3'-Cytidylic acid

Basic Information

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CAS Number

84-52-6

Molecular Formula

C9H14N3O8P

Molecular Weight

323.2 g/mol

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Carboxylic Acids

Basic Chemical Raw Materials Organic Chemicals Ethers

Basic Chemical Raw Materials Organic Chemicals Amines

Basic Chemical Raw Materials Organic Chemicals Heterocyclic Compounds

Pharmaceutical Chemicals Pharmaceutical Intermediates Heterocyclic Intermediates

Fine Chemicals Dyes and Pigments Organic Dyes

Agricultural Chemicals Pesticides Insecticides

Basic Physical Properties

Melting Point

230 °C

SMILES

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c1cn(c(=O)nc1N)[C@H]2[C@@H]([C@@H]([C@H](O2)CO)OP(=O)(O)O)O

InChI

InChI=1S/C9H14N3O8P/c10-5-1-2-12(9(15)11-5)8-6(14)7(4(3-13)19-8)20-21(16,17)18/h1-2,4,6-8,13-14H,3H2,(H2,10,11,15)(H2,16,17,18)/t4-,6-,7-,8-/m1/s1

InChIKey

UOOOPKANIPLQPU-XVFCMESISA-N

LogP

-2.446

pKa

0.8, 4.28, 6.0(at 25℃)

Topological Polar Surface Area

177.35999999999999 Å²

Hydrogen Bond Donor/Acceptor

6 / 11

Complexity

520

Synonyms & References

English

3'-Cytidylic acid
Cytidine 3'(2’)-Monophosphate
CYTIDINE 3'-MONOPHOSPHATE
Cytidine-3'-monophosphate
CYTIDINE-3'-MONOPHOSPHATE(AS)
3'-CMP
3'-cytidine monophosphate
3'-Cytosylic acid
Citidine 3'-phosphate
Cytidilic acid b
CYTIDINE 3
CYTIDINE 3'-MONOPHOS
Cytidine 3'-phosphate
Cytidine 3’-monophosphate

MDL Number

MFCD00006543

Customs Code

2934999090

FAQ

What are the physical and chemical properties of 3'-Cytidylic acid (CAS: 84-52-6)?

3'-Cytidylic acid (CAS: 84-52-6) is a white, crystalline solid with a molecular weight of approximately 266.21 g/mol. It is poorly soluble in water but soluble in ethanol. The acid is relatively stable under normal conditions but is reactive under basic conditions. It is often used in nucleotide chemistry and biological research.

How is 3'-Cytidylic acid (CAS: 84-52-6) typically synthesized?

3'-Cytidylic acid can be synthesized through the condensation of cytidine with phosphate in the presence of a base, such as sodium hydroxide. The reaction is typically carried out in an aqueous medium, and the product is purified by chromatography. This method achieves a yield of about 70-80%.

What industries use 3'-Cytidylic acid (CAS: 84-52-6)?

3'-Cytidylic acid (CAS: 84-52-6) is primarily used in the pharmaceutical industry for the synthesis of nucleoside analogs and antiviral drugs. It also finds applications in biotechnology, where it is used in nucleic acid research and as a building block for oligonucleotide synthesis.

What precautions should be taken when handling 3'-Cytidylic acid (CAS: 84-52-6)?

When handling 3'-Cytidylic acid (CAS: 84-52-6), it is essential to wear appropriate personal protective equipment (PPE) such as gloves, goggles, and a lab coat. The compound should be used in a well-ventilated area or with a fume hood. In case of a spill, it should be contained and disposed of according to local regulations. Always refer to the Safety Data Sheet (SDS) for specific handling and disposal instructions.