1-(5-Bromo-6-methoxy-2-naphthyl)ethanone

Basic Information

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CAS Number

84167-74-8

Molecular Formula

C13H11BrO2

Molecular Weight

279.13 g/mol

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Carboxylic Acids

Basic Chemical Raw Materials Organic Chemicals Ketones

Basic Chemical Raw Materials Organic Chemicals Ethers

Fine Chemicals Dyes and Pigments Organic Dyes

Fine Chemicals Surfactants Anionic Surfactants

Agricultural Chemicals Pesticides Herbicides

Basic Physical Properties

Boiling Point

389.0±22.0 °C at 760 mmHg

Density

1.4±0.1 g/cm3

Flash Point

189.1±22.3 °C

Refractive Index

1.618

Vapor Pressure

0.0±0.9 mmHg at 25°C

SMILES

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CC(=O)C1=CC2=C(C=C1)C(=C(C=C2)OC)Br

InChI

InChI=1S/C13H11BrO2/c1-8(15)9-3-5-11-10(7-9)4-6-12(16-2)13(11)14/h3-7H,1-2H3

InChIKey

KDDYYAXVVDTNND-UHFFFAOYSA-N

LogP

3.813500000000002

Topological Polar Surface Area

26.3 Å²

Hydrogen Bond Donor/Acceptor

0 / 2

Complexity

267

Synonyms & References

English

AKOS004902246
CS-0204960
SCHEMBL7736295
1-(5-Bromo-6-methoxy-2-naphthyl)ethanone
DTXSID90347496
84167-74-8
SY054281
6-Acetyl-1-bromo-2-methoxynaphthalene
AC-9096
1-(5-Bromo-6-methoxy-2-naphthyl)ethanone #
2-Acetyl-5-bromo-6-methoxy-naphthalene
1-(5-bromo-6-methoxynaphthalen-2-yl)ethanone
DIETHYLISOBUTYLIDENEMALONATE
Ethanone, 1-(5-bromo-6-methoxy-2-naphthyl)-
1-(5-bromo-6-methoxynaphthalen-2-yl)ethan-1-one
MFCD00100832
FT-0641942
2-ACETYL-5-BROMO-6-METHOXYNAPHTHALENE
5-bromo-6-methoxy-2-acetylnaphthalene
5'-Bromo-6'-methoxy-2'-acetonaphthone
AS-30227
Ethanone, 1-(5-bromo-6-methoxy-2-naphthalenyl)-
2-Acetyl-5-Bromo-6-Methoxynaphthalene
2-Aceryl-5-Bromo-6-Methoxynaphthalene
2-ACETYL-5-BROMO-6 METHOXY NAPHTHALENE
KDDYYAXVVDTNND-UHFFFAOYSA-N
VZ23477
1-(5-Bromo-6-metho

MDL Number

MFCD00100832

Customs Code

2914700090

FAQ

What are the physical and chemical properties of 1-(5-Bromo-6-methoxy-2-naphthyl)ethanone (CAS: 84167-74-8)?

1-(5-Bromo-6-methoxy-2-naphthyl)ethanone is a white crystalline solid with a molecular weight of approximately 300 g/mol. It has a melting point of around 60-62°C and is slightly soluble in water but more soluble in organic solvents. This compound is less reactive under normal conditions but can undergo nucleophilic substitution reactions. Its stability under various conditions makes it suitable for use in organic synthesis and pharmaceutical applications.

How is 1-(5-Bromo-6-methoxy-2-naphthyl)ethanone (CAS: 84167-74-8) typically synthesized?

1-(5-Bromo-6-methoxy-2-naphthyl)ethanone is typically synthesized via a Friedel-Crafts acylation reaction. The process involves the acylation of 5-bromo-6-methoxy-2-naphthylmethanol using acetic anhydride in the presence of anhydrous aluminum chloride as a catalyst. The reaction yields the desired compound with good selectivity and high yield.

What industries use 1-(5-Bromo-6-methoxy-2-naphthyl)ethanone (CAS: 84167-74-8)?

1-(5-Bromo-6-methoxy-2-naphthyl)ethanone (CAS: 84167-74-8) is primarily used in the pharmaceutical and chemical industries. It serves as a key intermediate in the synthesis of various drugs and is also used in the preparation of dyes and other organic compounds. Its application in semiconductor materials and sensors is also explored due to its unique chemical properties.

What precautions should be taken when handling 1-(5-Bromo-6-methoxy-2-naphthyl)ethanone (CAS: 84167-74-8)?

When handling 1-(5-Bromo-6-methoxy-2-naphthyl)ethanone (CAS: 84167-74-8), it is essential to wear appropriate personal protective equipment (PPE) including gloves, goggles, and a lab coat. Work should be conducted in a well-ventilated area or a fume hood to avoid inhalation. Spills should be cleaned up carefully, and the material safety data sheet (MSDS) should be consulted for specific instructions. Ensure proper storage in a cool, dry place away from direct sunlight and flammable materials.