Azithromycin | CAS No. 83905-01-5

Azithromycin

Basic Information

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CAS Number

83905-01-5

Molecular Formula

C38H72N2O12

Molecular Weight

749 g/mol

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Carboxylic Acids

Basic Chemical Raw Materials Organic Chemicals Esters

Basic Chemical Raw Materials Organic Chemicals Ethers

Basic Chemical Raw Materials Organic Chemicals Heterocyclic Compounds

Pharmaceutical Chemicals Pharmaceutical Intermediates Heterocyclic Intermediates

Fine Chemicals Surfactants Anionic Surfactants

Polymers and Plastics Thermoplastics Polyolefins

Laboratory Chemicals Research Chemicals Biochemical Reagents

Basic Physical Properties

Melting Point

113-115 ºC

Boiling Point

822.1±65.0°C at 760 mmHg

Density

1.2±0.1 g/cm3

Flash Point

451.0±34.3 °C

Solubility

soluble in ethanol and DSMO, minimally soluble in water

Refractive Index

1.536

Vapor Pressure

2.65X10-24 mm Hg at 25 °C (est)

Specific Rotation

D20 -37° (c = 1 in CHCl3)

SMILES

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CCC1C(C(C(N(CC(CC(C(C(C(C(C(=O)O1)C)OC2CC(C(C(O2)C)O)(C)OC)C)OC3C(C(CC(O3)C)N(C)C)O)(C)O)C)C)C)O)(C)O

InChI

InChI=1S/C38H72N2O12/c1-15-27-38(10,46)31(42)24(6)40(13)19-20(2)17-36(8,45)33(52-35-29(41)26(39(11)12)16-21(3)48-35)22(4)30(23(5)34(44)50-27)51-28-18-37(9,47-14)32(43)25(7)49-28/h20-33,35,41-43,45-46H,15-19H2,1-14H3/t20-,21-,22+,23-,24-,25+,26+,27-,28+,29-,30+,31-,32+,33-,35+,36-,37-,38-/m1/s1

InChIKey

MQTOSJVFKKJCRP-BICOPXKESA-N

LogP

1.9007000000000054

Topological Polar Surface Area

180.07999999999998 Å²

Hydrogen Bond Donor/Acceptor

5 / 14

Complexity

1150

Safety Information

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Hazard Statement

H317 May cause an allergic skin reaction
Sensitization, Skin

H334 May cause allergy or asthma symptoms or breathing difficulties if inhaled
Sensitization, respiratory

Stability

Stable. Incompatible with strong oxidizing agents.

Synonyms & References

English

Azithromycin for peak identification, European Pharmacopoeia (EP) Reference Standard
[2R-(2R*,3S*,4R*,5R*,8R*,10R*,11R*,12S*,13S*,14R*)]-13-[(2,6-Dideoxy-3-C-methyl-3-O-methyl-.alpha.-L-ribo-hexopyranosyl)oxy]-2-ethyl-3,4,10-trihydroxy-3,5,6,8,10,12,14-heptamethyl-11-[[3,4,6-
Azithromycin, Antibiotic for Culture Media Use Only
C38H72N2O12
Azitrocin
CP-62,993
N-methyl-11-aza-10-deoxy-10-dihydroerythromycin A
AZITHROMYCIN DIHYDRATE
Azithromycin for system suitability, European Pharmacopoeia (EP) Reference Standard
NCGC00090753-04
UNII-J2KLZ20U1M
HMS2232M10
1-Oxa-6-azacyclopentadecan-15-one, 13-((2,6-dideoxy-3-C-methyl-3-O-methyl-alpha-L-ribo-hexopyranosyl)oxy)-2-ethyl-3,4,10-trihydroxy-3,5,6,8,10,12,14-heptamethyl-11-((3,4,6-trideoxy-3-(dimethylamino)-beta-D-xylo-hexopyranosyl)oxy)-, (2R,3S,4R,5R,8R,10R,11R,12S,13S,14R)-
XZ-450
Anhydrous azithromycin
CHEMBL529
DivK1c_000233
Azithromycin, European Pharmacopoeia (EP) Reference Standard
AZM
Tox21_201011
Mixoterin
Xithrone
Spectrum2_001582
MLS001201763
NSC643732
Azitromicina
EC 617-500-5
Azithromycinum [Latin]
CP 62993
Aritromicina [Spanish]
NCGC00090753-03

MDL Number

MFCD03266623

Customs Code

2941500000

FAQ

What is Azithromycin (CAS: 83905-01-5)?

Azithromycin, with CAS number 83905-01-5, is a macrolide antibiotic used to treat bacterial infections. Its chemical formula is C38H68N2O12. It is a white to off-white powder with good solubility in water. Azithromycin works by inhibiting protein synthesis in bacteria, making it effective against a wide range of gram-positive and gram-negative organisms. It is commonly prescribed for respiratory and skin infections.

What are the main uses of Azithromycin (CAS: 83905-01-5)?

Azithromycin (CAS: 83905-01-5) is primarily used in the treatment of bacterial infections, including respiratory tract infections, skin infections, and sexually transmitted diseases. It is also used in veterinary medicine and as a prophylactic agent. Due to its broad spectrum of activity, azithromycin is widely prescribed in clinical settings. Its applications extend to research for developing new antimicrobial agents and formulations.

Is Azithromycin (CAS: 83905-01-5) safe?

Azithromycin (CAS: 83905-01-5) is generally considered safe when used as directed. It is well-tolerated by most patients, though side effects such as gastrointestinal discomfort may occur. Handling precautions should be taken to avoid direct contact with the powder, and protective gloves are recommended during preparation. Safety standards ensure its proper use in medical and industrial contexts.

How should Azithromycin (CAS: 83905-01-5) be stored?

Azithromycin (CAS: 83905-01-5) should be stored in a cool, dry place away from moisture and light. It is typically kept in a sealed container at a temperature between 15°C to 30°C. Proper storage ensures stability and effectiveness of the compound. Avoid exposure to high humidity or extreme temperatures to prevent degradation.