(R,Z)-Methyl 7-(3-((tert-butyldimethylsilyl)-oxy)-5-oxocyclopent-1-en-1-yl)hept-5-enoate | CAS No. 82542-42-5

(R,Z)-Methyl 7-(3-((tert-butyldimethylsilyl)-oxy)-5-oxocyclopent-1-en-1-yl)hept-5-enoate

Basic Information

CAS Number

82542-42-5

Molecular Formula

C19H32O4Si

Molecular Weight

352.55 g/mol

AD

Basic Physical Properties

Density

1.00±0.1 g/cm3 (20 ºC 760 Torr),

CC(C)(C)[Si](C)(C)OC1CC(=O)C(=C1)CC=CCCCC(=O)OC

InChI

InChI=1S/C19H32O4Si/c1-19(2,3)24(5,6)23-16-13-15(17(20)14-16)11-9-7-8-10-12-18(21)22-4/h7,9,13,16H,8,10-12,14H2,1-6H3/b9-7-/t16-/m0/s1

InChIKey

KMZNNYCERSPGGM-GQSKFBFOSA-N

LogP

4.565600000000004

Topological Polar Surface Area

52.6 Ų

Hydrogen Bond Donor/Acceptor

0 / 4

Complexity

512

Synonyms & References

English

  • (R,Z)-Methyl 7-(3-((tert-butyldimethylsilyl)-oxy)-5-oxocyclopent-1-en-1-yl)hept-5-enoate
  • 82542-42-5
  • (R,Z)-Methyl 7-(3-((tert-butyldimethylsilyl)oxy)-5-oxocyclopent-1-en-1-yl)hept-5-enoate
  • SCHEMBL4024707
  • (R,Z)-Methyl 7-(3-((Tert-Butyldimethylsilyl)Oxy)-5-Oxcyclopent-1-En-1-Yl)Hept-5-Enoate
  • (R,Z)-Methyl7-(3-((tert-butyldimethylsilyl)oxy)-5-oxocyclopent-1-en-1-yl)hept-5-enoate
  • J-517577
  • 5-Heptenoic acid,7-[(3R)-3-[[(1,1-dimethylethyl)dimethylsilyl]oxy]-5-oxo-1-cyclopenten-1-yl]-,methyl ester,(5Z)-
  • (R,Z)-Methyl 7-(3-((Tert-Butyldimethylsilyl)-Oxy)-5-Oxcyclopent-1-En-1-Yl)Hept-5-Enoate
  • methyl (Z)-7-[(3R)-3-[tert-butyl(dimethyl)silyl]oxy-5-oxocyclopenten-1-yl]hept-5-enoate
  • 5-Heptenoic acid, 7-[(3R)-3-[[(1,1-dimethylethyl)dimethylsilyl]oxy]-5-oxo-1-cyclopenten-1-yl ]-, methyl ester, (5Z)-

MDL Number

MFCD23135405

FAQ

What are the physical and chemical properties of (R,Z)-Methyl 7-(3-((tert-butyldimethylsilyl)-oxy)-5-oxocyclopent-1-en-1-yl)hept-5-enoate (CAS: 82542-42-5)?

This compound is a colorless solid with a molecular weight of approximately 416.49 g/mol. It has a low solubility in water but is soluble in organic solvents such as methanol and ethanol. It is known for its reactivity in various chemical transformations, particularly in organic synthesis.

How is (R,Z)-Methyl 7-(3-((tert-butyldimethylsilyl)-oxy)-5-oxocyclopent-1-en-1-yl)hept-5-enoate (CAS: 82542-42-5) typically synthesized?

This compound can be synthesized via a multi-step process involving alkylation, silylation, and ring-opening reactions. Commonly, a Michael addition followed by a silylation step using tert-butyldimethylsilyl chloride and imidazole is used. The reaction yields a high purity product with good selectivity.

What industries use (R,Z)-Methyl 7-(3-((tert-butyldimethylsilyl)-oxy)-5-oxocyclopent-1-en-1-yl)hept-5-enoate (CAS: 82542-42-5)?

This compound is primarily used in the pharmaceutical and chemical industries for intermediates in medicinal chemistry research. It can also be utilized in polymer chemistry and as a precursor in the synthesis of specialized organic compounds.

What precautions should be taken when handling (R,Z)-Methyl 7-(3-((tert-butyldimethylsilyl)-oxy)-5-oxocyclopent-1-en-1-yl)hept-5-enoate (CAS: 82542-42-5)?

Handling this compound requires appropriate personal protective equipment (PPE) such as gloves, goggles, and a lab coat. Work should be performed in a well-ventilated area, preferably with a fume hood. In case of a spill, contain the material using absorbent paper and dispose of according to local regulations. Always refer to the Safety Data Sheet (SDS) for detailed safety information.

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