2-Amino-4-iodopyrimidine

Basic Information

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CAS Number

815610-16-3

Molecular Formula

C4H4IN3

Molecular Weight

221 g/mol

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Amines

Basic Chemical Raw Materials Organic Chemicals Heterocyclic Compounds

Pharmaceutical Chemicals Pharmaceutical Intermediates Heterocyclic Intermediates

Agricultural Chemicals Pesticides Herbicides

Basic Physical Properties

Boiling Point

364.9℃ at 760 mmHg

Density

2.204±0.06 g/cm3 (20 ºC 760 Torr),

SMILES

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C1=CN=C(N=C1I)N

InChI

InChI=1S/C4H4IN3/c5-3-1-2-7-4(6)8-3/h1-2H,(H2,6,7,8)

InChIKey

YTFBUSIUBSVISR-UHFFFAOYSA-N

LogP

0.6634

Topological Polar Surface Area

51.8 Å²

Hydrogen Bond Donor/Acceptor

2 / 3

Complexity

77.7

Synonyms & References

English

2-Amino-4-iodopyrimidine
4-iodopyrimidin-2-amine
815610-16-3
AS-30869
CS-0054051
YTFBUSIUBSVISR-UHFFFAOYSA-N
4-iodopyrimidine-2-amine
4-IODOPYRIMIDIN-2-AMINE
SB11834
AC-30166
SCHEMBL2665348
MFCD12406140
EN300-117565
DTXSID40671995
AKOS015999209
SY056892
2-Pyrimidinamine, 4-iodo-

MDL Number

MFCD12406140

FAQ

What are the physical and chemical properties of 2-Amino-4-iodopyrimidine (CAS: 815610-16-3)?

2-Amino-4-iodopyrimidine (CAS: 815610-16-3) is a crystalline solid with a molecular weight of approximately 236.03 g/mol. It has a low solubility in water but is more soluble in organic solvents such as ethanol and dimethylformamide. The compound is relatively stable but can undergo hydrolysis under acidic or basic conditions. It is generally unreactive towards common nucleophiles but can participate in nucleophilic substitution reactions under specific conditions.

How is 2-Amino-4-iodopyrimidine (CAS: 815610-16-3) typically synthesized?

2-Amino-4-iodopyrimidine (CAS: 815610-16-3) is typically synthesized via the nucleophilic substitution of 4-iodopyrimidine with ammonia in the presence of a base such as sodium hydroxide. The reaction proceeds to give a high yield of the desired product with good selectivity. This method involves the use of a gentle heating process under anhydrous conditions to ensure the reaction goes to completion.

What industries use 2-Amino-4-iodopyrimidine (CAS: 815610-16-3)?

2-Amino-4-iodopyrimidine (CAS: 815610-16-3) is used in the pharmaceutical industry as a precursor for the synthesis of certain drugs. It is also utilized in the polymer industry for the development of advanced materials with specific properties. Additionally, this compound finds applications in the semiconductor industry for the fabrication of electronic materials and in sensor technology for its unique chemical reactivity.

What precautions should be taken when handling 2-Amino-4-iodopyrimidine (CAS: 815610-16-3)?

When handling 2-Amino-4-iodopyrimidine (CAS: 815610-16-3), it is important to wear appropriate personal protective equipment (PPE) such as gloves, goggles, and a laboratory coat. The substance should be handled in a well-ventilated area or under a fume hood to minimize exposure to vapors. In case of spill, the area should be cleaned up immediately using appropriate absorbents. It is crucial to refer to the Safety Data Sheet (SDS) for specific handling and emergency procedures.