![N-[(3S)-1-(Dimethylcarbamoyl)-3-pyrrolidinyl]-5-[(Z)-(5-fluoro-2-oxo-1,2-dihydro-3H-indol-3-ylidene)methyl]-2,4-dimethyl-1H-pyrrole-3-carboxamide structure](https://static.chemtradehub.com/structs/101/1013920-15-4-a4c8.webp "N-[(3S)-1-(Dimethylcarbamoyl)-3-pyrrolidinyl]-5-[(Z)-(5-fluoro-2-oxo-1,2-dihydro-3H-indol-3-ylidene)methyl]-2,4-dimethyl-1H-pyrrole-3-carboxamide structure")
N-[(3S)-1-(Dimethylcarbamoyl)-3-pyrrolidinyl]-5-[(Z)-(5-fluoro-2-oxo-1,2-dihydro-3H-indol-3-ylidene)methyl]-2,4-dimethyl-1H-pyrrole-3-carboxamide
CAS Number:
1013920-15-4
Molecular Formula:
C23H26FN5O3
P-({[(2R)-1-(6-Amino-9H-purin-9-yl)-2-propanyl]oxy}methyl)-N-[(2S)-1-isopropoxy-1-oxo-2-propanyl]phosphonamidic acid | CAS No. 851456-00-3
P-({[(2R)-1-(6-Amino-9H-purin-9-yl)-2-propanyl]oxy}methyl)-N-[(2S)-1-isopropoxy-1-oxo-2-propanyl]phosphonamidic acid
Basic Information
CAS Number
851456-00-3
Molecular Formula
C15H25N6O5P
Molecular Weight
400.38 g/mol
AD
Chemical Classification
Basic Physical Properties
Synonyms & References
English
- Tenofovir Related Compound 4
- [(2R)-1-(6-Aminopurin-9-yl)propan-2-yl]oxymethyl-N-[(2S)-1-oxo-1-propan-2-yloxypropan-2-yl]phosphona
MDL Number
MFCD32068304
FAQ
What are the physical and chemical properties of P-({[(2R)-1-(6-Amino-9H-purin-9-yl)-2-propanyl]oxy}methyl)-N-[(2S)-1-isopropoxy-1-oxo-2-propanyl]phosphonamidic acid (CAS: 851456-00-3)?
P-({[(2R)-1-(6-Amino-9H-purin-9-yl)-2-propanyl]oxy}methyl)-N-[(2S)-1-isopropoxy-1-oxo-2-propanyl]phosphonamidic acid is a crystalline compound with a molecular weight of approximately 642.37 g/mol. It is soluble in water and organic solvents. The compound exhibits moderate reactivity, particularly towards nucleophilic substitution reactions.
How is P-({[(2R)-1-(6-Amino-9H-purin-9-yl)-2-propanyl]oxy}methyl)-N-[(2S)-1-isopropoxy-1-oxo-2-propanyl]phosphonamidic acid (CAS: 851456-00-3) typically synthesized?
P-({[(2R)-1-(6-Amino-9H-purin-9-yl)-2-propanyl]oxy}methyl)-N-[(2S)-1-isopropoxy-1-oxo-2-propanyl]phosphonamidic acid is synthesized via a multi-step process involving the protection of the amino group, phosphonation, and subsequent deprotection. Commonly used catalysts include various organometallic reagents, and the overall yield is around 70-80%.
What industries use P-({[(2R)-1-(6-Amino-9H-purin-9-yl)-2-propanyl]oxy}methyl)-N-[(2S)-1-isopropoxy-1-oxo-2-propanyl]phosphonamidic acid (CAS: 851456-00-3)?
P-({[(2R)-1-(6-Amino-9H-purin-9-yl)-2-propanyl]oxy}methyl)-N-[(2S)-1-isopropoxy-1-oxo-2-propanyl]phosphonamidic acid is primarily used in pharmaceuticals for developing new drugs. It may also have potential applications in the synthesis of polymers and as a reagent in analytical chemistry for sensor development and semiconductors.
What precautions should be taken when handling P-({[(2R)-1-(6-Amino-9H-purin-9-yl)-2-propanyl]oxy}methyl)-N-[(2S)-1-isopropoxy-1-oxo-2-propanyl]phosphonamidic acid (CAS: 851456-00-3)?
When handling P-({[(2R)-1-(6-Amino-9H-purin-9-yl)-2-propanyl]oxy}methyl)-N-[(2S)-1-isopropoxy-1-oxo-2-propanyl]phosphonamidic acid, proper personal protective equipment (PPE) should be used, including gloves, goggles, and a lab coat. Work should be conducted in a fume hood to avoid inhalation. In case of spill, neutralize the spill with an appropriate base and then clean up according to standard safety protocols. Always refer to the Safety Data Sheet (SDS) for detailed handling information.
Related Compounds
![7-Methylpyrazolo[1,5-a]pyrimidine-3-carboxylic acid structure](https://static.chemtradehub.com/structs/101/1016505-59-1-4c54.webp "7-Methylpyrazolo[1,5-a]pyrimidine-3-carboxylic acid structure")
7-Methylpyrazolo[1,5-a]pyrimidine-3-carboxylic acid
CAS Number:
1016505-59-1
Molecular Formula:
C8H7N3O2
![2-Fluoro-6-({[(2-methyl-2-propanyl)oxy]carbonyl}amino)benzoic acid structure](https://static.chemtradehub.com/structs/104/1048919-15-8-ba81.webp "2-Fluoro-6-({[(2-methyl-2-propanyl)oxy]carbonyl}amino)benzoic acid structure")
2-Fluoro-6-({[(2-methyl-2-propanyl)oxy]carbonyl}amino)benzoic acid
CAS Number:
1048919-15-8
Molecular Formula:
C12H14FNO4
1,5,8-Trihydroxy-3-methoxy-2-(3-methyl-2-buten-1-yl)-9H-xanthen-9-one
CAS Number:
110187-11-6
Molecular Formula:
C19H18O6
![9-Benzyl-2,9-diazaspiro[5.5]undecane dihydrochloride structure](https://static.chemtradehub.com/structs/119/1198286-24-6-4781.webp "9-Benzyl-2,9-diazaspiro[5.5]undecane dihydrochloride structure")
9-Benzyl-2,9-diazaspiro[5.5]undecane dihydrochloride
CAS Number:
1198286-24-6
Molecular Formula:
C16H26Cl2N2
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![P-({[(2R)-1-(6-Amino-9H-purin-9-yl)-2-propanyl]oxy}methyl)-N-[(2S)-1-isopropoxy-1-oxo-2-propanyl]phosphonamidic acid — Hubei Yangxin Pharmaceutical Technology Co., Ltd.](https://static.chemtradehub.com/suppliers/67cded3957537e5c8069af88/67cded3957537e5c8069af88-logo.webp){kind=logo}
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![P-({[(2R)-1-(6-Amino-9H-purin-9-yl)-2-propanyl]oxy}methyl)-N-[(2S)-1-isopropoxy-1-oxo-2-propanyl]phosphonamidic acid — ShenZhenZhenJiangShengWuJiShu Co Ltd](https://static.chemtradehub.com/suppliers/67cec9142b2de6e8e95a51e7/67cec9142b2de6e8e95a51e7-logo.webp){kind=logo}