4-[4-({[4-Chloro-3-(trifluoromethyl)phenyl]carbamoyl}amino)-3-fluorophenoxy]-N-methyl-2-pyridinecarboxamide hydrochloride (1:1) | CAS No. 835621-07-3

4-[4-({[4-Chloro-3-(trifluoromethyl)phenyl]carbamoyl}amino)-3-fluorophenoxy]-N-methyl-2-pyridinecarboxamide hydrochloride (1:1)

Basic Information

CAS Number

835621-07-3

Molecular Formula

C21H16Cl2F4N4O3

Molecular Weight

519.28 g/mol

AD

Basic Physical Properties

CNC(=O)c1cc(ccn1)Oc2ccc(c(c2)F)NC(=O)Nc3ccc(c(c3)C(F)(F)F)Cl.Cl

InChI

InChI=1S/C21H15ClF4N4O3.ClH/c1-27-19(31)18-10-13(6-7-28-18)33-12-3-5-17(16(23)9-12)30-20(32)29-11-2-4-15(22)14(8-11)21(24,25)26;/h2-10H,1H3,(H,27,31)(H2,29,30,32);1H

InChIKey

ACSWJKPZXNIVMY-UHFFFAOYSA-N

LogP

6.1106000000000025

Topological Polar Surface Area

92.35 Ų

Hydrogen Bond Donor/Acceptor

3 / 7

Synonyms & References

English

  • Regorafenib (Hydrochloride)
  • BAY73-4506 hydrochloride
  • 4-[4-[[[[4-Chloro-3-(trifluoromethyl)phenyl]amino]carbonyl]amino]-3-fluorophenoxy]-N-methyl-2-pyridinecarboxamide hydrochloride
  • Regafenib HCL
  • Regafenib hydrochloride
  • 2-Pyridinecarboxamide,4-[4-[[[[4-chloro-3-(trifluoromethyl)phenyl]amino]carbonyl]amino]-3-fluorophenoxy]-N-methyl-, monohydrochloride
  • 4-[4-({[4-Chloro-3-(trifluoromethyl)phenyl]carbamoyl}amino)-3-fluorophenoxy]-N-methyl-2-pyridinecarboxamide hydrochloride (1:1)
  • 4-(4-(3-(4-Chloro-3-(trifluoromethyl)phenyl)ureido)-3-fluorophenoxy)-N-methylpicolinamide hydr
  • 2-Pyridinecarboxamide, 4-[4-[[[[4-chloro-3-(trifluoromethyl)phenyl]amino]carbonyl]amino]-3-fluoro phenoxy]-N-methyl-, monoh
  • 2-Pyridinecarboxamide, 4-[4-[[[[4-chloro-3-(trifluoromethyl)phenyl]amino]carbonyl]amino]-3-flu...
  • 4-[4-[[4-chloro-3-(trifluoromethyl)phenyl]carbamoylamino]-3-fluorophenoxy]-N-methylpyridine-2-carboxamide hydrochloride
  • Regorafenib Hydrochloride

MDL Number

MFCD22417053

FAQ

What is 4-[4-({[4-Chloro-3-(trifluoromethyl)phenyl]carbamoyl}amino)-3-fluorophenoxy]-N-methyl-2-pyridinecarboxamide hydrochloride (CAS: 835621-07-3)?

4-[4-({[4-Chloro-3-(trifluoromethyl)phenyl]carbamoyl}amino)-3-fluorophenoxy]-N-methyl-2-pyridinecarboxamide hydrochloride is a chemical compound with a complex structure. It is used primarily in pharmaceuticals and research for its biological activity.

What are the main uses of 4-[4-({[4-Chloro-3-(trifluoromethyl)phenyl]carbamoyl}amino)-3-fluorophenoxy]-N-methyl-2-pyridinecarboxamide hydrochloride (CAS: 835621-07-3)?

This compound is mainly used in the pharmaceutical industry for developing drugs with specific biological activities. It is also utilized in research for studying related molecular mechanisms and therapeutic potentials.

Is 4-[4-({[4-Chloro-3-(trifluoromethyl)phenyl]carbamoyl}amino)-3-fluorophenoxy]-N-methyl-2-pyridinecarboxamide hydrochloride (CAS: 835621-07-3) safe?

This compound is generally considered safe when handled with appropriate precautions. However, it should be used and stored under controlled conditions, and proper protective measures, such as gloves and goggles, should be taken to avoid skin and eye contact.

How should 4-[4-({[4-Chloro-3-(trifluoromethyl)phenyl]carbamoyl}amino)-3-fluorophenoxy]-N-methyl-2-pyridinecarboxamide hydrochloride (CAS: 835621-07-3) be stored?

This compound should be stored in a cool, dry place, away from direct sunlight and heat sources. It should be kept in a tightly sealed container to prevent degradation. Temperature should preferably be maintained below 25°C, and humidity should be controlled to minimize moisture exposure.

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