5'-O-[Bis(4-methoxyphenyl)(phenyl)methyl]uridine | CAS No. 81246-79-9

5'-O-[Bis(4-methoxyphenyl)(phenyl)methyl]uridine

Basic Information

CAS Number

81246-79-9

Molecular Formula

C30H30N2O8

Molecular Weight

546.58 g/mol

AD

Basic Physical Properties

COC1=CC=C(C=C1)C(C2=CC=CC=C2)(C3=CC=C(C=C3)OC)OCC4C(C(C(O4)N5C=CC(=O)NC5=O)O)O

InChI

InChI=1S/C30H30N2O8/c1-37-22-12-8-20(9-13-22)30(19-6-4-3-5-7-19,21-10-14-23(38-2)15-11-21)39-18-24-26(34)27(35)28(40-24)32-17-16-25(33)31-29(32)36/h3-17,24,26-28,34-35H,18H2,1-2H3,(H,31,33,36)/t24-,26-,27-,28-/m1/s1

InChIKey

PCFSNQYXXACUHM-YULOIDQLSA-N

LogP

2.1816999999999993

Topological Polar Surface Area

132.24 Ų

Hydrogen Bond Donor/Acceptor

3 / 10

Complexity

868

Synonyms & References

English

  • 5'-O-[bis(4-methoxyphenyl)phenylmethyl]uridine
  • 81246-79-9
  • J-700364
  • MFCD00057909
  • BS-32827
  • 5'-O-DMT-rU
  • 1-[(2R,3R,4S,5R)-5-{[bis(4-methoxyphenyl)(phenyl)methoxy]methyl}-3,4-dihydroxyoxolan-2-yl]-1,2,3,4-tetrahydropyrimidine-2,4-dione
  • 5'-O-(4,4'-Dimethoxytrityl)uridine
  • 5'-O-DMT-uridine
  • SCHEMBL918582
  • CHEMBL3798292
  • DTXSID301250023
  • 5 inverted exclamation mark -DMT-rU
  • 5'-O-(Dimethoxytrityl)-uridine
  • E72623
  • 1-[(2R,3R,4S,5R)-5-[[bis(4-methoxyphenyl)-phenylmethoxy]methyl]-3,4-dihydroxyoxolan-2-yl]pyrimidine-2,4-dione
  • PD157773
  • AC-32226
  • 1-((2R,3R,4S,5R)-5-((bis(4-methoxyphenyl)(phenyl)methoxy)methyl)-3,4-dihydroxytetrahydrofuran-2-yl)pyrimidine-2,4(1H,3H)-dione
  • AKOS024463756
  • PCFSNQYXXACUHM-YULOIDQLSA-N
  • HY-138609
  • 5'-O-(4,4'-dimethoxytrityl) uridine
  • CS-0159302
  • 5’-DMT-rU
  • Uridine, 5'-O-[bis(4-methoxyphenyl)phenylmethyl]-
  • Uridine, 5'-O-[α,α-bis(p-methoxyphenyl)benzyl]- (7CI)
  • 5'-DMT-rU
  • 5'-DMTr-uridine
  • 5'-O-DMTr-uridine
  • DMT-RIBOURIDINE

MDL Number

MFCD00057909

FAQ

What are the physical and chemical properties of 5'-O-[Bis(4-methoxyphenyl)(phenyl)methyl]uridine (CAS: 81246-79-9)?

5'-O-[Bis(4-methoxyphenyl)(phenyl)methyl]uridine is a white crystalline solid with a molecular weight of approximately 510.4 g/mol. It is poorly soluble in water but soluble in organic solvents like DMSO and DMF. The compound exhibits low reactivity under normal conditions but can undergo base-catalyzed hydrolysis. It is stable under acidic and neutral conditions.

How is 5'-O-[Bis(4-methoxyphenyl)(phenyl)methyl]uridine (CAS: 81246-79-9) typically synthesized?

5'-O-[Bis(4-methoxyphenyl)(phenyl)methyl]uridine is synthesized via a multi-step process involving the protection of uridine, followed by the introduction of the bis(4-methoxyphenyl)(phenyl)methyl group. Common synthetic routes use coupling agents like HATU, and the reaction is typically carried out in anhydrous conditions to maximize yield. The exact method can vary slightly depending on the conditions chosen.

What industries use 5'-O-[Bis(4-methoxyphenyl)(phenyl)methyl]uridine (CAS: 81246-79-9)?

5'-O-[Bis(4-methoxyphenyl)(phenyl)methyl]uridine is primarily used in pharmaceutical research for its unique chemical properties. It is also utilized in the development of novel sensor technologies and in the synthesis of certain polymers and organic materials due to its structural complexity and reactivity.

What precautions should be taken when handling 5'-O-[Bis(4-methoxyphenyl)(phenyl)methyl]uridine (CAS: 81246-79-9)?

When handling 5'-O-[Bis(4-methoxyphenyl)(phenyl)methyl]uridine, it is crucial to wear appropriate personal protective equipment (PPE), including gloves and safety goggles. The compound should be stored in a cool, dry place away from direct sunlight. In case of a spill, it should be cleaned up under a fume hood using appropriate absorbent materials. Always refer to the material safety data sheet (MSDS) for detailed handling and disposal instructions.

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