N~2~-[(9H-Fluoren-9-ylmethoxy)carbonyl]-N~5~-{N-[(4-methylphenyl)sulfonyl]carbamimidoyl}-L-ornithine

Basic Information

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CAS Number

83792-47-6

Molecular Formula

C28H30N4O6S

Molecular Weight

550.64 g/mol

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Carboxylic Acids

Basic Chemical Raw Materials Organic Chemicals Ethers

Basic Chemical Raw Materials Organic Chemicals Amines

Fine Chemicals Dyes and Pigments Organic Dyes

Fine Chemicals Surfactants Anionic Surfactants

Basic Physical Properties

Physical State

No data available

Melting Point

92.0 to 96.0 deg-C

Boiling Point

No data available

Density

1.4±0.1 g/cm3

Refractive Index

1.656

SMILES

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CC1=CC=C(C=C1)S(=O)(=O)NC(=NCCCC(C(=O)O)NC(=O)OCC2C3=CC=CC=C3C4=CC=CC=C24)N

InChI

InChI=1S/C28H30N4O6S/c1-18-12-14-19(15-13-18)39(36,37)32-27(29)30-16-6-11-25(26(33)34)31-28(35)38-17-24-22-9-4-2-7-20(22)21-8-3-5-10-23(21)24/h2-5,7-10,12-15,24-25H,6,11,16-17H2,1H3,(H,31,35)(H,33,34)(H3,29,30,32)/t25-/m0/s1

InChIKey

JRRARHJPRLAGNT-VWLOTQADSA-N

LogP

3.569790000000003

Topological Polar Surface Area

157.68 Å²

Hydrogen Bond Donor/Acceptor

5 / 10

Complexity

953

Safety Information

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Hazard Statement

H302 Harmful if swallowed
Acute toxicity, oral

H315 Causes skin irritation
Skin corrosion/irritation

H319 Causes serious eye irritation
Serious eye damage/eye irritation

H335 May cause respiratory irritation
Specific target organ toxicity, single exposure; Respiratory tract irritation

Hazard Class

Class IRRITANT Class IRRITANT

Synonyms & References

English

F0883
PD196598
M03399
Fmoc-Arg(Tos)-OH
SCHEMBL119376
AS-14256
L-Ornithine, N2-[(9H-fluoren-9-ylmethoxy)carbonyl]-N5-[imino[[(4-methylphenyl)sulfonyl]amino]methyl]-
83792-47-6
(2S)-2-(9H-fluoren-9-ylmethoxycarbonylamino)-5-[[N-(p-tolylsulfonyl)carbamimidoyl]amino]pentanoic acid
(S)-2-(((9H-fluoren-9-yl)methoxy)carbonylamino)-5-(3-tosylguanidino)pentanoic acid
N-Alpha-Fmoc-N-g-tosyl-L-arginine
(2S)-2-{[(9H-fluoren-9-ylmethoxy)carbonyl]amino}-5-{3-[(4-methylbenzene)sulfonyl]carbamimidamido}pentanoic acid
MFCD00063331
AKOS015922867
BDBM9853
HY-W010745
Fmoc-Arg(Tos)-OH, >=95.0% (HPLC)
Nalpha-[(9H-Fluoren-9-ylmethoxy)carbonyl]-Nomega-tosyl-L-arginine
Nalpha-Fmoc-Nomega-tosyl-L-arginine
N2-(((9H-Fluoren-9-yl)methoxy)carbonyl)-Nw-tosyl-L-arginine
(2S)-5-[[amino-[(4-methylphenyl)sulfonylamino]methylidene]amino]-2-(9H-fluoren-9-ylmethoxycarbonylamino)pentanoic acid
CS-W011461
AKOS015895653
Arginine derivative 6
A840651
Nalpha-Fmoc-Nomega-(4-toluenesulfonyl)-L-arginine
N-alpha-(9-Fluorenylmethyloxycarbonyl)-N'-tosyl-L-arginine (Fmoc-L-Arg(Tos)-OH)
CHEMBL427133
N-Fmoc-N'-tosyl-L-arginine
N-(9-fluorenylmethoxycarbonyl)-N'-tosyl-L-arginine
Fmoc-Arg(Tos)-OH N-α-Fmoc-N-ω-tosyl-L-arginine

MDL Number

MFCD00063331

Customs Code

29350090

FAQ

What regulatory guidelines apply to N~2~-[(9H-Fluoren-9-ylmethoxy)carbonyl]-N~5~-{N-[(4-methylphenyl)sulfonyl]carbamimidoyl}-L-ornithine (CAS: 83792-47-6)?

This compound falls under various regulatory guidelines including REACH in Europe, and FDA/EPA regulations in the United States. It is classified under GHS as a hazardous chemical due to its reactivity and potential health effects. Compliance with local and international safety data sheets (SDS) and proper labeling is essential for handling and transportation.

Are there alternatives to N~2~-[(9H-Fluoren-9-ylmethoxy)carbonyl]-N~5~-{N-[(4-methylphenyl)sulfonyl]carbamimidoyl}-L-ornithine (CAS: 83792-47-6) in synthesis?

Common alternatives include other ornithine derivatives or simpler acyl ornithines. Isomers and analogs, such as N~2~-[(9H-fluoren-9-ylmethoxy)carbonyl]-L-ornithine or similar fluorenyl-protected ornithines, are also used. The choice of alternative depends on the specific reaction conditions and desired product characteristics.

What is the market or research trend for N~2~-[(9H-Fluoren-9-ylmethoxy)carbonyl]-N~5~-{N-[(4-methylphenyl)sulfonyl]carbamimidoyl}-L-ornithine (CAS: 83792-47-6)?

The market for this compound is primarily driven by its applications in pharmaceutical and biotechnological research. Recent trends show increased interest in fluorenyl-protected amino acids for drug discovery and enzyme inhibitors. Research is focusing on its potential in developing targeted therapies and personalized medicine.

How should waste containing N~2~-[(9H-Fluoren-9-ylmethoxy)carbonyl]-N~5~-{N-[(4-methylphenyl)sulfonyl]carbamimidoyl}-L-ornithine (CAS: 83792-47-6) be handled?

Waste containing this compound should be collected in appropriate containers and disposed of through professional waste disposal services. Incineration is a common method, but ensure it complies with local regulations. Environmental protection measures include proper ventilation and protective clothing for handlers. Always follow local and international hazardous waste disposal guidelines.