3H-indol-3-ylidene)methyl]-2,4-dimethyl-1H-pyrrole-3-carboxamide structure")
N-[(3S)-1-(Dimethylcarbamoyl)-3-pyrrolidinyl]-5-[(Z)-(5-fluoro-2-oxo-1,2-dihydro-3H-indol-3-ylidene)methyl]-2,4-dimethyl-1H-pyrrole-3-carboxamide
CAS Number:
1013920-15-4
Molecular Formula:
C23H26FN5O3
2,2,2-Trifluoro-1-(4-fluorophenyl)ethanamine | CAS No. 852443-99-3
2,2,2-Trifluoro-1-(4-fluorophenyl)ethanamine
Basic Information
CAS Number
852443-99-3
Molecular Formula
C8H7F4N
Molecular Weight
193.14 g/mol
AD
Basic Physical Properties
Boiling Point
198.7±40.0 °C at 760 mmHg
Density
1.3±0.1 g/cm3
Flash Point
87.6±19.2 °C
Vapor Pressure
0.4±0.4 mmHg at 25°C
Synonyms & References
English
- MFCD07374560
- AB39792
- AB39793
- FRDAKAYQSQLWRW-UHFFFAOYSA-N
- DTXSID60640789
- AB39796
- 2,2,2-Trifluoro-1-(4-fluoro-phenyl)-ethylamine, AldrichCPR
- FT-0691295
- 852443-99-3
- AMY7136
- 2,2,2-Trifluoro-1-(4-fluorophenyl)ethanamine
- 2,2,2-Trifluoro-1-(4-fluoro-phenyl)-ethylamine
- AKOS016844147
- EN300-70591
- A863636
- 1-(4-Fluorophenyl)-2,2,2-trifluoroethanamine
- 2,2,2-TRIFLUORO-1-(4-FLUOROPHENYL)ETHAN-1-AMINE
- FT-0690241
- (1R)-2,2,2-TRIFLUORO-1-(4-FLUOROPHENYL)ETHYLAMINE
- AKOS000174693
- SCHEMBL296872
MDL Number
MFCD07374560
FAQ
What are the physical and chemical properties of 2,2,2-Trifluoro-1-(4-fluorophenyl)ethanamine (CAS: 852443-99-3)?
2,2,2-Trifluoro-1-(4-fluorophenyl)ethanamine is a colorless to white crystalline solid with a molecular weight of approximately 251.11 g/mol. This compound has low water solubility and is soluble in organic solvents like methanol and ethanol. It is moderately reactive and can undergo nucleophilic substitution and electrophilic aromatic substitution reactions.
How is 2,2,2-Trifluoro-1-(4-fluorophenyl)ethanamine (CAS: 852443-99-3) typically synthesized?
2,2,2-Trifluoro-1-(4-fluorophenyl)ethanamine can be synthesized via a multi-step process involving fluorination and amination reactions. Commonly, 4-fluorophenyl trifluoromethyl ketone is reacted with a suitable amine in the presence of a catalyst to yield the target compound with high selectivity and yield.
What industries use 2,2,2-Trifluoro-1-(4-fluorophenyl)ethanamine (CAS: 852443-99-3)?
2,2,2-Trifluoro-1-(4-fluorophenyl)ethanamine is primarily used in the pharmaceutical industry as an intermediate in the synthesis of drug candidates. It also finds applications in the polymer industry for the development of novel materials with enhanced properties. This compound is also relevant in the production of sensors and semiconductors due to its unique chemical characteristics.
What precautions should be taken when handling 2,2,2-Trifluoro-1-(4-fluorophenyl)ethanamine (CAS: 852443-99-3)?
When handling 2,2,2-Trifluoro-1-(4-fluorophenyl)ethanamine, it is crucial to wear appropriate personal protective equipment (PPE) including gloves, goggles, and a lab coat. Ensure adequate ventilation by using a fume hood during handling. Spills should be managed using appropriate absorbents, and the area should be cleaned thoroughly. Always refer to the Safety Data Sheet (SDS) for detailed guidelines on handling and storage.
Related Compounds
![7-Methylpyrazolo[1,5-a]pyrimidine-3-carboxylic acid structure](https://static.chemtradehub.com/structs/101/1016505-59-1-4c54.webp "7-Methylpyrazolo[1,5-a]pyrimidine-3-carboxylic acid structure")
7-Methylpyrazolo[1,5-a]pyrimidine-3-carboxylic acid
CAS Number:
1016505-59-1
Molecular Formula:
C8H7N3O2
![2-Fluoro-6-({[(2-methyl-2-propanyl)oxy]carbonyl}amino)benzoic acid structure](https://static.chemtradehub.com/structs/104/1048919-15-8-ba81.webp "2-Fluoro-6-({[(2-methyl-2-propanyl)oxy]carbonyl}amino)benzoic acid structure")
2-Fluoro-6-({[(2-methyl-2-propanyl)oxy]carbonyl}amino)benzoic acid
CAS Number:
1048919-15-8
Molecular Formula:
C12H14FNO4
1,5,8-Trihydroxy-3-methoxy-2-(3-methyl-2-buten-1-yl)-9H-xanthen-9-one
CAS Number:
110187-11-6
Molecular Formula:
C19H18O6
![9-Benzyl-2,9-diazaspiro[5.5]undecane dihydrochloride structure](https://static.chemtradehub.com/structs/119/1198286-24-6-4781.webp "9-Benzyl-2,9-diazaspiro[5.5]undecane dihydrochloride structure")
9-Benzyl-2,9-diazaspiro[5.5]undecane dihydrochloride
CAS Number:
1198286-24-6
Molecular Formula:
C16H26Cl2N2
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