1-(2,4-Difluorophenyl)-1-propanone(CAS: 85068-30-0)

1-(2,4-Difluorophenyl)-1-propanone (CAS: 85068-30-0) is a colorless or pale yellow liquid with a molecular weight of approximately 169.12 g/mol. It has a low solubility in water but is soluble in organic solvents like ethanol and acetone. Chemically, it is a ketone and exhibits reactivity typical of such compounds, including electrophilic aromatic substitution and nucleophilic addition reactions.

1-(2,4-Difluorophenyl)-1-propanone (CAS: 85068-30-0) is commonly synthesized via the Friedel-Crafts acylation of 2,4-difluorophenol with acetic anhydride. This reaction requires a Lewis acid catalyst, such as aluminum chloride, to promote electrophilic aromatic substitution, followed by dehydration to form the ketone.

1-(2,4-Difluorophenyl)-1-propanone (CAS: 85068-30-0) is primarily used in the pharmaceutical and chemical industries. It serves as a precursor in the synthesis of pharmaceuticals and can also be utilized in the development of materials such as polymers and sensors due to its functional groups.

When handling 1-(2,4-Difluorophenyl)-1-propanone (CAS: 85068-30-0), it is crucial to use appropriate personal protective equipment (PPE) such as gloves, goggles, and lab coats. Handle the compound in a well-ventilated area or with the use of a fume hood. Spills should be cleaned up using appropriate absorbent materials and disposed of according to local regulations. Always refer to the Safety Data Sheet (SDS) for detailed handling instructions.