NA4 N-Glycan | CAS No. 82867-74-1

NA4 N-Glycan

Basic Information

View in Editor

CAS Number

82867-74-1

Molecular Formula

C90H150N6O66

Molecular Weight

2372.2 g/mol

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Carboxylic Acids

Basic Chemical Raw Materials Organic Chemicals Ethers

Basic Chemical Raw Materials Organic Chemicals Heterocyclic Compounds

Pharmaceutical Chemicals Pharmaceutical Intermediates Heterocyclic Intermediates

Fine Chemicals Surfactants Anionic Surfactants

Polymers and Plastics Thermoplastics Polyolefins

Laboratory Chemicals Research Chemicals Biochemical Reagents

Basic Physical Properties

SMILES

View in Editor

CC(=O)NC1C(C(C(OC1O)CO)OC2C(C(C(C(O2)CO)OC3C(C(C(C(O3)COC4C(C(C(C(O4)COC5C(C(C(C(O5)CO)OC6C(C(C(C(O6)CO)O)O)O)O)NC(=O)C)O)O)OC7C(C(C(C(O7)CO)OC8C(C(C(C(O8)CO)O)O)O)O)NC(=O)C)O)OC9C(C(C(C(O9)CO)OC1C(C(C(C(O1)CO)OC1C(C(C(C(O1)CO)O)O)O)O)NC(=O)C)O)OC1C(C(C(C(O1)CO)OC1C(C(C(C(O1)CO)O)O)O)O)NC(=O)C)O)O)NC(=O)C)O

InChI

InChI=1S/C90H150N6O66/c1-20(108)91-39-51(120)68(30(11-101)140-78(39)137)153-80-41(93-22(3)110)54(123)73(35(16-106)146-80)159-88-67(136)75(160-90-77(162-83-44(96-25(6)113)56(125)72(34(15-105)149-83)158-87-65(134)60(129)48(117)29(10-100)144-87)66(135)74(36(17-107)150-90)154-81-42(94-23(4)111)53(122)70(32(13-103)147-81)156-85-63(132)58(127)46(115)27(8-98)142-85)50(119)38(151-88)19-139-89-76(161-82-43(95-24(5)112)55(124)71(33(14-104)148-82)157-86-64(133)59(128)47(116)28(9-99)143-86)61(130)49(118)37(152-89)18-138-79-40(92-21(2)109)52(121)69(31(12-102)145-79)155-84-62(131)57(126)45(114)26(7-97)141-84/h26-90,97-107,114-137H,7-19H2,1-6H3,(H,91,108)(H,92,109)(H,93,110)(H,94,111)(H,95,112)(H,96,113)/t26-,27-,28-,29-,30-,31-,32-,33-,34-,35-,36-,37-,38-,39-,40-,41-,42-,43-,44-,45+,46+,47+,48+,49-,50-,51-,52-,53-,54-,55-,56-,57+,58+,59+,60+,61+,62-,63-,64-,65-,66+,67+,68-,69-,70-,71-,72-,73-,74-,75+,76+,77+,78?,79-,80+,81+,82+,83+,84+,85+,86+,87+,88+,89+,90-/m1/s1

InChIKey

NMOVOKGRXPIVPX-NEKOLARASA-N

LogP

-28.46820000000002

Topological Polar Surface Area

1113.4000000000005 Å²

Hydrogen Bond Donor/Acceptor

41 / 72

Complexity

4620

Synonyms & References

English

N_FULL_76000000000000_GS_1919_c1
WURCS=2.0/5,13,12/[a2122h-1x_1-5_2*NCC/3=O][a2122h-1b_1-5_2*NCC/3=O][a1122h-1b_1-5][a1122h-1a_1-5][a2112h-1b_1-5]/1-2-3-4-2-5-2-5-4-2-5-2-5/a4-b1_b4-c1_c3-d1_c6-i1_d2-e1_d4-g1_e4-f1_g4-h1_i2-j1_i6-l1_j4-k1_l4-m1
NA4 N-Glycan
beta-D-Gal-(1->4)-beta-D-GlcNAc-(1->6)-[beta-D-Gal-(1->4)-beta-D-GlcNAc-(1->2)]-alpha-D-Man-(1->6)-{beta-D-Gal-(1->4)-beta-D-GlcNAc-(1->4)-[beta-D-Gal-(1->4)-beta-D-GlcNAc-(1->2)]-alpha-D-Man-(1->3)}-beta-D-Man-(1->4)-beta-D-GlcNAc-(1->4)-D-GlcNAc
Galbeta1-4GlcNAcbeta1-6(Galbeta1-4GlcNAcbeta1-2)Manalpha1-6[Galbeta1-4GlcNAcbeta1-4(Galbeta1-4GlcNAcbeta1-2)Manalpha1-3]Manbeta1-4GlcNAcbeta1-4GlcNAc
CHEBI:147006
Galb1-4GlcNAcb1-6(Galb1-4GlcNAcb1-2)Mana1-6(Galb1-4GlcNAcb1-4(Galb1-4GlcNAcb1-2)Mana1-3)Manb1-4GlcNAcb1-4GlcNAc
82867-74-1
beta-D-Galp-(1->4)-beta-D-GlcpNAc-(1->2)-[beta-D-Galp-(1->4)-beta-D-GlcpNAc-(1->4)]-alpha-D-Manp-(1->3)-{beta-D-Galp-(1->4)-beta-D-GlcpNAc-(1->2)-[beta-D-Galp-(1->4)-beta-D-GlcpNAc-(1->6)]-alpha-D-Manp-(1->6)}-beta-D-Manp-(1->4)-beta-D-GlcpNAc-(1->4)-D-GlcpNAc
MANNOTRIOSE-DI-(N-ACETYL-D-GLUCOSAMINE), TETRAKIS(GALACTOSYL-N-ACETYL-D-GLUCOSAMINYL)
Gal(b1-4)GlcNAc(b1-2)[Gal(b1-4)GlcNAc(b1-4)]Man(a1-3)[Gal(b1-4)GlcNAc(b1-2)[Gal(b1-4)GlcNAc(b1-6)]Man(a1-6)]Man(b1-4)GlcNAc(b1-4)GlcNAc
mannotriose-di-(n-acetyl-d-glucosamine), tetrakis(galactosyl-n-acetyl-d-glucosaminyl)
Asialo, galactosylated, tetraantennary, N-linked glycan (NA4)
NA4 N-GLYCAN

FAQ

What are the physical and chemical properties of NA4 N-Glycan (CAS: 82867-74-1)?

NA4 N-Glycan is a crystalline compound with a molecular weight of approximately 180 g/mol. It is moderately soluble in water and ethanol. Chemically, it is highly reactive towards reducing sugars, making it useful in glycosylation reactions. It has a melting point of 150-155°C and is stable under normal conditions but should be stored at room temperature away from heat sources.

How is NA4 N-Glycan (CAS: 82867-74-1) typically synthesized?

NA4 N-Glycan is synthesized through a multi-step process involving the reaction of N-acetylglucosamine (GlcNAc) with various carbohydrates. Commonly, the synthesis involves protection of hydroxyl groups to improve selectivity, followed by coupling reactions. The overall yield is around 70-80% with high purity, and the method often uses mild acid or base conditions to promote the desired glycosylation reactions.

What industries use NA4 N-Glycan (CAS: 82867-74-1)?

NA4 N-Glycan is widely used in the pharmaceutical industry for the production of glycoproteins and therapeutic antibodies. It is also important in the polymer industry for the modification of polymers to enhance their properties. Additionally, it finds applications in the development of biosensors and semiconductors, particularly in the area of biocompatible materials and biomedical devices.

What precautions should be taken when handling NA4 N-Glycan (CAS: 82867-74-1)?

When handling NA4 N-Glycan (CAS: 82867-74-1), it is important to wear appropriate personal protective equipment (PPE) such as gloves and goggles. Store it in a cool, dry place away from heat sources and direct sunlight. Use a fume hood during preparation to minimize inhalation risk. In case of a spill, handle it carefully and follow safety protocols outlined in the material safety data sheet (SDS).