Atomoxetine HCl

Basic Information

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CAS Number

82248-59-7

Molecular Formula

C17H22ClNO

Molecular Weight

291.82 g/mol

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Ethers

Agricultural Chemicals Pesticides Herbicides

Basic Physical Properties

Melting Point

167.0 to 171.0 deg-C

Boiling Point

389°C at 760 mmHg

Flash Point

9℃

Specific Rotation

D25 -38.01°; 36525 -177.26° (c = 1 in methanol); D23 -41.37° (c = 1.02 in methanol); D25 -40.3° (c = 0.94 in ethanol)

SMILES

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Cl.CNCC[C@@H](Oc1ccccc1C)c2ccccc2

InChI

InChI=1S/C17H21NO.ClH/c1-14-8-6-7-11-16(14)19-17(12-13-18-2)15-9-4-3-5-10-15;/h3-11,17-18H,12-13H2,1-2H3;1H/t17-;/m1./s1

InChIKey

LUCXVPAZUDVVBT-UNTBIKODSA-N

LogP

4.1464200000000035

pKa

10.13(at 25℃)

Topological Polar Surface Area

21.259999999999998 Å²

Hydrogen Bond Donor/Acceptor

1 / 2

Complexity

237

Safety Information

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Hazard Statement

H315 Causes skin irritation
Skin corrosion/irritation

H319 Causes serious eye irritation
Serious eye damage/eye irritation

H335 May cause respiratory irritation
Specific target organ toxicity, single exposure; Respiratory tract irritation

Synonyms & References

English

(R)-N-Methyl-3-phenyl-3-(o-tolyloxy)propan-1-amine hydrochloride
Atomoxetine HCl
(R)-N-Methyl-3-phenyl-3-(o-tolyloxy)-propan-1-amine hydrochloride
Atomoxetine hydrochloride solution
ATOMOXITINE
Tomoxetine hydrochloride
(3R)-N-methyl-3-(2-methylphenoxy)-3-phenylpropan-1-amine Hydrochloride
(R)-N-Methyl-(2-methylphenoxy)benzenepropanamine Hydrochloride
LY 139603
R-Tomexetine Hydrochloride
Strattera
(R)-N-Methyl-γ-(2-methylphenoxy)benzenepropanamine hydrochloride
Atomoxetine hydrochloride
(R)-N-Methyl-3-(2-methylphenoxy)-3-phenylpropylamine Hydrochloride
(R)-Tomoxetine Hydrochloride
(R)-N-Methyl-gamma-(2-methyl-phenoxy)benzenepropanamine hydrochloride
(R)-Tomoxetine hydrochloride
(R)-Atomoxetine hydrochloride
(R)-N-methyl-3-phenyl-3-(o-tolyloxy)propan-1-amine
hydrochloride (1:1)

MDL Number

MFCD06410992

Customs Code

2922299090

FAQ

What is Atomoxetine HCl (CAS: 82248-59-7)?

Atomoxetine HCl is a selective norepinephrine reuptake inhibitor (SNRI) used primarily in the treatment of attention deficit hyperactivity disorder (ADHD). Its chemical formula is C10H15NO2·HCl, and it is a white to off-white crystalline powder with good solubility in water. It is commonly prescribed as a medication due to its efficacy in managing ADHD symptoms and its relatively favorable side effect profile compared to other stimulant medications.

What are the main uses of Atomoxetine HCl (CAS: 82248-59-7)?

The primary use of Atomoxetine HCl is as a medication for attention deficit hyperactivity disorder (ADHD). It is also used in the treatment of depression and other mood disorders. In pharmaceutical applications, it serves as an active ingredient in various formulations, and in research, it is utilized to study the effects of norepinephrine modulation on cognitive and behavioral functions.

Is Atomoxetine HCl (CAS: 82248-59-7) safe?

Atomoxetine HCl is generally considered safe when used as directed. However, like all medications, it may cause side effects such as nausea, insomnia, and decreased appetite. It is important to follow prescribed dosages and consult healthcare professionals. Safety standards are established by regulatory bodies, and proper handling is necessary to prevent contamination or exposure risks.

How should Atomoxetine HCl (CAS: 82248-59-7) be stored?

Atomoxetine HCl should be stored in a cool, dry place away from direct light. The recommended storage temperature is between 15°C and 30°C (59°F and 86°F). It should be kept in a sealed container to maintain stability and prevent moisture absorption. Proper storage conditions ensure the medication remains effective and safe for use over time.