Fmoc-D-Val-OH | CAS No. 84624-17-9

Fmoc-D-Val-OH

Basic Information

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CAS Number

84624-17-9

Molecular Formula

C20H21NO4

Molecular Weight

339.39 g/mol

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Carboxylic Acids

Basic Chemical Raw Materials Organic Chemicals Ethers

Fine Chemicals Dyes and Pigments Organic Dyes

Fine Chemicals Surfactants Anionic Surfactants

Basic Physical Properties

Melting Point

144.0 to 148.0 deg-C

Water Solubility

Solubility in methanol (almost transparency). Slightly soluble in water.

Specific Rotation

17 º (c=1, DMF)

SMILES

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CC(C)C(C(=O)O)NC(=O)OCC1C2=CC=CC=C2C3=CC=CC=C13

InChI

InChI=1S/C20H21NO4/c1-12(2)18(19(22)23)21-20(24)25-11-17-15-9-5-3-7-13(15)14-8-4-6-10-16(14)17/h3-10,12,17-18H,11H2,1-2H3,(H,21,24)(H,22,23)/t18-/m1/s1

InChIKey

UGNIYGNGCNXHTR-GOSISDBHSA-N

LogP

3.6343000000000023

Topological Polar Surface Area

75.63000000000001 Å²

Hydrogen Bond Donor/Acceptor

2 / 5

Complexity

470

Safety Information

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Hazard Statement

H315 Causes skin irritation
Skin corrosion/irritation

H319 Causes serious eye irritation
Serious eye damage/eye irritation

H335 May cause respiratory irritation
Specific target organ toxicity, single exposure; Respiratory tract irritation

Synonyms & References

English

N-Fmoc-D-Valine
N-(9-fluorenylmethoxycarbonyl)-D-valine
Fmoc-D-Val-OH
NALPHA-9-Fluorenylmethoxycarbonyl-D-valine
N-[(9H-Fluoren-9-ylmethoxy)carbonyl]-D-valine
(2R)-2-(9H-fluoren-9-ylmethoxycarbonylamino)-3-methylbutanoic acid
(R)-2-((((9H-Fluoren-9-yl)methoxy)carbonyl) amino)-3-methylbutanoic acid
9-FLUORENYLMETHOXYCARBONYL-D-VALINE
FMOC-D-Valine
D-Fmoc-Val-Cl
FMOC-D-VAL
Fmoc-Val-OH
2-{[(9H-Fluoren-9-ylmethoxy)carbonyl]amino}-3-methylbutanoic acid
(R)-2-((((9H-Fluoren-9-yl)methoxy)carbonyl)amino)-3-methylbutanoic acid
D-Valine, N-[(9H-fluoren-9-ylmethoxy)carbonyl]-
PubChem10061
(((9H-fluoren-9-yl)methoxy)carbonyl)-D-valine
KSC447S9T
UGNIYGNGCNXHTR-GOSISDBHSA-N
ANW-3
N-Fmoc-D-valine
N-(9-Fluorenylmethoxycarbonyl)-D-valine
MFCD00062953
N-FMOC-D-VALINE
N-[(9H-Fluoren-9-ylmethoxy)carbonyl]-D-valine; (R)-N-Fmoc-valine; 289: PN: US20070042401 PAGE: 37 Claimed Protein; 980: PN: WO2006135786 PAGE: 70 Claimed Protein; D-Fmoc-Valine; N-(9-Fluorenylmethoxycarbonyl)-D-valine
(r)-n-fmoc-valine
CS-W009835
O10159
J-300297
(R)-2-(((9H-fluoren-9-yl)methoxy)carbonylamino)-3-methylbutanoic acid
N-ALPHA-(9-FLUORENYLMETHYLOXYCARBONYL)-D-VALINE

MDL Number

MFCD00062953

Customs Code

2924299090

FAQ

What is Fmoc-D-Val-OH (CAS: 84624-17-9)?

Fmoc-D-Val-OH (CAS: 84624-17-9) is a protected amino acid derivative, specifically the N-(9-fluorenylmethoxycarbonyl) form of D-valine. It has the chemical formula C19H27NO5 and appears as a white solid. This compound is widely used in peptide synthesis due to its stability and compatibility with solid-phase peptide synthesis (SPPS) techniques.

What are the main uses of Fmoc-D-Val-OH (CAS: 84624-17-9)?

Fmoc-D-Val-OH (CAS: 84624-17-9) is primarily used in pharmaceutical research for synthesizing peptides containing D-amino acids, which are critical in drug development. It also finds applications in biochemistry studies, protein engineering, and as a building block in functionalized organic compounds. Its utility stems from the Fmoc protecting group’s ease of removal under controlled conditions.

Is Fmoc-D-Val-OH (CAS: 84624-17-9) safe?

Fmoc-D-Val-OH (CAS: 84624-17-9) is generally considered safe when handled with proper laboratory precautions. It is non-toxic and does not pose significant hazards under normal conditions. However, protective measures such as gloves, goggles, and a well-ventilated workspace are recommended to avoid accidental exposure. Always follow safety guidelines for chemical handling in research settings.

How should Fmoc-D-Val-OH (CAS: 84624-17-9) be stored?

Fmoc-D-Val-OH (CAS: 84624-17-9) should be stored in a sealed, airtight container at room temperature (15-25°C) to maintain stability. It is sensitive to moisture and light, so storage in a dry, cool environment away from direct sunlight is essential. Keep the compound in a controlled atmosphere to preserve its purity and prevent degradation.