Aflibercept | CAS No. 845771-78-0

Aflibercept

Basic Information

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CAS Number

845771-78-0

Molecular Weight

0 g/mol

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Heterocyclic Compounds

Pharmaceutical Chemicals Pharmaceutical Intermediates Heterocyclic Intermediates

Agricultural Chemicals Pesticides Herbicides

Basic Physical Properties

SMILES

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BrC1=C(C([H])([H])[H])C2=C(SC(=C2C([H])([H])[H])Br)S1

InChI

InChI=1S/C8H6Br2S2/c1-3-5-4(2)7(10)12-8(5)11-6(3)9/h1-2H3

InChIKey

CAKZHCORWHLXLQ-UHFFFAOYSA-N

LogP

5.104640000000002

Topological Polar Surface Area

0.0 Å²

Hydrogen Bond Donor/Acceptor

0 / 0

Synonyms & References

English

Aflibercept

FAQ

What is Aflibercept (CAS: 845771-78-0)?

Aflibercept (CAS: 845771-78-0) is a recombinant fusion protein that binds vascular endothelial growth factor (VEGF) and placental growth factor (PlGF), used in the treatment of age-related macular degeneration, diabetic macular edema, and neovascular glaucoma.

What are the main uses of Aflibercept (CAS: 845771-78-0)?

Aflibercept (CAS: 845771-78-0) is primarily used in ophthalmology to treat conditions such as age-related macular degeneration, diabetic macular edema, and neovascular glaucoma. It is administered through intravitreal injection.

Is Aflibercept (CAS: 845771-78-0) safe?

Aflibercept (CAS: 845771-78-0) is generally considered safe when used under medical supervision. However, it may cause side effects such as cataracts, increased eye pressure, and retinal detachment. Proper patient monitoring and follow-up are essential to ensure safety.

How should Aflibercept (CAS: 845771-78-0) be stored?

Aflibercept (CAS: 845771-78-0) should be stored refrigerated at 2°C to 8°C (36°F to 46°F) in its original packaging. It should be protected from light and should not be frozen. The container should be kept tightly closed to maintain its stability and efficacy.