1-(2,4-Difluorophenyl)-1-propanone

Basic Information

View in Editor

CAS Number

85068-30-0

Molecular Formula

C9H8F2O

Molecular Weight

170.16 g/mol

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Carboxylic Acids

Basic Chemical Raw Materials Organic Chemicals Ketones

Fine Chemicals Dyes and Pigments Organic Dyes

Fine Chemicals Specialty Chemicals UV Stabilizers

Agricultural Chemicals Pesticides Herbicides

Electronic Chemicals Semiconductor Materials Etchants

Basic Physical Properties

Boiling Point

51-52 ºC (1.5 mmHg)

Density

1.193

Flash Point

76 ºC

Refractive Index

1.4835-1.4855

SMILES

View in Editor

CCC(=O)c1ccc(F)cc1F

InChI

InChI=1S/C9H8F2O/c1-2-9(12)7-4-3-6(10)5-8(7)11/h3-5H,2H2,1H3

InChIKey

UZWOADNMVRRYDE-UHFFFAOYSA-N

LogP

2.557500000000001

Topological Polar Surface Area

17.07 Å²

Hydrogen Bond Donor/Acceptor

0 / 1

Complexity

170

Safety Information

View Safety Information

Hazard Statement

H227 Combustible liquid
Flammable liquids

H315 Causes skin irritation
Skin corrosion/irritation

H319 Causes serious eye irritation
Serious eye damage/eye irritation

Hazard Class

Class IRRITANT Class IRRITANT

Synonyms & References

English

2',4'-Difluoropropiophenone
1-(2,4-Difluorophenyl)propan-1-one
2 ,4 -Difluoropropiophenone
1-(2,4-Difluorophenyl)-1-propanone
2,4-Difluoropropiophenone
1-Propanone, 1-(2,4-difluorophenyl)-
UZWOADNMVRRYDE-UHFFFAOYSA-N
2,4-Defluoropropiophenone
1-(2.4-difluoro-phenyl)-propan-1-one
KSC654A2R
2\\',4\\'-Difluoropropiophenone
SBB064045
TRA0060115
VZ21800

MDL Number

MFCD00015507

Customs Code

2914700090

FAQ

What are the physical and chemical properties of 1-(2,4-Difluorophenyl)-1-propanone (CAS: 85068-30-0)?

1-(2,4-Difluorophenyl)-1-propanone (CAS: 85068-30-0) is a colorless or pale yellow liquid with a molecular weight of approximately 169.12 g/mol. It has a low solubility in water but is soluble in organic solvents like ethanol and acetone. Chemically, it is a ketone and exhibits reactivity typical of such compounds, including electrophilic aromatic substitution and nucleophilic addition reactions.

How is 1-(2,4-Difluorophenyl)-1-propanone (CAS: 85068-30-0) typically synthesized?

1-(2,4-Difluorophenyl)-1-propanone (CAS: 85068-30-0) is commonly synthesized via the Friedel-Crafts acylation of 2,4-difluorophenol with acetic anhydride. This reaction requires a Lewis acid catalyst, such as aluminum chloride, to promote electrophilic aromatic substitution, followed by dehydration to form the ketone.

What industries use 1-(2,4-Difluorophenyl)-1-propanone (CAS: 85068-30-0)?

1-(2,4-Difluorophenyl)-1-propanone (CAS: 85068-30-0) is primarily used in the pharmaceutical and chemical industries. It serves as a precursor in the synthesis of pharmaceuticals and can also be utilized in the development of materials such as polymers and sensors due to its functional groups.

What precautions should be taken when handling 1-(2,4-Difluorophenyl)-1-propanone (CAS: 85068-30-0)?

When handling 1-(2,4-Difluorophenyl)-1-propanone (CAS: 85068-30-0), it is crucial to use appropriate personal protective equipment (PPE) such as gloves, goggles, and lab coats. Handle the compound in a well-ventilated area or with the use of a fume hood. Spills should be cleaned up using appropriate absorbent materials and disposed of according to local regulations. Always refer to the Safety Data Sheet (SDS) for detailed handling instructions.