6-Thioguanosine

Basic Information

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CAS Number

85-31-4

Molecular Formula

C10H13N5O4S

Molecular Weight

299.31 g/mol

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Ethers

Basic Chemical Raw Materials Organic Chemicals Amines

Basic Chemical Raw Materials Organic Chemicals Heterocyclic Compounds

Pharmaceutical Chemicals Pharmaceutical Intermediates Heterocyclic Intermediates

Fine Chemicals Dyes and Pigments Organic Dyes

Basic Physical Properties

Melting Point

224-227 ºC

Boiling Point

756.9°C at 760 mmHg

Density

2.18

Refractive Index

1.6460 (estimate)

SMILES

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OC[C@@H]1[C@H]([C@H]([C@H](N2C=NC3=C2NC(N)=NC3=S)O1)O)O

InChI

InChI=1S/C10H13N5O4S/c11-10-13-7-4(8(20)14-10)12-2-15(7)9-6(18)5(17)3(1-16)19-9/h2-3,5-6,9,16-18H,1H2,(H3,11,13,14,20)/t3-,5-,6-,9-/m1/s1

InChIKey

OTDJAMXESTUWLO-UUOKFMHZSA-N

LogP

-1.31741

Topological Polar Surface Area

142.44 Å²

Hydrogen Bond Donor/Acceptor

6 / 9

Complexity

367

Synonyms & References

English

6-Thioguanosine
2-Amino-6-mercaptopurine-9-D-riboside Hydrate
2-AMINO-6-MERCAPTOPURINE RIBOSIDE
2-Amino-6-mercaptopurine-9-D-riboside
6-Mercaptoguanine riboside
6-MERCAPTOGUANOSINE
Guanosine, 6-thio-
2-amino-6-mercaptopurine ribose
6-thioguanineribose
6-thio-guanosin
6-thio-guanosine
ribosylthioguanine
sri759
TGR
thioguanineriboside
thioguanosine
2-Amino-6-mercaptopurine ribonucleoside
2-Amino-9-(beta-D-ribofuranosyl)purine-6-thiol

MDL Number

MFCD23102202

Customs Code

2934999090

FAQ

What regulatory guidelines apply to 6-Thioguanosine (CAS: 85-31-4)?

6-Thioguanosine (CAS: 85-31-4) is regulated under the Globally Harmonized System of Classification and Labeling of Chemicals (GHS), which includes specific hazard classifications. It is also subject to the REACH regulations in the European Union, which require registration, evaluation, and authorization of chemical substances. Additionally, the U.S. Food and Drug Administration (FDA) and Environmental Protection Agency (EPA) may have specific regulations regarding its use and handling in pharmaceutical and industrial applications.

Are there alternatives to 6-Thioguanosine (CAS: 85-31-4) in synthesis?

There are several alternatives to 6-Thioguanosine (CAS: 85-31-4) that can be used in synthesis, such as thymidine and deoxyguanosine. These alternatives may offer similar properties or can be used as precursors in the synthesis of 6-Thioguanosine. Other substitutes include analogous compounds with similar functional groups, which can serve as effective alternatives depending on the specific requirements of the synthesis.

What is the market or research trend for 6-Thioguanosine (CAS: 85-31-4)?

The market for 6-Thioguanosine (CAS: 85-31-4) is primarily driven by pharmaceutical and research applications, particularly in the study of nucleic acid chemistry and enzymology. Recent research trends focus on the use of 6-Thioguanosine as a mutagenic agent and in the development of RNA interference technologies. Market trends suggest increasing demand in academic and industrial settings as new applications are discovered.

How should waste containing 6-Thioguanosine (CAS: 85-31-4) be handled?

Waste containing 6-Thioguanosine (CAS: 85-31-4) should be collected in appropriate containers and stored in a well-ventilated area away from fire and heat sources. Disposal should follow local, state, and federal regulations, as it may be considered a hazardous material due to its chemical properties. Professional waste disposal services are recommended for safe incineration or other environmentally friendly disposal methods. Environmental protection precautions, such as proper containment and minimal exposure, are crucial during handling and disposal.