Seladelpar | CAS No. 851528-79-5

Seladelpar

Basic Information

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CAS Number

851528-79-5

Molecular Formula

C21H23F3O5S

Molecular Weight

444.47 g/mol

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Carboxylic Acids

Basic Chemical Raw Materials Organic Chemicals Ethers

Fine Chemicals Dyes and Pigments Organic Dyes

Fine Chemicals Surfactants Anionic Surfactants

Fine Chemicals Specialty Chemicals UV Stabilizers

Agricultural Chemicals Pesticides Herbicides

Basic Physical Properties

SMILES

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CCOC(COC1=CC=C(C=C1)C(F)(F)F)CSC2=CC(=C(C=C2)OCC(=O)O)C

InChI

InChI=1S/C21H23F3O5S/c1-3-27-17(11-28-16-6-4-15(5-7-16)21(22,23)24)13-30-18-8-9-19(14(2)10-18)29-12-20(25)26/h4-10,17H,3,11-13H2,1-2H3,(H,25,26)/t17-/m1/s1

InChIKey

JWHYSEDOYMYMNM-QGZVFWFLSA-N

LogP

5.0534200000000045

Topological Polar Surface Area

64.99000000000001 Å²

Hydrogen Bond Donor/Acceptor

1 / 5

Complexity

511

Safety Information

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Hazard Statement

H302 Harmful if swallowed
Acute toxicity, oral

H315 Causes skin irritation
Skin corrosion/irritation

H319 Causes serious eye irritation
Serious eye damage/eye irritation

H335 May cause respiratory irritation
Specific target organ toxicity, single exposure; Respiratory tract irritation

Synonyms & References

English

MBX 8025
Seladelpar
7C00L34NB9
(R)-2-(4-((2-ethoxy-3-(4-(trifluoromethyl)phenoxy)propyl)thio)-2-methylphenoxy)acetic acid
2-[4-[(2R)-2-ethoxy-3-[4-(trifluoromethyl)phenoxy]propyl]sulfanyl-2-methylphenoxy]acetic acid
MBX8025
Seladelpar [INN]
Seladelpar [USAN]
Seladelpar (USAN/INN)
Seladelpar [USAN:INN]
GTPL11137
BDBM50213714
DB12390
SB18935
compound 3r [PMID: 17524639]
Acetic acid, 2-(4-(((2R)-2-ethoxy-3-(4-(trifluoromethyl)phenoxy)propyl)thio)-2-methylphenoxy)-
851528-79-5 (free base)
UNII-7C00L34NB9
Seladelpar?
JWHYSEDOYMYMNM-QGZVFWFLSA-N
BS-17646
D11256
851528-79-5
(+)-MBX-8025
CHEMBL230158
MBX-8025
AKOS037649258
HY-19522
Livdelzi
BJB52879
KKB

MDL Number

MFCD28502443

FAQ

What is Seladelpar (CAS: 851528-79-5)?

Seladelpar (CAS: 851528-79-5) is a selective peroxisome proliferator-activated receptor-δ (PPAR-δ) agonist, used primarily in the treatment of pulmonary arterial hypertension (PAH). It is a white to off-white crystalline powder with a molecular formula of C23H28ClN2O2 and a molecular weight of 388.89.

What are the main uses of Seladelpar (CAS: 851528-79-5)?

Seladelpar (CAS: 851528-79-5) is mainly used for the treatment of pulmonary arterial hypertension (PAH) as an oral medication. It helps to improve exercise capacity and reduce symptoms associated with PAH, making it a valuable therapeutic option for patients suffering from this condition.

Is Seladelpar (CAS: 851528-79-5) safe?

Seladelpar (CAS: 851528-79-5) is generally considered safe when used as prescribed. However, it may cause side effects such as nausea, diarrhea, and liver enzyme elevations. Patients should be monitored regularly, and the medication should be used under the guidance of a healthcare provider to ensure safety.

How should Seladelpar (CAS: 851528-79-5) be stored?

Seladelpar (CAS: 851528-79-5) should be stored at room temperature (15°C to 30°C or 59°F to 86°F), away from moisture and direct sunlight. It should be kept in a tightly closed container to protect it from light and humidity. Avoid storing it in areas with high temperatures or humidity, as this may degrade the compound's efficacy and safety.