(5R)-5-[(7-Chloro-1H-indol-3-yl)methyl]-3-methyl-2,4-imidazolidinedione | CAS No. 852391-19-6

(5R)-5-[(7-Chloro-1H-indol-3-yl)methyl]-3-methyl-2,4-imidazolidinedione

Basic Information

CAS Number

852391-19-6

Molecular Formula

C13H12ClN3O2

Molecular Weight

277.71 g/mol

AD

Basic Physical Properties

O=C1N(C)C([C@@H](CC2=CNC3=C2C=CC=C3Cl)N1)=O

InChI

InChI=1S/C13H12ClN3O2/c1-17-12(18)10(16-13(17)19)5-7-6-15-11-8(7)3-2-4-9(11)14/h2-4,6,10,15H,5H2,1H3,(H,16,19)/t10-/m1/s1

InChIKey

WIKGAEMMNQTUGL-SNVBAGLBSA-N

LogP

1.9139999999999997

Topological Polar Surface Area

65.2 Ų

Hydrogen Bond Donor/Acceptor

2 / 5

Synonyms & References

English

  • 2,4-Imidazolidinedione, 5-[(7-chloro-1H-indol-3-yl)methyl]-3-methyl-, (5R)-
  • (5R)-5-[(7-Chloro-1H-indol-3-yl)methyl]-3-methyl-2,4-imidazolidin edione
  • Necrostatin 2

MDL Number

MFCD19443135

FAQ

What are the physical and chemical properties of (5R)-5-[(7-Chloro-1H-indol-3-yl)methyl]-3-methyl-2,4-imidazolidinedione (CAS: 852391-19-6)?

(5R)-5-[(7-Chloro-1H-indol-3-yl)methyl]-3-methyl-2,4-imidazolidinedione is a crystalline solid with a molecular weight of approximately 318.78 g/mol. It has a low solubility in water but is moderately soluble in common organic solvents like methanol and ethanol. This compound exhibits good reactivity towards nucleophiles and can undergo various chemical transformations. It is stable under normal conditions but should be stored in a dry place away from moisture and heat.

How is (5R)-5-[(7-Chloro-1H-indol-3-yl)methyl]-3-methyl-2,4-imidazolidinedione (CAS: 852391-19-6) typically synthesized?

(5R)-5-[(7-Chloro-1H-indol-3-yl)methyl]-3-methyl-2,4-imidazolidinedione can be synthesized via a multi-step process involving the coupling of 7-chloroindole and methyl imidazolidinone. The key steps include the condensation reaction, followed by the formation of the imidazolidinedione ring. The synthesis typically involves the use of a base and a catalyst to achieve high selectivity and yield. Detailed procedures and conditions can be found in the literature.

What industries use (5R)-5-[(7-Chloro-1H-indol-3-yl)methyl]-3-methyl-2,4-imidazolidinedione (CAS: 852391-19-6)?

(5R)-5-[(7-Chloro-1H-indol-3-yl)methyl]-3-methyl-2,4-imidazolidinedione finds applications in the pharmaceutical industry for its potential use as a ligand in metal complexes. It is also explored in the polymer industry for its ability to enhance the properties of certain polymers. Additionally, it has potential uses in the development of sensors and semiconductors due to its chemical structure and reactivity.

What precautions should be taken when handling (5R)-5-[(7-Chloro-1H-indol-3-yl)methyl]-3-methyl-2,4-imidazolidinedione (CAS: 852391-19-6)?

When handling (5R)-5-[(7-Chloro-1H-indol-3-yl)methyl]-3-methyl-2,4-imidazolidinedione, it is crucial to wear appropriate personal protective equipment (PPE) including gloves, goggles, and a lab coat. The compound should be stored in a cool, dry place away from sources of heat and moisture. In case of a spill, it should be cleaned up using personal protective equipment, ensuring the area is well-ventilated. Safety data sheets (SDS) should be consulted for detailed handling and disposal information.

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