N-[(9H-Fluoren-9-ylmethoxy)carbonyl]-1-{[(2-methyl-2-propanyl)oxy]carbonyl}-L-histidine | CAS No. 81379-52-4

N-[(9H-Fluoren-9-ylmethoxy)carbonyl]-1-{[(2-methyl-2-propanyl)oxy]carbonyl}-L-histidine

Basic Information

CAS Number

81379-52-4

Molecular Formula

C26H27N3O6

Molecular Weight

477.52 g/mol

AD

Basic Physical Properties

Density

1.32

CC(C)(C)OC(=O)N1C=C(N=C1)CC(C(=O)O)NC(=O)OCC2C3=CC=CC=C3C4=CC=CC=C24

InChI

InChI=1S/C26H27N3O6/c1-26(2,3)35-25(33)29-13-16(27-15-29)12-22(23(30)31)28-24(32)34-14-21-19-10-6-4-8-17(19)18-9-5-7-11-20(18)21/h4-11,13,15,21-22H,12,14H2,1-3H3,(H,28,32)(H,30,31)/t22-/m0/s1

InChIKey

ZRHPMMZWDWMKPD-QFIPXVFZSA-N

LogP

4.200700000000003

Topological Polar Surface Area

119.75 Ų

Hydrogen Bond Donor/Acceptor

2 / 9

Complexity

762

Synonyms & References

English

  • Na-(((9H-Fluoren-9-yl)methoxy)carbonyl)-Nt-(tert-butoxycarbonyl)-L-histidine
  • (S)-2-(((9H-fluoren-9-yl)methoxy)carbonylamino)-3-(1-(tert-butoxycarbonyl)-1H-imidazol-4-yl)propanoic acid
  • fmoc-his(1-boc)-oh
  • CS-0067108
  • MFCD00151928
  • AKOS015907010
  • Fmoc-His(Boc)-OH?DCHA
  • FD21684
  • 1-Boc-Nalpha-Fmoc-L-histidine
  • HY-W025807
  • N-alpha-(9-Fluorenylmethyloxycarbonyl)-Nim-(t-butyloxycarbonyl)-L-histidine
  • 1-[(1,1-Dimethylethoxy)carbonyl]-N-[(9H-fluoren-9-ylmethoxy)carbonyl]-L-histidine
  • (2S)-2-(9H-fluoren-9-ylmethoxycarbonylamino)-3-[1-[(2-methylpropan-2-yl)oxycarbonyl]imidazol-4-yl]propanoic acid
  • 81379-52-4
  • AC-1897
  • PD197072
  • N-Fmoc-N'-Boc-L-histidine
  • Fmoc-His(Boc)-OH
  • SCHEMBL3439705
  • Fmoc-L-His(Boc)-OH
  • AS-49158
  • Fmoc-His(1-Boc)-OH
  • Fmoc-His(Boc)-OH.CHA
  • Fmoc-His(Boc)-OH·CHA
  • Nα-Fmoc-Nim-Boc-L-histidine cyclohexylammonium salt
  • Fmoc-His(Boc)
  • Fmoc-L-His(Boc)
  • HO-His(Boc)-Fmoc
  • Nα-(Fluoren-9-ylmethoxycarbonyl)-N(im)-(tert-butyloxycarbonyl)-L-histidine

MDL Number

MFCD00151928

FAQ

What is N-[(9H-Fluoren-9-ylmethoxy)carbonyl]-1-{[(2-methyl-2-propanyl)oxy]carbonyl}-L-histidine (CAS: 81379-52-4)?

N-[(9H-Fluoren-9-ylmethoxy)carbonyl]-1-{[(2-methyl-2-propanyl)oxy]carbonyl}-L-histidine is a complex organic compound used in the pharmaceutical industry for preparing prodrugs and in research for protein synthesis and structural studies. It contains a fluorenylmethoxycarbonyl group and a propanol group attached to a histidine residue.

What are the main uses of N-[(9H-Fluoren-9-ylmethoxy)carbonyl]-1-{[(2-methyl-2-propanyl)oxy]carbonyl}-L-histidine (CAS: 81379-52-4)?

N-[(9H-Fluoren-9-ylmethoxy)carbonyl]-1-{[(2-methyl-2-propanyl)oxy]carbonyl}-L-histidine is primarily used in drug development as a prodrug building block and in academic research for peptide and protein synthesis. It is also utilized in the synthesis of pharmaceutical intermediates.

Is N-[(9H-Fluoren-9-ylmethoxy)carbonyl]-1-{[(2-methyl-2-propanyl)oxy]carbonyl}-L-histidine (CAS: 81379-52-4) safe?

N-[(9H-Fluoren-9-ylmethoxy)carbonyl]-1-{[(2-methyl-2-propanyl)oxy]carbonyl}-L-histidine is generally safe when handled with appropriate caution. Users should follow standard laboratory safety protocols, wear personal protective equipment, and ensure proper ventilation. Storage should be in a cool, dry place away from direct sunlight and heat sources.

How should N-[(9H-Fluoren-9-ylmethoxy)carbonyl]-1-{[(2-methyl-2-propanyl)oxy]carbonyl}-L-histidine (CAS: 81379-52-4) be stored?

N-[(9H-Fluoren-9-ylmethoxy)carbonyl]-1-{[(2-methyl-2-propanyl)oxy]carbonyl}-L-histidine should be stored in a cool, dry place between 15°C and 25°C, protected from light and moisture. Use a sealed container to prevent degradation. Avoid exposure to high temperatures and direct sunlight to maintain its stability and efficacy.

Related Compounds

You might also like

Compound Q&A

What is 6-Methyl-7-oxabicyclo[4.1.0]heptan-2-one (CAS: 21889-89-4)?

6-Methyl-7-oxabicyclo[4.1.0]heptan-2-one is a cyclic ketone with a molecular for...

21889-89-46-Methyl-7-oxabicycl...
Compound Q&A

What is 4-[(6-Methyl-2-pyrazinyl)oxy]benzoic acid (CAS: 906353-00-2)?

4-[(6-Methyl-2-pyrazinyl)oxy]benzoic acid is a chemical compound with the CAS nu...

906353-00-24-[(6-Methyl-2-pyraz...
Compound Q&A

What is 2-(2-Pyridinyl)-1,3-propanediol (CAS: 49745-42-8)?

2-(2-Pyridinyl)-1,3-propanediol (CAS: 49745-42-8) is a colorless to slightly yel...

49745-42-82-(2-Pyridinyl)-1,3-...
Compound Q&A

What is 2-(6-Chloro-2-pyridinyl)-2-phenylacetonitrile (CAS: 24783-42-4)?

2-(6-Chloro-2-pyridinyl)-2-phenylacetonitrile is an organic compound with the CA...

24783-42-42-(6-Chloro-2-pyridi...
Compound Q&A

What is 2-Oxopropanamide (CAS: 631-66-3)?

2-Oxopropanamide, also known as 2-aminoacrylic acid, is a chemical compound with...

631-66-32-Oxopropanamide
Compound Q&A

What is 2-Methyl-2-propanyl 4-(5-bromo-6-methyl-2-pyridinyl)-1-piperazinecarboxylate (CAS: 1289040-88-5)?

2-Methyl-2-propanyl 4-(5-bromo-6-methyl-2-pyridinyl)-1-piperazinecarboxylate (CA...

1289040-88-52-Methyl-2-propanyl ...
Compound Q&A

What is NAMPT inhibitor-linker 1 (CAS: 2241019-57-6)?

NAMPT inhibitor-linker 1 (CAS: 2241019-57-6) is a chemical compound designed as ...

2241019-57-6NAMPT inhibitor-link...
Compound Q&A

What is (2-(2,2,2-Trifluoroacetyl)pyridin-4-yl)boronic acid (CAS: 1310404-58-0)?

It is a chemical compound with the structure (2-(2,2,2-Trifluoroacetyl)pyridin-4...

1310404-58-0(2-(2,2,2-Trifluoroa...
Compound Q&A

What is 1-(2-Chlorophenyl)-6-(3,3,3-trifluoro-2-methylpropyl)-1,5-dihydro-4H-pyrazolo[3,4-d]pyrimidin-4-one (CAS: 794568-90-4)?

1-(2-Chlorophenyl)-6-(3,3,3-trifluoro-2-methylpropyl)-1,5-dihydro-4H-pyrazolo[3,...

794568-90-41-(2-Chlorophenyl)-6...
Compound Q&A

What is Vinyl(chloromethyl)dimethoxysilane (CAS: 1314981-48-0)?

Vinyl(chloromethyl)dimethoxysilane is an organosilicon compound with the molecul...

1314981-48-0Vinyl(chloromethyl)d...