5'-Guanylic acid

Basic Information

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CAS Number

85-32-5

Molecular Formula

C10H14N5O8P

Molecular Weight

363.22 g/mol

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Carboxylic Acids

Basic Chemical Raw Materials Organic Chemicals Ethers

Basic Chemical Raw Materials Organic Chemicals Amines

Basic Chemical Raw Materials Organic Chemicals Heterocyclic Compounds

Pharmaceutical Chemicals Pharmaceutical Intermediates Heterocyclic Intermediates

Fine Chemicals Dyes and Pigments Organic Dyes

Agricultural Chemicals Pesticides Insecticides

Basic Physical Properties

Solubility

Water

SMILES

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O=P(O)(OC[C@@H]1[C@H]([C@H]([C@H](N2C=NC3=C2N=C(N)NC3=O)O1)O)O)O

InChI

InChI=1S/C10H14N5O8P/c11-10-13-7-4(8(18)14-10)12-2-15(7)9-6(17)5(16)3(23-9)1-22-24(19,20)21/h2-3,5-6,9,16-17H,1H2,(H2,19,20,21)(H3,11,13,14,18)/t3-,5-,6-,9-/m1/s1

InChIKey

RQFCJASXJCIDSX-UUOKFMHZSA-N

LogP

-2.5696999999999988

Topological Polar Surface Area

206.03999999999994 Å²

Hydrogen Bond Donor/Acceptor

7 / 13

Complexity

598

Safety Information

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Storage Conditions

2-8℃

Synonyms & References

English

5'-Guanylic acid
Guanosine 5'-phosphate
[(2R,3S,4R,5R)-5-(2-Amino-6-oxo-3H-purin-9-yl)-3,4-dihydroxyoxolan-2-yl]methyl dihydrogen phosphate
Guanosine 5'-Monophosphate Hydrate
5-GUANOSINE MONOPHOSPHATE
5'-inosine monophosphate
GUANIDINE PHOSPHATE, MONOBASIC
Guanidylic acid
GUANILICACID
GUANILLICACID
guanosine
GUANOSINE 5'-MONOPHOSPHATE
GUANOSINE 5'-MONOPHOSPHORIC ACID
GUANOSINE MONOPHOSPHATE
GUANOSINE-5'-MONOPHOSPHATE
GUANOSINE-5'-MONOPHOSPHATE FREE ACID
GUANOSINE-5'-MONOPHOSPHATE NA
GUANOSINE-5'-MONOPHOSPHONATE
GUANOSINE-5'-MONOPHOSPHORIC ACID
guanylate
Guanylic acid
Guanylic Aicd
Guo-5'-P
Guanidine monophosphate,Guanosine 5'-(dihydrogen phosphate),Guanosine 5'-monophosphate,Guanosine5'-p...

MDL Number

MFCD00057066

FAQ

What are the physical and chemical properties of 5'-Guanylic acid (CAS: 85-32-5)?

5'-Guanylic acid (CAS: 85-32-5) is a white crystalline solid with a molecular weight of approximately 298.2 g/mol. It is slightly soluble in water and ethanol. Chemically, it is relatively stable but can react with strong acids to form guanine. It is a key intermediate in the synthesis of nucleotides and nucleic acids.

How is 5'-Guanylic acid (CAS: 85-32-5) typically synthesized?

5'-Guanylic acid (CAS: 85-32-5) is synthesized through the condensation of guanine with 5'-phosphoric acid. Commonly, this is achieved using acetic anhydride as a condensing agent. The reaction is typically carried out under anhydrous conditions to ensure high yield and purity.

What industries use 5'-Guanylic acid (CAS: 85-32-5)?

5'-Guanylic acid (CAS: 85-32-5) is primarily used in the pharmaceutical industry for the production of nucleoside analogs and nucleotide drugs. It also finds applications in biochemical research and the development of sensors and semiconductors due to its nucleotide structure.

What precautions should be taken when handling 5'-Guanylic acid (CAS: 85-32-5)?

When handling 5'-Guanylic acid (CAS: 85-32-5), it is essential to wear appropriate personal protective equipment (PPE), including gloves, safety goggles, and a lab coat. Store it in a cool, dry place away from direct sunlight and ensure proper ventilation in the laboratory. In case of spill, neutralize with a base and dispose of according to local regulations. Always refer to the Safety Data Sheet (SDS) for detailed handling instructions.