7-Bromotryptophan

Basic Information

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CAS Number

852391-45-8

Molecular Formula

C11H11BrN2O2

Molecular Weight

283.13 g/mol

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Carboxylic Acids

Basic Chemical Raw Materials Organic Chemicals Amines

Basic Chemical Raw Materials Organic Chemicals Heterocyclic Compounds

Pharmaceutical Chemicals Pharmaceutical Intermediates Heterocyclic Intermediates

Fine Chemicals Dyes and Pigments Organic Dyes

Fine Chemicals Surfactants Anionic Surfactants

Agricultural Chemicals Pesticides Herbicides

Basic Physical Properties

Density

1.704

SMILES

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NC(CC1=CNC2=C(Br)C=CC=C12)C(O)=O

InChI

InChI=1S/C11H11BrN2O2/c12-8-3-1-2-7-6(5-14-10(7)8)4-9(13)11(15)16/h1-3,5,9,14H,4,13H2,(H,15,16)

InChIKey

VMMOOBBCGTVDGP-UHFFFAOYSA-N

LogP

1.8848

Topological Polar Surface Area

79.11000000000001 Å²

Hydrogen Bond Donor/Acceptor

4 / 4

Complexity

275

Synonyms & References

English

Tryptophan, 7-bromo-
2-Amino-3-(7-bromo-1H-indol-3-yl)propanoic acid
7-BROMO-DL-TRYPTOPHAN
7-Bromo-L-Trytophan
(R)-2-Amino-3-(7-bromo-1H-indol-3-yl)propanoic acid
KM2304
6040AH
AK396384
391B458
2-Amino-3-(7-bromo-1H-indole-3-yl)propionic acid
(2S)-2-amino-3-(7-bromo-1H-indol-3-yl)propanoic Acid

MDL Number

MFCD04972047

FAQ

What are the physical and chemical properties of 7-Bromotryptophan (CAS: 852391-45-8)?

7-Bromotryptophan (CAS: 852391-45-8) is an odorless white to off-white crystalline powder. It has a molecular weight of approximately 279.03 g/mol and is poorly soluble in water but soluble in organic solvents like ethanol. It is highly reactive towards nucleophiles and exhibits good stability in neutral to slightly basic conditions.

How is 7-Bromotryptophan (CAS: 852391-45-8) typically synthesized?

7-Bromotryptophan (CAS: 852391-45-8) is typically synthesized through bromination of tryptophan using N-bromosuccinimide (NBS) as a brominating agent. The reaction is performed in an inert solvent like methylene chloride under light or UV radiation. The product shows high selectivity and good yield.

What industries use 7-Bromotryptophan (CAS: 852391-45-8)?

7-Bromotryptophan (CAS: 852391-45-8) is primarily used in the pharmaceutical industry for drug development. It is also employed in the synthesis of certain polymers and in the production of chiral compounds for applications in semiconductors and sensors.

What precautions should be taken when handling 7-Bromotryptophan (CAS: 852391-45-8)?

When handling 7-Bromotryptophan (CAS: 852391-45-8), proper personal protective equipment (PPE) such as gloves, goggles, and a lab coat is essential. Work should be conducted in a well-ventilated area or fume hood. Spills should be handled carefully to avoid skin contact and inhalation. Refer to the Safety Data Sheet (SDS) for detailed information on spill cleanup procedures and emergency response.