P-({[(2R)-1-(6-Amino-9H-purin-9-yl)-2-propanyl]oxy}methyl)-N-[(2S)-1-isopropoxy-1-oxo-2-propanyl]phosphonamidic acid(CAS: 851456-00-3)

P-({[(2R)-1-(6-Amino-9H-purin-9-yl)-2-propanyl]oxy}methyl)-N-[(2S)-1-isopropoxy-1-oxo-2-propanyl]phosphonamidic acid is a crystalline compound with a molecular weight of approximately 642.37 g/mol. It is soluble in water and organic solvents. The compound exhibits moderate reactivity, particularly towards nucleophilic substitution reactions.

P-({[(2R)-1-(6-Amino-9H-purin-9-yl)-2-propanyl]oxy}methyl)-N-[(2S)-1-isopropoxy-1-oxo-2-propanyl]phosphonamidic acid is synthesized via a multi-step process involving the protection of the amino group, phosphonation, and subsequent deprotection. Commonly used catalysts include various organometallic reagents, and the overall yield is around 70-80%.

P-({[(2R)-1-(6-Amino-9H-purin-9-yl)-2-propanyl]oxy}methyl)-N-[(2S)-1-isopropoxy-1-oxo-2-propanyl]phosphonamidic acid is primarily used in pharmaceuticals for developing new drugs. It may also have potential applications in the synthesis of polymers and as a reagent in analytical chemistry for sensor development and semiconductors.

When handling P-({[(2R)-1-(6-Amino-9H-purin-9-yl)-2-propanyl]oxy}methyl)-N-[(2S)-1-isopropoxy-1-oxo-2-propanyl]phosphonamidic acid, proper personal protective equipment (PPE) should be used, including gloves, goggles, and a lab coat. Work should be conducted in a fume hood to avoid inhalation. In case of spill, neutralize the spill with an appropriate base and then clean up according to standard safety protocols. Always refer to the Safety Data Sheet (SDS) for detailed handling information.