Alogliptin Benzoate

Basic Information

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CAS Number

850649-62-6

Molecular Formula

C25H27N5O4

Molecular Weight

461.51 g/mol

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Carboxylic Acids

Basic Chemical Raw Materials Organic Chemicals Amines

Basic Chemical Raw Materials Organic Chemicals Nitriles

Basic Chemical Raw Materials Organic Chemicals Heterocyclic Compounds

Pharmaceutical Chemicals Pharmaceutical Intermediates Heterocyclic Intermediates

Fine Chemicals Dyes and Pigments Organic Dyes

Fine Chemicals Surfactants Anionic Surfactants

Laboratory Chemicals Research Chemicals Biochemical Reagents

Basic Physical Properties

Physical State

Powder

Boiling Point

671.2°C at 760 mmHg

Flash Point

359.7°C

SMILES

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Cn1c(=O)cc(n(c1=O)Cc2ccccc2C#N)N3CCC[C@H](C3)N.c1ccc(cc1)C(=O)O

InChI

InChI=1S/C18H21N5O2.C7H6O2/c1-21-17(24)9-16(22-8-4-7-15(20)12-22)23(18(21)25)11-14-6-3-2-5-13(14)10-19;8-7(9)6-4-2-1-3-5-6/h2-3,5-6,9,15H,4,7-8,11-12,20H2,1H3;1-5H,(H,8,9)/t15-;/m1./s1

InChIKey

KEJICOXJTRHYAK-XFULWGLBSA-N

LogP

2.54458

Complexity

726

Safety Information

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Hazard Statement

H302 Harmful if swallowed
Acute toxicity, oral

H315 Causes skin irritation
Skin corrosion/irritation

H319 Causes serious eye irritation
Serious eye damage/eye irritation

H335 May cause respiratory irritation
Specific target organ toxicity, single exposure; Respiratory tract irritation

Synonyms & References

English

Alogliptin benzoate
2-[[6-[(3R)-3-Amino-1-piperidinyl]-3,4-dihydro-3-methyl-2,4-dioxo-1(2H)-pyrimidinyl]methyl]benzonitrile benzoate
2-[[6-[(3R)-3-aMino-1-piperidinyl]-3,4-dihydro-3-Methyl-2,4-dioxo-1(2H)-pyriMidinyl]Methyl]-Benzonitrile Monobenzoate
SYR 322
Nesina
2-[[6-[(3R)-3-aminopiperidin-1-yl]-3-methyl-2,4-dioxopyrimidin-1-yl]methyl]benzonitrile,benzoic acid
2-[6-[3(R)-Aminopiperidin-1-yl]-3-methyl-2,4-dioxo-1,2,3,4-tetrahydropyrimidin-1-ylmethyl]benzonitrile benzoate
alogliptin
Alogliptin (Benzoate)
alogliptin monobenzoate
SYR32
Vipidia (TN)
Alogliptin Benzoate
(R)-2-((6-(3-aminopiperidin-1-yl)-3-methyl-2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl)methyl)benzonitrile
benzoic acid (1:1)

MDL Number

MFCD09833195

FAQ

What is [compound name] (CAS: 850649-62-6)?

Alogliptin Benzoate is a pharmaceutical compound used as a prodrug of alogliptin, which is an inhibitor of dipeptidyl peptidase-4 (DPP-4). It has the chemical formula C24H29N5O6S and is a white to off-white crystalline powder with good solubility in certain solvents. It is commonly used in the treatment of type 2 diabetes.

What are the main uses of [compound name] (CAS: 850649-62-6)?

The primary use of Alogliptin Benzoate is in pharmaceutical applications, specifically as a prodrug for the antidiabetic medication alogliptin. It is used in oral formulations to improve bioavailability and reduce gastrointestinal side effects. It may also be used in research and development for drug delivery systems.

Is [compound name] (CAS: 850649-62-6) safe?

Alogliptin Benzoate is generally considered safe when used as directed in medical treatments. However, like all medications, it may have side effects and should be handled with care. It is important to follow safety guidelines and consult healthcare professionals for proper use. Safety standards are in place to ensure its appropriate handling in pharmaceutical settings.

How should [compound name] (CAS: 850649-62-6) be stored?

Alogliptin Benzoate should be stored in a cool, dry place away from moisture and light. It is typically kept at a temperature between 15°C to 30°C. Proper storage helps maintain its stability and efficacy. Always check the specific storage instructions on the product packaging for best results.