1-(5-Chloro-2-hydroxy-3-nitrophenyl)ethanone

Basic Information

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CAS Number

84942-40-5

Molecular Formula

C8H6ClNO4

Molecular Weight

215.59 g/mol

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Carboxylic Acids

Basic Chemical Raw Materials Organic Chemicals Ketones

Fine Chemicals Dyes and Pigments Organic Dyes

Agricultural Chemicals Pesticides Herbicides

Basic Physical Properties

Melting Point

131.0 to 135.0 deg-C

Boiling Point

260.7 °C at 760 mmHg

Density

1.505

Flash Point

260.7 °C at 760 mmHg

Refractive Index

1.609

SMILES

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Clc1cc([N+](=O)[O-])c(c(c1)C(=O)C)O

InChI

InChI=1S/C8H6ClNO4/c1-4(11)6-2-5(9)3-7(8(6)12)10(13)14/h2-3,12H,1H3

InChIKey

IUNBIQBAYUBIFD-UHFFFAOYSA-N

LogP

2.67960

Complexity

252

Safety Information

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Hazard Statement

H315 Causes skin irritation
Skin corrosion/irritation

H319 Causes serious eye irritation
Serious eye damage/eye irritation

Synonyms & References

English

1-(5-Chloro-2-hydroxy-3-nitrophenyl)ethanone
5-Chloro-2-Hydroxy-3-Nitro Acetophenone
5'-Chloro-2'-hydroxy-3'-nitroacetophenone
5'-Chloro-2′-hydroxy-3′-nitroacetophenone
1-(5-CHLORO-2-HYDROXY-3-NITRO-PHENYL)ETHANONE
1-acetyl-5-chloro-2-hydroxy-3-nitrobenzene
2-ACETYL-6-NITRO-4-CHLOROPHENOL
2'-HYDROXY-3'-NITRO-5'-CHLORO ACETOPHENONE
2-HYDROXY-3-NITROACETOPHENONE
5-CHLORO -3-NITRO-2-HYDROXY ACETOPHENONE
5'-CHLORO-2'-HYDROXY-3'-NITROACETOPHE
2-Acetyl-6-nitro-4-chloro phenol
2-acetyl-4-chloro-6-nitrophenol
Ethanone, 1-(5-chloro-2-hydroxy-3-nitrophenyl)-
Benzoic acid,5-chloro-2-hydroxy-3-nitro-
PubChem3355
5-chloro-2-hydroxy-3-nitroacetophenone
5-chloro-3-nitro-2-hydroxyacetophenone
M

MDL Number

MFCD00191921

Customs Code

2914700090

FAQ

What are the physical and chemical properties of 1-(5-Chloro-2-hydroxy-3-nitrophenyl)ethanone (CAS: 84942-40-5)?

1-(5-Chloro-2-hydroxy-3-nitrophenyl)ethanone (CAS: 84942-40-5) has a crystalline form and a molecular weight of approximately 291.04 g/mol. It is poorly soluble in water but soluble in organic solvents. This compound is known for its high reactivity due to the presence of nitro and hydroxy groups. It can undergo various reactions such as reduction, nitration, and esterification.

How is 1-(5-Chloro-2-hydroxy-3-nitrophenyl)ethanone (CAS: 84942-40-5) typically synthesized?

1-(5-Chloro-2-hydroxy-3-nitrophenyl)ethanone (CAS: 84942-40-5) is typically synthesized through the nitration of 1-(5-chloro-2-hydroxyphenyl)ethanone followed by the introduction of the nitro group. This involves using nitric acid and sulfuric acid as the reagents. The reaction is carried out under controlled conditions to achieve high yield and selectivity.

What industries use 1-(5-Chloro-2-hydroxy-3-nitrophenyl)ethanone (CAS: 84942-40-5)?

1-(5-Chloro-2-hydroxy-3-nitrophenyl)ethanone (CAS: 84942-40-5) is used in the pharmaceutical industry for the synthesis of certain drugs. It is also utilized in the polymer industry for the development of novel materials. Additionally, it finds applications in the production of sensors and as a chemical intermediate in semiconductor manufacturing processes.

What precautions should be taken when handling 1-(5-Chloro-2-hydroxy-3-nitrophenyl)ethanone (CAS: 84942-40-5)?

When handling 1-(5-Chloro-2-hydroxy-3-nitrophenyl)ethanone (CAS: 84942-40-5), it is crucial to wear appropriate personal protective equipment (PPE) such as gloves, safety goggles, and a lab coat. Handle the compound in a well-ventilated area or a fume hood. Ensure proper storage in a cool, dry place, away from incompatible materials. In case of a spill, use appropriate spill clean-up procedures and consult the Safety Data Sheet (SDS) for detailed instructions.