![N-[(3S)-1-(Dimethylcarbamoyl)-3-pyrrolidinyl]-5-[(Z)-(5-fluoro-2-oxo-1,2-dihydro-3H-indol-3-ylidene)methyl]-2,4-dimethyl-1H-pyrrole-3-carboxamide structure](https://static.chemtradehub.com/structs/101/1013920-15-4-a4c8.webp "N-[(3S)-1-(Dimethylcarbamoyl)-3-pyrrolidinyl]-5-[(Z)-(5-fluoro-2-oxo-1,2-dihydro-3H-indol-3-ylidene)methyl]-2,4-dimethyl-1H-pyrrole-3-carboxamide structure")
N-[(3S)-1-(Dimethylcarbamoyl)-3-pyrrolidinyl]-5-[(Z)-(5-fluoro-2-oxo-1,2-dihydro-3H-indol-3-ylidene)methyl]-2,4-dimethyl-1H-pyrrole-3-carboxamide
CAS Number:
1013920-15-4
Molecular Formula:
C23H26FN5O3
2-(1,2,3,4-Tetrahydro-1-naphthalenyl)-4,5-dihydro-1H-imidazole | CAS No. 84-22-0
2-(1,2,3,4-Tetrahydro-1-naphthalenyl)-4,5-dihydro-1H-imidazole
Basic Information
CAS Number
84-22-0
Molecular Formula
C13H16N2
Molecular Weight
200.29 g/mol
AD
Basic Physical Properties
Boiling Point
393.5 °C at 760 mmHg
Density
1.2
Flash Point
191.8 °C
Refractive Index
1.656
Synonyms & References
English
- Tetrahydrozoline
- 2-(1,2,3,4-tetrahydronaphthalen-1-yl)-4,5-dihydro-1H-imidazole
- TETRYZOLINE
- 2-tetralin-1-yl-4,5-dihydro-1H-imidazole
- Tetrahydrozolinum
- Tetryzolin
- Tyzanol
- 4,5-Dihydro-2-(1,2,3,4-tetrahydro-1-naphthyl)-1H-imidazole
- Visine
MDL Number
MFCD00216026
FAQ
What are the physical and chemical properties of 2-(1,2,3,4-Tetrahydro-1-naphthalenyl)-4,5-dihydro-1H-imidazole (CAS: 84-22-0)?
2-(1,2,3,4-Tetrahydro-1-naphthalenyl)-4,5-dihydro-1H-imidazole (CAS: 84-22-0) is a crystalline solid with a molecular weight of approximately 268.31 g/mol. It has a low solubility in water but is more soluble in organic solvents like ethanol and acetone. Chemically, it is highly reactive, particularly towards nucleophiles and reducing agents. It is used in various synthetic applications due to its chemical versatility.
How is 2-(1,2,3,4-Tetrahydro-1-naphthalenyl)-4,5-dihydro-1H-imidazole (CAS: 84-22-0) typically synthesized?
2-(1,2,3,4-Tetrahydro-1-naphthalenyl)-4,5-dihydro-1H-imidazole is typically synthesized through a multistep process involving the coupling of 1-naphthylamine with 1,2,3,4-tetrahydro-1-naphthol in the presence of a catalytic amount of a suitable base. The reaction is carried out in an aprotic solvent such as dimethylformamide (DMF) at elevated temperatures. The yield can be improved by using a palladium catalyst and optimizing reaction conditions.
What industries use 2-(1,2,3,4-Tetrahydro-1-naphthalenyl)-4,5-dihydro-1H-imidazole (CAS: 84-22-0)?
2-(1,2,3,4-Tetrahydro-1-naphthalenyl)-4,5-dihydro-1H-imidazole (CAS: 84-22-0) is used in industries such as pharmaceuticals, where it serves as a key intermediate in the synthesis of various drugs. It also finds applications in the development of sensors and semiconductor materials due to its unique electronic properties.
What precautions should be taken when handling 2-(1,2,3,4-Tetrahydro-1-naphthalenyl)-4,5-dihydro-1H-imidazole (CAS: 84-22-0)?
When handling 2-(1,2,3,4-Tetrahydro-1-naphthalenyl)-4,5-dihydro-1H-imidazole (CAS: 84-22-0), it is essential to wear appropriate personal protective equipment (PPE), including gloves and safety goggles. The reaction should be performed in a well-ventilated area or a fume hood. Spills should be handled with caution using a spill kit, and any waste should be disposed of according to local regulations. Always consult the Safety Data Sheet (SDS) for more detailed handling instructions.
Related Compounds
![7-Methylpyrazolo[1,5-a]pyrimidine-3-carboxylic acid structure](https://static.chemtradehub.com/structs/101/1016505-59-1-4c54.webp "7-Methylpyrazolo[1,5-a]pyrimidine-3-carboxylic acid structure")
7-Methylpyrazolo[1,5-a]pyrimidine-3-carboxylic acid
CAS Number:
1016505-59-1
Molecular Formula:
C8H7N3O2
![2-Fluoro-6-({[(2-methyl-2-propanyl)oxy]carbonyl}amino)benzoic acid structure](https://static.chemtradehub.com/structs/104/1048919-15-8-ba81.webp "2-Fluoro-6-({[(2-methyl-2-propanyl)oxy]carbonyl}amino)benzoic acid structure")
2-Fluoro-6-({[(2-methyl-2-propanyl)oxy]carbonyl}amino)benzoic acid
CAS Number:
1048919-15-8
Molecular Formula:
C12H14FNO4
1,5,8-Trihydroxy-3-methoxy-2-(3-methyl-2-buten-1-yl)-9H-xanthen-9-one
CAS Number:
110187-11-6
Molecular Formula:
C19H18O6
![9-Benzyl-2,9-diazaspiro[5.5]undecane dihydrochloride structure](https://static.chemtradehub.com/structs/119/1198286-24-6-4781.webp "9-Benzyl-2,9-diazaspiro[5.5]undecane dihydrochloride structure")
9-Benzyl-2,9-diazaspiro[5.5]undecane dihydrochloride
CAS Number:
1198286-24-6
Molecular Formula:
C16H26Cl2N2
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