Compound Q&A

How is 2-(1,2,3,4-Tetrahydro-1-naphthalenyl)-4,5-dihydro-1H-imidazole (CAS: 84-22-0) typically synthesized?

Answer

2-(1,2,3,4-Tetrahydro-1-naphthalenyl)-4,5-dihydro-1H-imidazole
2-(1,2,3,4-Tetrahydro-1-naphthalenyl)-4,5-dihydro-1H-imidazole is typically synthesized through a multistep process involving the coupling of 1-naphthylamine with 1,2,3,4-tetrahydro-1-naphthol in the presence of a catalytic amount of a suitable base. The reaction is carried out in an aprotic solvent such as dimethylformamide (DMF) at elevated temperatures. The yield can be improved by using a palladium catalyst and optimizing reaction conditions.

About

CAS No 84-22-0
English Name 2-(1,2,3,4-Tetrahydro-1-naphthalenyl)-4,5-dihydro-1H-imidazole
Molecular Formula C13H16N2
Molecular Weight 200.29 g/mol
SMILES C1CN=C(N1)C2CCCc3ccccc23
InChIKey BYJAVTDNIXVSPW-UHFFFAOYSA-N
Last Updated: 2025-11-01 22:12

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