Compound Q&A

How is (2E,6Z,8E,10E)-N-(2-Hydroxy-2-methylpropyl)-2,6,8,10-dodecatetraenamide (CAS: 83883-10-7) typically synthesized?

Answer

(2E,6Z,8E,10E)-N-(2-Hydroxy-2-methylpropyl)-2,6,8,10-dodecatetraenamide
The compound (2E,6Z,8E,10E)-N-(2-Hydroxy-2-methylpropyl)-2,6,8,10-dodecatetraenamide (CAS: 83883-10-7) is synthesized via a multi-step process involving the reaction of a dodecatrienamide with a 2-hydroxy-2-methylpropylamine under basic conditions. The reaction is catalyzed by a mild base such as triethylamine, and the yield is around 70-75%. The purity is ensured through recrystallization and chromatographic purification.

About

CAS No 83883-10-7
English Name (2E,6Z,8E,10E)-N-(2-Hydroxy-2-methylpropyl)-2,6,8,10-dodecatetraenamide
Molecular Formula C16H25NO2
Molecular Weight 263.38 g/mol
SMILES C/C=C/C=C/C=C\CC/C=C/C(=O)NCC(C)(C)O
InChIKey LHFKHAVGGJJQFF-UEOYEZOQSA-N
Last Updated: 2025-09-29 09:43

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