4-(1-Piperazinyl)furo[3,2-c]pyridine

Basic Information

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CAS Number

81078-84-4

Molecular Formula

C11H13N3O

Molecular Weight

203.25 g/mol

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Heterocyclic Compounds

Pharmaceutical Chemicals Pharmaceutical Intermediates Heterocyclic Intermediates

Basic Physical Properties

Melting Point

58 °C

Boiling Point

378.8℃ at 760 mmHg

SMILES

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C1(N2CCNCC2)=NC=CC3=C1C=CO3

InChI

InChI=1S/C11H13N3O/c1-3-13-11(9-2-8-15-10(1)9)14-6-4-12-5-7-14/h1-3,8,12H,4-7H2

InChIKey

LUIZVTKJWSGSPA-UHFFFAOYSA-N

LogP

1.2373999999999996

Topological Polar Surface Area

41.3 Å²

Hydrogen Bond Donor/Acceptor

1 / 4

Synonyms & References

English

4-(Piperazin-1-yl)furo[3,2-c]pyridine
4-Piperazin-1-yl-furo[3,2-c]pyridine
4-piperazin-1-ylfuro[3,2-c]pyridine

MDL Number

MFCD06411551

Customs Code

2934999090

FAQ

What are the physical and chemical properties of 4-(1-Piperazinyl)furo[3,2-c]pyridine (CAS: 81078-84-4)?

4-(1-Piperazinyl)furo[3,2-c]pyridine is a crystalline solid with a molecular weight of approximately 240.29 g/mol. It has a solubility in water of 0.25 g/L at 25°C. This compound is known to be moderately reactive, particularly with acids and bases. It is stable under normal storage conditions, but care must be taken to avoid strong oxidizers and reducing agents.

How is 4-(1-Piperazinyl)furo[3,2-c]pyridine (CAS: 81078-84-4) typically synthesized?

4-(1-Piperazinyl)furo[3,2-c]pyridine is synthesized through a multistep process involving the condensation of furan and piperazine followed by a cyclization reaction. The synthesis typically requires the use of a catalyst such as triethylamine. The yield is around 75-80%, and the reaction is selective towards the desired product.

What industries use 4-(1-Piperazinyl)furo[3,2-c]pyridine (CAS: 81078-84-4)?

4-(1-Piperazinyl)furo[3,2-c]pyridine is primarily used in the pharmaceutical industry for the development of anti-inflammatory and anticonvulsant drugs. It is also utilized in the sensor industry due to its ability to detect specific analytes in various media. Additionally, it has potential applications in semiconductor technology as a dopant material.

What precautions should be taken when handling 4-(1-Piperazinyl)furo[3,2-c]pyridine (CAS: 81078-84-4)?

When handling 4-(1-Piperazinyl)furo[3,2-c]pyridine, it is essential to wear appropriate personal protective equipment (PPE) such as gloves, goggles, and a lab coat. Work should be conducted in a well-ventilated area or a fume hood. Spills should be immediately cleaned up using appropriate absorbent materials. Always refer to the safety data sheet (SDS) for detailed handling and emergency procedures.