1-Methyl-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-pyrazole

Basic Information

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CAS Number

847818-74-0

Molecular Formula

C10H17BN2O2

Molecular Weight

208.07 g/mol

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Heterocyclic Compounds

Pharmaceutical Chemicals Pharmaceutical Intermediates Heterocyclic Intermediates

Basic Physical Properties

Melting Point

69.0 to 73.0 deg-C

Boiling Point

355°C at 760 mmHg

Water Solubility

Slightly soluble in water.

Flash Point

168.5℃

SMILES

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Cn1nccc1B2OC(C)(C)C(C)(C)O2

InChI

InChI=1S/C10H17BN2O2/c1-9(2)10(3,4)15-11(14-9)8-6-7-12-13(8)5/h6-7H,1-5H3

InChIKey

HLXOVAMYQUFLPE-UHFFFAOYSA-N

LogP

0.7192999999999998

Topological Polar Surface Area

36.28 Å²

Hydrogen Bond Donor/Acceptor

0 / 4

Complexity

242

Safety Information

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GHS Hazard Pictograms

H302

H315

H319

H335

Hazard Statement

H302 Harmful if swallowed
Acute toxicity, oral

H315 Causes skin irritation
Skin corrosion/irritation

H319 Causes serious eye irritation
Serious eye damage/eye irritation

H335 May cause respiratory irritation
Specific target organ toxicity, single exposure; Respiratory tract irritation

Hazard Class

Class IRRITANT Class IRRITANT

Synonyms & References

English

1-Methyl-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-pyrazole
1-Methyl-1H-pyrazole-5-boronic acid pinacol ester
1-Methyl-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)pyrazole
1-METHYL-5-(4,4,5,5-TETRAMETHYL-[1,3,2]DIOXABOROLAN-2-YL)-1H-PYRAZOLE
2-(1-Methyl-1H-pyrazol-5-yl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane
2-Methyl-3-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-2H-pyrazole
1-Methylpyrazole-5-boronic Acid Pinacol Ester
4,4,5,5-Tetramethyl-2-(1-methylpyrazol-5-yl)-1,3,2-dioxaborolane
1-Methyl-3-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-pyrazole
1-methyl-5-(tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-pyrazole
1H-PYRAZOLE, 1-METHYL-5-(4,4,5,5-TETRAMETHYL-1,3,2-DIOXABOROLAN-2-YL)-
4,4,5,5-tetramethyl-2-(1-methylpyrazol-5-yl

MDL Number

MFCD05861380

Customs Code

2934999090

FAQ

What is 1-Methyl-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-pyrazole (CAS: 847818-74-0)?

1-Methyl-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-pyrazole (CAS: 847818-74-0) is a synthetic organic compound containing a pyrazole ring substituted with a boronic acid group. It is commonly used as a building block in organic synthesis, particularly in pharmaceutical research. The compound exhibits stability under normal conditions and is characterized by its polar nature and potential reactivity in catalytic processes.

What are the main uses of 1-Methyl-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-pyrazole (CAS: 847818-74-0)?

This compound is primarily used in pharmaceutical development for its utility in synthesizing drug molecules. It serves as a key intermediate in the preparation of various biologically active compounds. Additionally, it finds applications in organic chemistry research, particularly in coupling reactions and functional group transformations. Its use is also relevant in industrial chemical processes involving boron-based reagents.

Is 1-Methyl-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-pyrazole (CAS: 847818-74-0) safe?

The safety of 1-Methyl-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-pyrazole (CAS: 847818-74-0) depends on its handling and exposure conditions. It is generally considered safe when used in controlled laboratory environments. However, standard safety precautions should be followed, such as wearing protective gloves and goggles. It is advisable to consult safety data sheets for detailed handling guidelines and exposure limits.

How should 1-Methyl-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-pyrazole (CAS: 847818-74-0) be stored?

1-Methyl-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-pyrazole (CAS: 847818-74-0) should be stored in a cool, dry place away from light. It is recommended to keep it in airtight containers to prevent moisture absorption. Storage at temperatures below 25°C is preferred to maintain stability and prevent degradation. Always ensure proper labeling and secure storage to avoid accidental exposure.