Cyclosporin H | CAS No. 83602-39-5

Cyclosporin H

Basic Information

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CAS Number

83602-39-5

Molecular Formula

C62H111N11O12

Molecular Weight

1202.61 g/mol

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Carboxylic Acids

Basic Chemical Raw Materials Organic Chemicals Heterocyclic Compounds

Pharmaceutical Chemicals Pharmaceutical Intermediates Heterocyclic Intermediates

Fine Chemicals Surfactants Anionic Surfactants

Polymers and Plastics Thermoplastics Polyolefins

Laboratory Chemicals Research Chemicals Biochemical Reagents

Basic Physical Properties

Melting Point

148-151°C

SMILES

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C/C=C/C[C@@H]([C@@H](C1C(=O)NCCCC(=O)N(C)CC(=O)N(C)[C@@H](CC(C)C)C(=O)N[C@@H](C(C)C)C(=O)N(C)[C@H](C(=O)N[C@H](C(=O)N[C@@H](C(=O)N([C@H](C(=O)N([C@H](C(=O)N([C@@H](C(=O)N1C)C(C)C)C)CC(C)C)C)CC(C)C)C)C)C)CC(C)C)O)C C62H111N11O12

InChI

InChI=1S/C62H111N11O12/c1-24-25-27-41(14)53(76)52-57(80)63-29-26-28-48(74)67(17)34-49(75)68(18)44(30-35(2)3)56(79)66-50(39(10)11)61(84)69(19)45(31-36(4)5)55(78)64-42(15)54(77)65-43(16)58(81)70(20)46(32-37(6)7)59(82)71(21)47(33-38(8)9)60(83)72(22)51(40(12)13)62(85)73(52)23/h24-25,35-47,50-53,76H,26-34H2,1-23H3,(H,63,80)(H,64,78)(H,65,77)(H,66,79)/b25-24+/t41-,42-,43+,44-,45-,46-,47-,50-,51+,52?,53-/m0/s1

InChIKey

WHHACJFHGITGOJ-BFLPRMFGSA-N

LogP

3.2706000000000026

Topological Polar Surface Area

278.8 Å²

Hydrogen Bond Donor/Acceptor

5 / 23

Complexity

2330

Synonyms & References

English

Cyclosporin H
Cyclo[L-alanyl-D-alanyl-N-methyl-L-leucyl-N-methyl-L-leucyl-N-methyl-D-valyl-3-hydroxy-N,4-dimethyl-L-2-amino-6-octenoyl-L-2-aminobutanoyl-N-methylglycyl-N-methyl-L-leucyl-L-valyl-N-methyl-L-leucyl]
Cyclosporin H, froM MicroMonospora
cyclosiversioside H
cyclosporin A
cyclosporine
Ciklosporin
Spectrum_000300
Spectrum4_001279
Spectrum3_001593
Spectrum2_001484
KBioSS_000780
KBioGR_001898
DivK1c_000871
SPBio_001467
KBio2_005916
KBio3_002686
KBio2_003348
KBio1_000871
KBio2_000780
NINDS_000871
HMS3267I20
HMS3372A06
HMS3654L18
HMS3651O16
30-Ethyl-33-(1-hydroxy-2-methylhex-4-enyl)-1,4,7,10,12,15,19,25,28-nonamethyl-6,9,18,24-tetrakis(2-m
Cyclosporine A
Cyclosporin
Antibiotic S 7481F1
Ciclosporin A
NSC290193

MDL Number

MFCD04039488

FAQ

What is Cyclosporin H (CAS: 83602-39-5)?

Cyclosporin H (CAS: 83602-39-5) is a cyclic peptide found in the extracts of the fungus Claviceps purpurea. It is characterized by its immunosuppressive properties and is widely used in the pharmaceutical industry, particularly in organ transplantation and autoimmune diseases.

What are the main uses of Cyclosporin H (CAS: 83602-39-5)?

Cyclosporin H (CAS: 83602-39-5) is primarily used as an immunosuppressant in organ transplants to prevent rejection. It also has applications in treating autoimmune diseases and is utilized in research for studying immune system function.

Is Cyclosporin H (CAS: 83602-39-5) safe?

Cyclosporin H (CAS: 83602-39-5) should be handled with caution as it can cause adverse effects such as nephrotoxicity, hypertension, and infections. Proper safety measures, including the use of personal protective equipment, should be followed to ensure safety.

How should Cyclosporin H (CAS: 83602-39-5) be stored?

Cyclosporin H (CAS: 83602-39-5) should be stored at a temperature below 20°C, in a cool, dry place, away from direct sunlight. It must be kept in a tightly sealed container to protect it from moisture and light exposure.