2,5-Difluorobenzamide

Basic Information

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CAS Number

85118-03-2

Molecular Formula

C7H5F2NO

Molecular Weight

157.12 g/mol

Basic Physical Properties

Melting Point

114 °C

Boiling Point

194.2℃/760mmHg

SMILES

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Fc1ccc(c(c1)C(=O)N)F

InChI

InChI=1S/C7H5F2NO/c8-4-1-2-6(9)5(3-4)7(10)11/h1-3H,(H2,10,11)

InChIKey

BJKWHAILFUUIRT-UHFFFAOYSA-N

LogP

1.0637

Topological Polar Surface Area

43.09 Å²

Hydrogen Bond Donor/Acceptor

2 / 2

Complexity

163

Safety Information

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Hazard Statement

Hazard Class

Class IRRITANT Class IRRITANT

Synonyms & References

English

2-Amino-1-(2,5-difluorophenyl)ethanone
2,5-Difluorobenzamide
Benzamide, 2,5-difluoro-
BJKWHAILFUUIRT-UHFFFAOYSA-N
3,6-difluorobenzamide
2,5-Difluorobenzamide #
Benzamide,2,5-difluoro-
2,5-bis(fluoranyl)benzamide
2,5-Difluorobenzamide, AldrichCPR
KM2287
SBB087197
VZ22748
AM82952
AK162940
ST24038744
ST50824625
A841220

MDL Number

MFCD00015548

Customs Code

2924299090

FAQ

What regulatory guidelines apply to 2,5-Difluorobenzamide (CAS: 85118-03-2)?

2,5-Difluorobenzamide (CAS: 85118-03-2) falls under the GHS classification as a hazardous chemical due to its potential for skin and eye irritation. It is subject to REACH regulations in the European Union, requiring registration where the annual production or import quantity exceeds 1 ton. The FDA and EPA may also have specific handling and storage regulations for this compound, especially in pharmaceutical and agricultural applications.

Are there alternatives to 2,5-Difluorobenzamide (CAS: 85118-03-2) in synthesis?

For synthesis purposes, some alternatives to 2,5-Difluorobenzamide include 2,4-Difluorobenzamide and 3,5-Difluorobenzamide. These compounds may offer similar reactivity profiles, but their availability and cost should be considered. Other substitutes like 2-Fluorobenzamide and 4-Fluorobenzamide can also be explored based on the specific requirements of the reaction.

What is the market or research trend for 2,5-Difluorobenzamide (CAS: 85118-03-2)?

The market for 2,5-Difluorobenzamide (CAS: 85118-03-2) is growing due to its potential in drug discovery and synthesis. Research trends focus on its use as a precursor in the development of new pharmaceuticals and agrochemicals. Market dynamics show increasing interest in cost-effective production methods and sustainable alternatives to traditional synthesis routes.

How should waste containing 2,5-Difluorobenzamide (CAS: 85118-03-2) be handled?

Waste containing 2,5-Difluorobenzamide (CAS: 85118-03-2) should be collected in appropriate containers and disposed of through professional waste disposal services. Incineration is a common method, but it must be done in compliance with local regulations. Environmental protection measures include neutralizing the waste before disposal to minimize environmental impact, and proper labeling of waste containers for safe transport.