4-[3-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl]morpholine

Basic Information

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CAS Number

852227-95-3

Molecular Formula

C16H24BNO3

Molecular Weight

289.18 g/mol

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Ethers

Basic Chemical Raw Materials Organic Chemicals Heterocyclic Compounds

Pharmaceutical Chemicals Pharmaceutical Intermediates Heterocyclic Intermediates

Basic Physical Properties

Physical State

No data available

Melting Point

82.0 to 87.0 deg-C

Boiling Point

431.5℃ at 760 mmHg

Flash Point

214.8±27.3 °C

SMILES

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CC1(C)OB(OC1(C)C)c2cccc(c2)N3CCOCC3

InChI

InChI=1S/C16H24BNO3/c1-15(2)16(3,4)21-17(20-15)13-6-5-7-14(12-13)18-8-10-19-11-9-18/h5-7,12H,8-11H2,1-4H3

InChIKey

NCJDKFFODGZRRL-UHFFFAOYSA-N

LogP

1.8224

Topological Polar Surface Area

30.930000000000003 Å²

Hydrogen Bond Donor/Acceptor

0 / 4

Complexity

353

Safety Information

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Hazard Statement

H315 Causes skin irritation
Skin corrosion/irritation

H319 Causes serious eye irritation
Serious eye damage/eye irritation

Synonyms & References

English

4-[3-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl]morpholine
3-Morpholinophenylboronic acid, pinacol ester
Morpholine,4-[3-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl]-
3-(4-Morpholino)phenylboronic acid pinacol ester
3-(morpholino)phenylboronic acid pinacol ester
3-hydroxy-2,3-dimethylbutan-2-yl hydrogen 3-morpholinophenylboronate
4-(3-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl)morpholine
2-[3-(Morpholino)phenyl]-4,4,5,5-tetramethyl-1,3,2-dioxaborolane
3-morpholinophenylboronic acid pinacol ester
PubChem19450
3-MORPHOLINOPHENYLBORONIC ACID PINACOL
KSC496K1F
K
3-(Morpholino)phenylboronic Acid Pinacol Ester

MDL Number

MFCD03412097

Customs Code

2934999090

FAQ

What is 4-[3-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl]morpholine (CAS: 852227-95-3)?

4-[3-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl]morpholine is a chemical compound with the CAS number 852227-95-3. It features a morpholine ring with a tetramethyl-1,3,2-dioxaborole group attached to a phenyl group. This compound is primarily used in medicinal chemistry, particularly in the synthesis of boron-containing drugs and in boronate ester-mediated reactions.

What are the main uses of 4-[3-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl]morpholine (CAS: 852227-95-3)?

4-[3-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl]morpholine is mainly used in the pharmaceutical industry for the synthesis of boron-containing drugs. It is also utilized in organic synthesis, particularly for boronate ester-mediated reactions, in academic and industrial research settings.

Is 4-[3-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl]morpholine (CAS: 852227-95-3) safe?

4-[3-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl]morpholine is generally considered safe when handled with appropriate precautions. It is important to follow safety guidelines, including wearing appropriate personal protective equipment (PPE) such as gloves and goggles. Ensure the compound is stored in a cool, dry place, away from sources of heat and direct sunlight.

How should 4-[3-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl]morpholine (CAS: 852227-95-3) be stored?

4-[3-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl]morpholine should be stored in a cool, dry place to prevent degradation. Store it in a tightly sealed container to protect it from moisture and light. The compound should be kept away from heat sources and direct sunlight. Follow all storage guidelines provided by the manufacturer to ensure safety and efficacy.