Ofloxacin | CAS No. 83380-47-6

Ofloxacin

Basic Information

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CAS Number

83380-47-6

Molecular Formula

C18H20FN3O4

Molecular Weight

361.4 g/mol

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Carboxylic Acids

Basic Chemical Raw Materials Organic Chemicals Ethers

Basic Chemical Raw Materials Organic Chemicals Heterocyclic Compounds

Pharmaceutical Chemicals Pharmaceutical Intermediates Heterocyclic Intermediates

Fine Chemicals Dyes and Pigments Organic Dyes

Fine Chemicals Surfactants Anionic Surfactants

Fine Chemicals Specialty Chemicals UV Stabilizers

Agricultural Chemicals Pesticides Herbicides

Basic Physical Properties

SMILES

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CC1COC2=C3N1C=C(C(=O)C3=CC(=C2N4CCN(CC4)C)F)C(=O)O

InChI

InChI=1S/C18H20FN3O4/c1-10-9-26-17-14-11(16(23)12(18(24)25)8-22(10)14)7-13(19)15(17)21-5-3-20(2)4-6-21/h7-8,10H,3-6,9H2,1-2H3,(H,24,25)

InChIKey

GSDSWSVVBLHKDQ-UHFFFAOYSA-N

LogP

log Kow = -0.39

Topological Polar Surface Area

75.01 Å²

Hydrogen Bond Donor/Acceptor

1 / 7

Complexity

634

Synonyms & References

English

Flobacin
KBioGR_000667
NSC 758178
MLS001074203
Prestwick3_000237
NCGC00015772-04
FLOXIN IN DEXTROSE 5% IN PLASTIC CONTAINER
AB00052263_14
UNII-A4P49JAZ9H
7H-Pyrido(1,2,3-de)-1,4-benzoxazine-6-carboxylic acid, 2,3-dihydro-9-fluoro-3-methyl-10-(4-methyl-1-piperazinyl)-7-oxo-, (+-)-
KBio3_002617
Olfoxacin Otic Soln
NC00466
NCGC00094219-06
BCP22048
HMS2235C05
AB00052263-13
Z56761309
SBI-0050879.P003
Ofloxacine; DL-8280; HOE-280
CHEMBL4
SDCCGSBI-0050879.P004
(+-)-9-Fluoro-2,3-dihydro-3-methyl-10-(4-methyl-1-piperazinyl)-7-oxo-7H-pyrido(1,2,3-de)-1,4-benzoxazine-6-carboxylic acid
SMR000058192
NCGC00261589-01
KBio2_001666
OFLOXACIN [MART.]
BRD-A24228527-001-19-0
NCGC00015772-13
(3R)-9-fluoro-3-methyl-10-(4-methylpiperazin-1-yl)-7-oxo-2,3-dihydro-7H-[1,4]oxazino[2,3,4-ij]quinoline-6-carboxylic acid
Tox21_500904

FAQ

What are the physical and chemical properties of Ofloxacin (CAS: 83380-47-6)?

Ofloxacin is an antibacterial agent with a molecular weight of approximately 415.42 g/mol. It has a crystalline form and a melting point of about 225°C. Ofloxacin is slightly soluble in water and has a low solubility in organic solvents. It is a weak acid and exhibits some reactivity with bases and reducing agents.

How is Ofloxacin (CAS: 83380-47-6) typically synthesized?

Ofloxacin is synthesized through a multi-step process involving the condensation of 4-quinolone and 6-fluoro-2-(piperidin-4-yl)-pyridine. Commonly used catalysts include acid or base catalysts. The synthesis involves coupling reactions and ring formation, yielding a high purity product with a yield of around 70-80%.

What industries use Ofloxacin (CAS: 83380-47-6)?

Ofloxacin is primarily used in the pharmaceutical industry for its antibacterial properties. It is also used in veterinary medicine to treat various bacterial infections in animals. While not a common application, it can be found in some personal care products and wound care treatments.

What precautions should be taken when handling Ofloxacin (CAS: 83380-47-6)?

When handling Ofloxacin, it is crucial to wear personal protective equipment (PPE) including gloves and safety glasses. Store it in a cool, dry place away from direct sunlight. In case of a spill, use appropriate cleaning agents and follow local safety guidelines. Refer to the Material Safety Data Sheet (MSDS) for detailed safety information and emergency procedures.