5-Amino-2-chloro-4-fluorophenol

Basic Information

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CAS Number

84478-72-8

Molecular Formula

C6H5ClFNO

Molecular Weight

161.56 g/mol

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Amines

Fine Chemicals Specialty Chemicals UV Stabilizers

Agricultural Chemicals Pesticides Herbicides

Electronic Chemicals Semiconductor Materials Etchants

Basic Physical Properties

Melting Point

145-146 ºC

Boiling Point

272 ºC

Density

1.519

Flash Point

118 ºC

SMILES

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Nc1cc(O)c(Cl)cc1F

InChI

InChI=1S/C6H5ClFNO/c7-3-1-4(8)5(9)2-6(3)10/h1-2,10H,9H2

InChIKey

AFZLCOLNTRPSIF-UHFFFAOYSA-N

LogP

1.7669

Topological Polar Surface Area

46.25 Å²

Hydrogen Bond Donor/Acceptor

3 / 2

Complexity

124

Safety Information

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Hazard Class

Class IRRITANT Class IRRITANT

Synonyms & References

English

5-amino-2-chloro-4-fluoro-phenol
5-Amino-2-chloro-4-fluorophenol
Phenol,5-amino-2-chloro-4-fluoro-
2-Chloro-4-fluoro-5-aminophenol
2-Fluoro-4-chloro-5-hydroxyaniline
4-Chloro-2-fluoro-5-hydroxyaniline
5-amino-2-chloro-4-fluorobenzenol
Phenol, 5-amino-2-chloro-4-fluoro-
5-amino-2-chloro-4-fiuorophenol
2-Chloro-4-fluoro-5-amino phenol
PubChem4516
Oprea1_398840
3-amino-6-chloro-4-fluorophenol
AFZLCOLNTRPSIF-UHFFFAOYSA-N
WT126
4chloro-2-flu
5-amino-2-chloro-4-fluorophenol

MDL Number

MFCD00055622

Customs Code

2922299090

FAQ

What regulatory guidelines apply to 5-Amino-2-chloro-4-fluorophenol (CAS: 84478-72-8)?

The compound 5-Amino-2-chloro-4-fluorophenol (CAS: 84478-72-8) is subject to various regulatory guidelines. Under the Globally Harmonized System of Classification and Labelling of Chemicals (GHS), it may be classified as a flammable liquid and requires proper hazard communication. In Europe, it is regulated under REACH, which requires suppliers to provide safety data sheets (SDS) and register substances above certain tonnage. Additionally, the FDA and EPA in the USA may regulate its use in pharmaceuticals and pesticides, respectively, requiring compliance with specific documentation and testing requirements.

Are there alternatives to 5-Amino-2-chloro-4-fluorophenol (CAS: 84478-72-8) in synthesis?

Several alternatives to 5-Amino-2-chloro-4-fluorophenol (CAS: 84478-72-8) exist in synthesis. Common alternatives include 4-Chloro-2-fluoroaniline and 2-Chloro-4-fluoroaniline, which offer similar functional groups for various reactions. These alternatives can serve as effective substitutes in different synthetic pathways, depending on the specific requirements of the reaction and the desired product.

What is the market or research trend for 5-Amino-2-chloro-4-fluorophenol (CAS: 84478-72-8)?

The market for 5-Amino-2-chloro-4-fluorophenol (CAS: 84478-72-8) is currently stable, with increasing research interest in its applications as a precursor in pharmaceuticals and agrochemicals. Recent trends indicate a growing focus on developing more sustainable and less toxic alternatives in the field of organic synthesis. The compound's unique chemical structure makes it a valuable intermediate for synthesizing complex molecules, driving further research into its potential uses.

How should waste containing 5-Amino-2-chloro-4-fluorophenol (CAS: 84478-72-8) be handled?

Waste containing 5-Amino-2-chloro-4-fluorophenol (CAS: 84478-72-8) should be managed in accordance with local regulations and safety guidelines. Proper procedures include collecting waste in appropriate containers, ensuring it is free from contaminants, and disposing of it through authorized waste disposal facilities. For hazardous waste, incineration or chemical treatment may be necessary. Employers should adhere to safety precautions, such as using personal protective equipment (PPE) and following proper handling protocols to prevent exposure and environmental contamination.