4-(5,5-Dimethyl-1,3,2-dioxaborinan-2-yl)isoquinoline | CAS No. 844891-01-6
4-(5,5-Dimethyl-1,3,2-dioxaborinan-2-yl)isoquinoline
Basic Information
CAS Number
844891-01-6
Molecular Formula
C14H16BNO2
Molecular Weight
241.1 g/mol
AD
Basic Physical Properties
Melting Point
123 °C
Synonyms & References
English
- Isoquinoline-4-boronic acid, neopentyl glycol ester
- AKOS004119286
- Isoquinoline-4-boronic acid, 2,2-dimethylpropane-1,3-diol cyclic ester
- AT15530
- J-521588
- AB25915
- AS-69215
- C14H16BNO2
- ISOQUINOLINE-4-BORONIC ACID 2,2-DIMETHYLPROPANEDIOL-1,3 CYCLIC ESTER
- 4-(5,5-dimethyl-1,3,2-dioxaborinan-2-yl)isoquinoline
- 844891-01-6
- CS-0175035
- FT-0687984
- A840818
- DTXSID80383560
- MFCD06659058
- 4-(5,5-Dimethyl-1,3,2-dioxaborinan-2-yl)isoquinoline
- Isoquinoline-4-boronic acid 2,2-dimethylpropane-1,3-diol cyclic ester
- Isoquinoline-4-boronic acid 2,2-dimethylpropanediol-1,3 cyclic ester
MDL Number
MFCD06659058
Customs Code
2934999090
FAQ
What are the physical and chemical properties of 4-(5,5-Dimethyl-1,3,2-dioxaborinan-2-yl)isoquinoline (CAS: 844891-01-6)?
4-(5,5-Dimethyl-1,3,2-dioxaborinan-2-yl)isoquinoline is a crystalline solid with a molecular weight of approximately 315.34 g/mol. It has poor water solubility but is soluble in organic solvents like acetone and dichloromethane. The compound shows moderate reactivity, particularly towards nucleophilic substitution reactions. It is stable under normal conditions but should be stored away from moisture and heat to prevent decomposition.
How is 4-(5,5-Dimethyl-1,3,2-dioxaborinan-2-yl)isoquinoline (CAS: 844891-01-6) typically synthesized?
4-(5,5-Dimethyl-1,3,2-dioxaborinan-2-yl)isoquinoline is typically synthesized via a boronate ester formation reaction. The process involves the reaction of isoquinoline with 1,3,2-dioxaborine in the presence of a base and a palladium catalyst. High yield and good selectivity are achievable under optimized conditions, making it a valuable synthetic route in organic synthesis.
What industries use 4-(5,5-Dimethyl-1,3,2-dioxaborinan-2-yl)isoquinoline (CAS: 844891-01-6)?
4-(5,5-Dimethyl-1,3,2-dioxaborinan-2-yl)isoquinoline finds applications in pharmaceuticals, where it serves as a building block for drug synthesis. It is also used in the synthesis of functional polymers for medical devices and sensors. Additionally, it plays a role in semiconductor manufacturing as a precursor for advanced materials.
What precautions should be taken when handling 4-(5,5-Dimethyl-1,3,2-dioxaborinan-2-yl)isoquinoline (CAS: 844891-01-6)?
When handling 4-(5,5-Dimethyl-1,3,2-dioxaborinan-2-yl)isoquinoline, it is essential to wear appropriate personal protective equipment (PPE), including gloves and safety goggles. Work should be conducted in a well-ventilated area or a fume hood to minimize exposure. In case of spill, handle with care and follow the safety data sheet (SDS) recommendations for disposal. Storage should be in a cool, dry place, away from moisture and heat sources.
Related Compounds
![N-(2-Methoxyphenyl)-N-[(4-methylphenyl)sulfonyl]-beta-alanine structure](https://static.chemtradehub.com/structs/103/103687-96-3-8086.webp "N-(2-Methoxyphenyl)-N-[(4-methylphenyl)sulfonyl]-beta-alanine structure")
N-(2-Methoxyphenyl)-N-[(4-methylphenyl)sulfonyl]-beta-alanine
CAS Number:
103687-96-3
Molecular Formula:
C17H19NO5S
![5'-O-[Bis(4-methoxyphenyl)(phenyl)methyl]cytidine structure](https://static.chemtradehub.com/structs/112/112897-99-1-d1f4.webp "5'-O-[Bis(4-methoxyphenyl)(phenyl)methyl]cytidine structure")
5'-O-[Bis(4-methoxyphenyl)(phenyl)methyl]cytidine
CAS Number:
112897-99-1
Molecular Formula:
C30H31N3O7
![(3S,4R)-3-Hydroxy-2,2-dimethyl-4-[(3-oxo-1-cyclopenten-1-yl)oxy]-6-chromanecarbonitrile structure](https://static.chemtradehub.com/structs/121/121055-10-5-583d.webp "(3S,4R)-3-Hydroxy-2,2-dimethyl-4-[(3-oxo-1-cyclopenten-1-yl)oxy]-6-chromanecarbonitrile structure")
(3S,4R)-3-Hydroxy-2,2-dimethyl-4-[(3-oxo-1-cyclopenten-1-yl)oxy]-6-chromanecarbonitrile
CAS Number:
121055-10-5
Molecular Formula:
C17H17NO4
![Methyl 5-chloropyrazolo[1,5-a]pyrimidine-2-carboxylate structure](https://static.chemtradehub.com/structs/126/1263059-26-2-d6da.webp "Methyl 5-chloropyrazolo[1,5-a]pyrimidine-2-carboxylate structure")
Methyl 5-chloropyrazolo[1,5-a]pyrimidine-2-carboxylate
CAS Number:
1263059-26-2
Molecular Formula:
C8H6ClN3O2
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