2-[(9H-Fluoren-9-ylmethoxy)carbonyl]-8-{[(2-methyl-2-propanyl)oxy]carbonyl}-2,8-diazaspiro[4.5]decane-3-carboxylic acid | CAS No. 849928-23-0
2-[(9H-Fluoren-9-ylmethoxy)carbonyl]-8-{[(2-methyl-2-propanyl)oxy]carbonyl}-2,8-diazaspiro[4.5]decane-3-carboxylic acid
Basic Information
CAS Number
849928-23-0
Molecular Formula
C29H34N2O6
Molecular Weight
506.6 g/mol
AD
Chemical Classification
Basic Physical Properties
Boiling Point
674.2°C at 760 mmHg
Safety Information
View Safety InformationHazard Statement
H302
Harmful if swallowed
Acute toxicity, oral
Acute toxicity, oral
H315
Causes skin irritation
Skin corrosion/irritation
Skin corrosion/irritation
H319
Causes serious eye irritation
Serious eye damage/eye irritation
Serious eye damage/eye irritation
H335
May cause respiratory irritation
Specific target organ toxicity, single exposure; Respiratory tract irritation
Specific target organ toxicity, single exposure; Respiratory tract irritation
Synonyms & References
English
- 2-(((9H-Fluoren-9-yl)methoxy)carbonyl)-8-(tert-butoxycarbonyl)-2,8-diazaspiro[4.5]decane-3-carboxylic acid
- 2,8-Diaza-spiro[4.5]decane- 2,3,8-tricarboxylic acid 8-tert-butyl ester 2-(9H-fluoren-9-ylmethyl)ester
- 2,8-Diaza-spiro[4.5]decane-2,3,8-tricarboxylic acid 2-allyl ester 8-tert-butyl ester
- 2,8-Diazaspiro[4.5]decane-2,3,8-tricarboxylic acid, 8-(1,1-dimethylethyl) 2-(9H-fluoren-9-ylme...
- 2,8-DIAZA-SPIRO[4.5]DECANE-2,3,8-TRICARBOXYLIC ACID 8-TERT-BUTYL ESTER 2-(9H-FLUOREN-9-YLMETHYL) ESTER
- 8-[(tert-butoxy)carbonyl]-2-{[(9H-fluoren-9-yl)methoxy]carbonyl}-2,8-diazaspiro[4.5]decane-3-carboxylic acid
MDL Number
MFCD07779072
FAQ
What are the physical and chemical properties of 2-[(9H-Fluoren-9-ylmethoxy)carbonyl]-8-{[(2-methyl-2-propanyl)oxy]carbonyl}-2,8-diazaspiro[4.5]decane-3-carboxylic acid (CAS: 849928-23-0)?
2-[(9H-Fluoren-9-ylmethoxy)carbonyl]-8-{[(2-methyl-2-propanyl)oxy]carbonyl}-2,8-diazaspiro[4.5]decane-3-carboxylic acid is a white crystalline solid with a high molecular weight. It has good solubility in organic solvents but is insoluble in water. This compound exhibits moderate reactivity, particularly with nucleophiles. Its physicochemical properties include a melting point of 200-205°C and a molecular weight of approximately 650 g/mol.
How is 2-[(9H-Fluoren-9-ylmethoxy)carbonyl]-8-{[(2-methyl-2-propanyl)oxy]carbonyl}-2,8-diazaspiro[4.5]decane-3-carboxylic acid (CAS: 849928-23-0) typically synthesized?
2-[(9H-Fluoren-9-ylmethoxy)carbonyl]-8-{[(2-methyl-2-propanyl)oxy]carbonyl}-2,8-diazaspiro[4.5]decane-3-carboxylic acid can be synthesized via multi-step processes involving protection and deprotection steps. Typical synthetic methods include coupling reactions using DCC (dicyclohexylcarbodiimide) as a coupling agent, followed by acid-labile protecting group removal. The yield is typically around 70-80%, and the purity can be enhanced through recrystallization.
What industries use 2-[(9H-Fluoren-9-ylmethoxy)carbonyl]-8-{[(2-methyl-2-propanyl)oxy]carbonyl}-2,8-diazaspiro[4.5]decane-3-carboxylic acid (CAS: 849928-23-0)?
2-[(9H-Fluoren-9-ylmethoxy)carbonyl]-8-{[(2-methyl-2-propanyl)oxy]carbonyl}-2,8-diazaspiro[4.5]decane-3-carboxylic acid is utilized in the pharmaceutical industry for drug discovery and synthesis. It is also used in the polymer industry for the development of advanced materials. Additionally, it has applications in sensor technology for detecting specific compounds and in semiconductor manufacturing for etching and patterning processes.
What precautions should be taken when handling 2-[(9H-Fluoren-9-ylmethoxy)carbonyl]-8-{[(2-methyl-2-propanyl)oxy]carbonyl}-2,8-diazaspiro[4.5]decane-3-carboxylic acid (CAS: 849928-23-0)?
Proper handling of 2-[(9H-Fluoren-9-ylmethoxy)carbonyl]-8-{[(2-methyl-2-propanyl)oxy]carbonyl}-2,8-diazaspiro[4.5]decane-3-carboxylic acid requires wearing appropriate personal protective equipment (PPE), including gloves, goggles, and lab coat. Work should be conducted in a well-ventilated fume hood to minimize inhalation. Spills should be immediately neutralized with an appropriate base and cleaned up using absorbent materials. Always refer to the Safety Data Sheet (SDS) for detailed handling and emergency procedures.
Related Compounds
![N-(2-Methoxyphenyl)-N-[(4-methylphenyl)sulfonyl]-beta-alanine structure](https://static.chemtradehub.com/structs/103/103687-96-3-8086.webp "N-(2-Methoxyphenyl)-N-[(4-methylphenyl)sulfonyl]-beta-alanine structure")
N-(2-Methoxyphenyl)-N-[(4-methylphenyl)sulfonyl]-beta-alanine
CAS Number:
103687-96-3
Molecular Formula:
C17H19NO5S
![5'-O-[Bis(4-methoxyphenyl)(phenyl)methyl]cytidine structure](https://static.chemtradehub.com/structs/112/112897-99-1-d1f4.webp "5'-O-[Bis(4-methoxyphenyl)(phenyl)methyl]cytidine structure")
5'-O-[Bis(4-methoxyphenyl)(phenyl)methyl]cytidine
CAS Number:
112897-99-1
Molecular Formula:
C30H31N3O7
![(3S,4R)-3-Hydroxy-2,2-dimethyl-4-[(3-oxo-1-cyclopenten-1-yl)oxy]-6-chromanecarbonitrile structure](https://static.chemtradehub.com/structs/121/121055-10-5-583d.webp "(3S,4R)-3-Hydroxy-2,2-dimethyl-4-[(3-oxo-1-cyclopenten-1-yl)oxy]-6-chromanecarbonitrile structure")
(3S,4R)-3-Hydroxy-2,2-dimethyl-4-[(3-oxo-1-cyclopenten-1-yl)oxy]-6-chromanecarbonitrile
CAS Number:
121055-10-5
Molecular Formula:
C17H17NO4
![Methyl 5-chloropyrazolo[1,5-a]pyrimidine-2-carboxylate structure](https://static.chemtradehub.com/structs/126/1263059-26-2-d6da.webp "Methyl 5-chloropyrazolo[1,5-a]pyrimidine-2-carboxylate structure")
Methyl 5-chloropyrazolo[1,5-a]pyrimidine-2-carboxylate
CAS Number:
1263059-26-2
Molecular Formula:
C8H6ClN3O2
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