1-(Diphenylmethyl)piperazine

Basic Information

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CAS Number

841-77-0

Molecular Formula

C17H20N2

Molecular Weight

252.36 g/mol

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Heterocyclic Compounds

Pharmaceutical Chemicals Pharmaceutical Intermediates Heterocyclic Intermediates

Basic Physical Properties

Physical State

Powder

Melting Point

91.0 to 95.0 deg-C

Boiling Point

185°C/2mmHg

Density

1.0546 (rough estimate)

Water Solubility

0.45 g/L (20 ºC)

Flash Point

115 ºC

Refractive Index

1.5794 (estimate)

SMILES

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N1(C(C2=CC=CC=C2)C3=CC=CC=C3)CCNCC1

InChI

InChI=1S/C17H20N2/c1-3-7-15(8-4-1)17(16-9-5-2-6-10-16)19-13-11-18-12-14-19/h1-10,17-18H,11-14H2

InChIKey

NWVNXDKZIQLBNM-UHFFFAOYSA-N

LogP

2.6812000000000005

Topological Polar Surface Area

15.27 Å²

Hydrogen Bond Donor/Acceptor

1 / 2

Complexity

230

Safety Information

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Hazard Statement

H302 Harmful if swallowed
Acute toxicity, oral

H315 Causes skin irritation
Skin corrosion/irritation

H319 Causes serious eye irritation
Serious eye damage/eye irritation

Hazard Class

Class IRRITANT Class IRRITANT

Sensitiveness

Air Sensitive

Synonyms & References

English

1-Benzhydrylpiperazine
Benzhydrylpiperazine
N-(Diphenylmethyl)piperazine
1-(Diphenylmethyl)piperazine
1-Benzhydryl-piperazine
N-Benzhydrylpiperazine
Diphenylmethylpiperazine
Norcyclizine
Normethylcyclizine
Piperazine, 1-(diphenylmethyl)-
4-Benzhydrylpiperazine
benzhydryl piperazine
(diphenylmethyl)piperazine
1-(diphenylmethyl) piperazine
NWVNXDKZIQLBNM-UHFFFAOYSA-N
CINNARIZINE IMPURITY A
benzhydrylpiperazin
1-benzh
Cetirizine SM impurity 1 HCl
1-benzhydrylpiperazine

MDL Number

MFCD00038379

Customs Code

2942000000

FAQ

What is 1-(Diphenylmethyl)piperazine (CAS: 841-77-0)?

1-(Diphenylmethyl)piperazine (CAS: 841-77-0) is a piperazine derivative with the chemical formula C18H20N2. It is a colorless crystalline solid with a faint amine odor, known for its stability and solubility in organic solvents. This compound is widely used in the synthesis of various pharmaceuticals and organic chemicals due to its versatile chemical structure.

What are the main uses of 1-(Diphenylmethyl)piperazine (CAS: 841-77-0)?

1-(Diphenylmethyl)piperazine (CAS: 841-77-0) is primarily used in the pharmaceutical industry as an intermediate in the synthesis of drugs, including sedatives and antidepressants. It also finds applications in organic synthesis, chemical research, and as a building block for developing new materials and compounds with specific functional properties.

Is 1-(Diphenylmethyl)piperazine (CAS: 841-77-0) safe?

1-(Diphenylmethyl)piperazine (CAS: 841-77-0) is generally considered safe when handled properly. However, it may cause skin and eye irritation. Safety precautions include using personal protective equipment (PPE) such as gloves and goggles, and ensuring proper ventilation. It should be stored in a secure, well-ventilated area away from incompatible substances.

How should 1-(Diphenylmethyl)piperazine (CAS: 841-77-0) be stored?

1-(Diphenylmethyl)piperazine (CAS: 841-77-0) should be stored in a cool, dry, and dark place, preferably at 2-8°C. It is stable under these conditions and should be kept in a tightly sealed container to prevent moisture and air exposure. Avoid storing near strong oxidizers or acids to maintain its chemical integrity.