1-(Imidazo[1,2-a]pyrimidin-2-yl)methanamine

Basic Information

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CAS Number

843609-02-9

Molecular Formula

C7H8N4

Molecular Weight

148.17 g/mol

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Amines

Basic Chemical Raw Materials Organic Chemicals Heterocyclic Compounds

Pharmaceutical Chemicals Pharmaceutical Intermediates Heterocyclic Intermediates

Basic Physical Properties

Physical State

OFF-WHITE SOLID

SMILES

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NCc1cn2cccnc2n1

InChI

InChI=1S/C7H8N4/c8-4-6-5-11-3-1-2-9-7(11)10-6/h1-3,5H,4,8H2

InChIKey

PFJRNIUANBPJHS-UHFFFAOYSA-N

LogP

0.18799999999999994

Topological Polar Surface Area

56.21 Å²

Hydrogen Bond Donor/Acceptor

2 / 4

Complexity

138

Safety Information

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GHS Hazard Pictograms

H314

Hazard Statement

H314 Causes severe skin burns and eye damage
Skin corrosion/irritation

Hazard Class

Class IRRITANT Class IRRITANT

Synonyms & References

English

Imidazo[1,2-a]pyrimidin-2-ylmethanamine
1-Imidazo[1,2-a]pyrimidin-2-ylmethanamine dihydrochloride
IMIDAZO[1,2-A]PYRIMIDIN-2-YL-METHYLAMINE,
Imidazo[1,2-a]pyrimidine-2-methanamine
(imidazo[1,2-a]pyrimidin-2-ylmethyl)amine(SALTDATA: 1.95HCl H2O)
C-IMIDAZO[1,2-A]PYRIMIDIN-2-YL-METHYLAMINE
1-Imidazo[1,2-a]pyrimidin-2-ylmethanamine
2-AMINOMETHYLIMIDAZO[1,2-A]PYRIMIDINE
1-Imidazo[1,2-a]pyrimidin-2-ylmethanaminedihydrochloride
PFJRNIUANBPJHS-UHFFFAOYSA-N
STK897768
SBB047475
AB26753
AB002694
Imidazo[1,2-a]pyrimidin-2-yl-methylamine

MDL Number

MFCD06660691

Customs Code

2933990090

FAQ

What are the physical and chemical properties of 1-(Imidazo[1,2-a]pyrimidin-2-yl)methanamine (CAS: 843609-02-9)?

1-(Imidazo[1,2-a]pyrimidin-2-yl)methanamine is a solid compound at room temperature. Its molecular weight is approximately 236.25 g/mol. The compound has low solubility in water but is soluble in organic solvents such as ethanol and dimethylformamide. It is known to be relatively stable under normal conditions but may react with strong acids and bases. Its reactivity can be influenced by pH and temperature.

How is 1-(Imidazo[1,2-a]pyrimidin-2-yl)methanamine (CAS: 843609-02-9) typically synthesized?

1-(Imidazo[1,2-a]pyrimidin-2-yl)methanamine is typically synthesized via a multi-step process involving condensation reactions. Common methods include using imidazo[1,2-a]pyrimidine and methylamine in the presence of a catalyst like sodium hydride. The reaction is performed under anhydrous conditions and requires precise temperature control to achieve high selectivity and yield.

What industries use 1-(Imidazo[1,2-a]pyrimidin-2-yl)methanamine (CAS: 843609-02-9)?

1-(Imidazo[1,2-a]pyrimidin-2-yl)methanamine finds application in several industries. It is primarily used in the pharmaceutical industry for the synthesis of various bioactive compounds. Additionally, it has potential applications in the polymer industry for the development of advanced materials, and in the sensor industry for its sensitivity to certain chemical and biological analytes.

What precautions should be taken when handling 1-(Imidazo[1,2-a]pyrimidin-2-yl)methanamine (CAS: 843609-02-9)?

When handling 1-(Imidazo[1,2-a]pyrimidin-2-yl)methanamine, it is essential to wear appropriate personal protective equipment (PPE) including gloves, safety goggles, and a lab coat. Work should be conducted in a well-ventilated area or a fume hood. Spills should be cleaned up immediately using appropriate absorbent materials. Always refer to the Material Safety Data Sheet (MSDS) for detailed safety information and emergency procedures.