alpha-Arbutin | CAS No. 84380-01-8

alpha-Arbutin

Basic Information

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CAS Number

84380-01-8

Molecular Formula

C12H16O7

Molecular Weight

272.25 g/mol

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Ethers

Basic Chemical Raw Materials Organic Chemicals Heterocyclic Compounds

Pharmaceutical Chemicals Pharmaceutical Intermediates Heterocyclic Intermediates

Basic Physical Properties

Melting Point

204.0 to 208.0 deg-C

Boiling Point

561.6°C at 760 mmHg

Density

1.556

Flash Point

293.4 °C

Refractive Index

1.65

SMILES

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OC[C@H]1O[C@H](Oc2ccc(O)cc2)[C@H](O)[C@@H](O)[C@@H]1O

InChI

InChI=1S/C12H16O7/c13-5-8-9(15)10(16)11(17)12(19-8)18-7-3-1-6(14)2-4-7/h1-4,8-17H,5H2/t8-,9-,10+,11-,12+/m1/s1

InChIKey

BJRNKVDFDLYUGJ-ZIQFBCGOSA-N

LogP

-1.4291000000000003

Topological Polar Surface Area

119.61000000000001 Å²

Hydrogen Bond Donor/Acceptor

5 / 7

Complexity

279

Safety Information

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Hazard Statement

H302 Harmful if swallowed
Acute toxicity, oral

H315 Causes skin irritation
Skin corrosion/irritation

H319 Causes serious eye irritation
Serious eye damage/eye irritation

H332 Harmful if inhaled
Acute toxicity, inhalation

H335 May cause respiratory irritation
Specific target organ toxicity, single exposure; Respiratory tract irritation

Synonyms & References

English

alpha-Arbutin
4-Hydroquinone-alpha-D-glucopyranoside
a-Arbutin
α-Arbutin
4-Hydroxyphenyl a-D-glucopyranoside
4-Hydroxyphenyl alpha-D-glucopyranoside
4-Hydroxyphenyl α-D-glucopyranoside
alpha-?Arbutin
(2R,3S,4S,5R,6R)-2-(hydroxymethyl)-6-(4-hydroxyphenoxy)oxane-3,4,5-triol
Hydroquinone O-α-D-glucopyranoside
alpha arbutin
PubChem16460
4-Hydroxyphenyl-alpha-D-glucopyranoside
alpha-D-Glucopyranoside, 4-hydroxyphenyl
72VUP07IT5
C12H16O7
alpha-Arbutoside
I+/--Arbutin
4-hydroxyphenyl-D-lucopyranoside
alpha-Arbutin, analytical standard
ZI
4-Hydroxyphenyl α-D-Glucopyranoside

MDL Number

MFCD09838262

Customs Code

2938909090

FAQ

What is alpha-Arbutin (CAS: 84380-01-8)?

Alpha-Arbutin is a glycoside compound with the chemical formula C12H16O7. It is a white to off-white crystalline powder that is commonly used in skin care and pharmaceutical applications. Alpha-Arbutin is known for its mild exfoliating properties and ability to inhibit melanin production, making it a popular ingredient in whitening products. Its structure is similar to hydroquinone but is considered safer due to its natural origin.

What are the main uses of alpha-Arbutin (CAS: 84380-01-8)?

Alpha-Arbutin is widely used in the cosmetic industry as a skin-lightening agent, particularly in topical treatments for hyperpigmentation. It also finds applications in pharmaceuticals for its potential antioxidant and anti-inflammatory properties. Additionally, it is used in food processing as a natural preservative and in research for studying skin health and melanin regulation.

Is alpha-Arbutin (CAS: 84380-01-8) safe?

Alpha-Arbutin is generally considered safe when used in recommended concentrations and under proper conditions. However, it should be handled with care, as high concentrations may cause skin irritation. Safety standards emphasize its lower risk compared to hydroquinone, but users should follow guidelines for proper application and storage to ensure optimal safety.

How should alpha-Arbutin (CAS: 84380-01-8) be stored?

Alpha-Arbutin should be stored in a cool, dry, and dark place to maintain its stability and potency. It is best kept in a sealed container at a temperature below 25°C and away from moisture and direct sunlight. Proper storage helps prevent degradation and ensures the compound remains effective for its intended use.