4-(2-Methyl-2-propanyl)-L-phenylalanine

Basic Information

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CAS Number

82372-74-5

Molecular Formula

C13H19NO2

Molecular Weight

221.3 g/mol

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Carboxylic Acids

Basic Chemical Raw Materials Organic Chemicals Amines

Fine Chemicals Dyes and Pigments Organic Dyes

Fine Chemicals Surfactants Anionic Surfactants

Basic Physical Properties

Density

1.084±0.06 g/cm3 (20 ºC 760 Torr),

SMILES

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CC(C)(C)c1ccc(C[C@H](N)C(=O)O)cc1

InChI

InChI=1S/C13H19NO2/c1-13(2,3)10-6-4-9(5-7-10)8-11(14)12(15)16/h4-7,11H,8,14H2,1-3H3,(H,15,16)/t11-/m0/s1

InChIKey

CSJZKSXYLTYFPU-NSHDSACASA-N

LogP

1.9385000000000001

Topological Polar Surface Area

63.32000000000001 Å²

Hydrogen Bond Donor/Acceptor

3 / 3

Complexity

237

Synonyms & References

English

(S)-2-Amino-3-(4-(tert-butyl)phenyl)propanoic acid
H-Phe(4-tBu)-OH
4-tert-Butyl-L-phenylalanine
L-4-tBu-Phe-OH
L-4-tButylphenylalanine
L-4-tert-Butyl-Phe
L-4-TERT-BUTYL-PHENYLALANINE
L-Phenylalanine,4-(1,1-dimethylethyl)-
(2S)-2-amino-3-(4-tert-butylphenyl)propanoic acid
10YZ0R5GQ0
4-(1,1-dimethylethyl)-L-phenylalanine
D-4-tert-Butyl-phenylalanine
(2S)-2-amino-3-(4-tert-butylphenyl)propionic acid
(2S)-2-azanyl-3-(4-tert-butylphenyl)propanoic acid
AK117430
L-(4-tBu)Phe-OH
p-tert-Butylphenylalanine
L-Phenylalanine, 4-(1,1-dimethylet

MDL Number

MFCD02259528

Customs Code

2922499990

FAQ

What are the physical and chemical properties of 4-(2-Methyl-2-propanyl)-L-phenylalanine (CAS: 82372-74-5)?

4-(2-Methyl-2-propanyl)-L-phenylalanine is a white crystalline solid with a molecular weight of approximately 264.34 g/mol. It has a high solubility in water and organic solvents. This compound is moderately reactive, showing some amphoteric behavior. It decomposes above 200°C. It is a chiral molecule with optical activity.

How is 4-(2-Methyl-2-propanyl)-L-phenylalanine (CAS: 82372-74-5) typically synthesized?

4-(2-Methyl-2-propanyl)-L-phenylalanine is synthesized via a multi-step process, often involving the protection of the carboxylic acid, followed by alkylation and deprotection. Commonly used catalysts include acids such as trifluoroacetic acid, and the reaction is typically carried out under anhydrous conditions. The yield is usually in the range of 70-85%, with high selectivity to the desired product.

What industries use 4-(2-Methyl-2-propanyl)-L-phenylalanine (CAS: 82372-74-5)?

4-(2-Methyl-2-propanyl)-L-phenylalanine is primarily used in the pharmaceutical industry for the synthesis of drugs and intermediates. It also finds applications in the polymer industry as a monomer, and in the field of sensors and semiconductors as a precursor for functional materials.

What precautions should be taken when handling 4-(2-Methyl-2-propanyl)-L-phenylalanine (CAS: 82372-74-5)?

When handling 4-(2-Methyl-2-propanyl)-L-phenylalanine, it is important to wear appropriate personal protective equipment (PPE), including gloves, goggles, and a lab coat. Store the compound in a cool, dry place, away from heat sources and incompatible materials. Spills should be cleaned up using appropriate absorbent materials, and the area should be ventilated. Always refer to the Safety Data Sheet (SDS) for specific handling instructions and emergency procedures.