Compound Q&A

How is 2,2,2-Trifluoro-1-(4-fluorophenyl)ethanamine (CAS: 852443-99-3) typically synthesized?

Answer

2,2,2-Trifluoro-1-(4-fluorophenyl)ethanamine
2,2,2-Trifluoro-1-(4-fluorophenyl)ethanamine can be synthesized via a multi-step process involving fluorination and amination reactions. Commonly, 4-fluorophenyl trifluoromethyl ketone is reacted with a suitable amine in the presence of a catalyst to yield the target compound with high selectivity and yield.

About

English Name 2,2,2-Trifluoro-1-(4-fluorophenyl)ethanamine
Molecular Formula C8H7F4N
Molecular Weight 193.14 g/mol
SMILES C1=CC(=CC=C1C(C(F)(F)F)N)F
InChIKey FRDAKAYQSQLWRW-UHFFFAOYSA-N
Last Updated: 2026-03-16 13:10

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