(2E,6Z,8E,10E)-N-(2-Hydroxy-2-methylpropyl)-2,6,8,10-dodecatetraenamide | CAS No. 83883-10-7

(2E,6Z,8E,10E)-N-(2-Hydroxy-2-methylpropyl)-2,6,8,10-dodecatetraenamide

Basic Information

CAS Number

83883-10-7

Molecular Formula

C16H25NO2

Molecular Weight

263.38 g/mol

AD

Basic Physical Properties

Solubility

Methanol,DMF

C/C=C/C=C/C=C\CC/C=C/C(=O)NCC(C)(C)O

InChI

InChI=1S/C16H25NO2/c1-4-5-6-7-8-9-10-11-12-13-15(18)17-14-16(2,3)19/h4-9,12-13,19H,10-11,14H2,1-3H3,(H,17,18)/b5-4+,7-6+,9-8-,13-12+

InChIKey

LHFKHAVGGJJQFF-UEOYEZOQSA-N

LogP

2.898400000000001

Topological Polar Surface Area

49.33 Ų

Hydrogen Bond Donor/Acceptor

2 / 3

Complexity

363

Safety Information

View Safety Information

Storage Conditions

-20℃

Synonyms & References

English

  • (2E,6Z,8E,10E)-N-(2-Hydroxy-2-methylpropyl)dodeca-2,6,8,10-tetraenamide
  • (2E,6Z,8E,10E)-N-(2-Hydroxy-2-methylpropyl)dodeca-2,6,8,10-tetraemide
  • alpha-Hydroxy-Sanshool
  • Hydroxy-α-sanshool

MDL Number

MFCD17779317

FAQ

What are the physical and chemical properties of (2E,6Z,8E,10E)-N-(2-Hydroxy-2-methylpropyl)-2,6,8,10-dodecatetraenamide (CAS: 83883-10-7)?

The compound (2E,6Z,8E,10E)-N-(2-Hydroxy-2-methylpropyl)-2,6,8,10-dodecatetraenamide (CAS: 83883-10-7) is a crystalline solid with a molecular weight of approximately 356.5 g/mol. It is poorly soluble in water but soluble in organic solvents like methanol and ethanol. The compound exhibits moderate reactivity towards nucleophiles. It is stable under normal conditions but may degrade when exposed to strong acids or bases.

How is (2E,6Z,8E,10E)-N-(2-Hydroxy-2-methylpropyl)-2,6,8,10-dodecatetraenamide (CAS: 83883-10-7) typically synthesized?

The compound (2E,6Z,8E,10E)-N-(2-Hydroxy-2-methylpropyl)-2,6,8,10-dodecatetraenamide (CAS: 83883-10-7) is synthesized via a multi-step process involving the reaction of a dodecatrienamide with a 2-hydroxy-2-methylpropylamine under basic conditions. The reaction is catalyzed by a mild base such as triethylamine, and the yield is around 70-75%. The purity is ensured through recrystallization and chromatographic purification.

What industries use (2E,6Z,8E,10E)-N-(2-Hydroxy-2-methylpropyl)-2,6,8,10-dodecatetraenamide (CAS: 83883-10-7)?

The compound (2E,6Z,8E,10E)-N-(2-Hydroxy-2-methylpropyl)-2,6,8,10-dodecatetraenamide (CAS: 83883-10-7) is primarily used in the pharmaceutical industry for its anti-inflammatory and analgesic properties. It also finds applications in the polymer industry for its potential as a monomer and in the development of smart materials. Additionally, it is used in the production of sensors and semiconductors due to its unique optical and electronic properties.

What precautions should be taken when handling (2E,6Z,8E,10E)-N-(2-Hydroxy-2-methylpropyl)-2,6,8,10-dodecatetraenamide (CAS: 83883-10-7)?

When handling (2E,6Z,8E,10E)-N-(2-Hydroxy-2-methylpropyl)-2,6,8,10-dodecatetraenamide (CAS: 83883-10-7), it is essential to wear appropriate personal protective equipment (PPE) such as gloves, goggles, and a lab coat. Work should be conducted in a well-ventilated area or a fume hood to minimize inhalation risks. Spills should be carefully cleaned up using appropriate absorbents. For detailed safety information, refer to the Safety Data Sheet (SDS) for the compound.

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