(S)-Ropivacaine

Basic Information

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CAS Number

84057-95-4

Molecular Formula

C17H26N2O

Molecular Weight

274.41 g/mol

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Carboxylic Acids

Basic Chemical Raw Materials Organic Chemicals Heterocyclic Compounds

Pharmaceutical Chemicals Pharmaceutical Intermediates Heterocyclic Intermediates

Fine Chemicals Dyes and Pigments Organic Dyes

Fine Chemicals Surfactants Anionic Surfactants

Basic Physical Properties

Melting Point

144-151°C

Boiling Point

98°C at 13.5018 mmHg

Density

Refractive Index

1.55

Specific Rotation

-80° ~ -82°(c=2, in methanol)

SMILES

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CCCN1CCCCC1C(=O)NC2=C(C=CC=C2C)C

InChI

InChI=1S/C17H26N2O/c1-4-11-19-12-6-5-10-15(19)17(20)18-16-13(2)8-7-9-14(16)3/h7-9,15H,4-6,10-12H2,1-3H3,(H,18,20)/t15-/m0/s1

InChIKey

ZKMNUMMKYBVTFN-HNNXBMFYSA-N

LogP

3.5064400000000013

pKa

8.16(at 25℃)

Topological Polar Surface Area

32.34 Å²

Hydrogen Bond Donor/Acceptor

1 / 3

Complexity

308

Safety Information

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Hazard Statement

H302 Harmful if swallowed
Acute toxicity, oral

H315 Causes skin irritation
Skin corrosion/irritation

H319 Causes serious eye irritation
Serious eye damage/eye irritation

H335 May cause respiratory irritation
Specific target organ toxicity, single exposure; Respiratory tract irritation

Synonyms & References

English

Ropivacaine hydrochloride
Naropin (TN)
Ropivacainum (INN-Latin)
Q-201677
CS-0009514
ROPIVACAINE (USP-RS)
A840710
ROPIVACAINE [MI]
TLC-590
ZKMNUMMKYBVTFN-HNNXBMFYSA-N
SCHEMBL33292
(s)-n-(2,6-dimethylphenyl)-1-propyl-2-piperidinecarboxamide
Ropivacaina [INN-Spanish]
AKOS017343283
HY-B0563
R0251
DTXSID4040187
(2S)-N-(2,6-dimethylphenyl)-1-propylpiperidine-2-carboxamide
Q279504
(-)-1-Propyl-2',6'-dimethyl-2-piperidylcarboxyanilid
C07532
UNII-7IO5LYA57N
(2S)-N-(2,6-dimethylphenyl)-1-propyl-piperidine-2-carboxamide
84057-95-4
CHEBI:8890
DTXCID2020187
(-)-1-propyl-2',6'-dimethyl-2-piperidylcarboxyanilide
1 Propyl 2',6' pipecoloxylidide
(S)-N-(2,6-Dimethylphenyl)-1-propylpiperidine-2-carboxamide
2-Piperidinecarboxamide, N-(2,6-dimethylphenyl)-1-propyl-, (2S)-
(S)-Ropivacaine

MDL Number

MFCD00864425

Customs Code

2933399090

FAQ

What is (S)-Ropivacaine (CAS: 84057-95-4)?

(S)-Ropivacaine is a long-acting local anesthetic used in medical procedures to numb pain in specific areas of the body. Its chemical formula is C16H27NO2. It is optically active and has a higher lipophilicity compared to levobupivacaine, making it suitable for various regional and epidural anesthesia applications.

What are the main uses of (S)-Ropivacaine (CAS: 84057-95-4)?

(S)-Ropivacaine is primarily used in medical procedures as a local anesthetic. It is commonly applied for pain management in regional anesthesia, such as spinal, epidural, and peripheral nerve blocks. It is also used for infiltration anesthesia and local block anesthesia in surgery and postoperative pain management.

Is (S)-Ropivacaine (CAS: 84057-95-4) safe?

(S)-Ropivacaine is generally safe when used under medical supervision. However, it is important to follow safety guidelines, including proper dosage and administration techniques. Adverse reactions include systemic toxicity, which can be mitigated by avoiding intravascular injection. Always store the compound securely and follow safety standards.

How should (S)-Ropivacaine (CAS: 84057-95-4) be stored?

(S)-Ropivacaine should be stored in a cool, dry place away from direct sunlight and heat sources. Maintain a temperature range of 15-25°C (59-77°F) and store in a tightly sealed container to prevent moisture absorption. Avoid exposure to excessive humidity and light, as these can affect the stability of the compound. Keep the substance away from children and unauthorized personnel. Handle with care to prevent accidental spills or ingestion. Store out of reach of pets.