Concanamycin A

Basic Information

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CAS Number

80890-47-7

Molecular Formula

C46H75NO14

Molecular Weight

866.09 g/mol

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Carboxylic Acids

Basic Chemical Raw Materials Organic Chemicals Esters

Basic Chemical Raw Materials Organic Chemicals Ethers

Basic Chemical Raw Materials Organic Chemicals Amines

Basic Chemical Raw Materials Organic Chemicals Heterocyclic Compounds

Pharmaceutical Chemicals Pharmaceutical Intermediates Heterocyclic Intermediates

Fine Chemicals Surfactants Anionic Surfactants

Polymers and Plastics Thermoplastics Polyolefins

Laboratory Chemicals Research Chemicals Biochemical Reagents

Basic Physical Properties

Melting Point

179-180 ºC (dichloromethane ethanol )

Boiling Point

966.4±65.0 °C at 760 mmHg

Density

1.20±0.1 g/cm3 (20 ºC 760 Torr),

Flash Point

538.3±34.3 °C

SMILES

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C/C=C/[C@H]1O[C@](O)(C[C@H]([C@@H]1C)O[C@H]1C[C@@H](O)[C@@H]([C@H](O1)C)OC(=O)N)[C@H]([C@@H]([C@@H]([C@H]1OC(=O)/C(=C/C(=C/[C@@H](C)[C@@H](O)[C@H]([C@H]([C@@H](C/C(=C/C=C/[C@@H]1OC)/C)C)O)CC)/C)/OC)C)O)C

InChI

InChI=1S/C46H75NO14/c1-13-16-34-28(7)37(58-38-22-33(48)43(31(10)57-38)60-45(47)53)23-46(54,61-34)30(9)41(51)29(8)42-35(55-11)18-15-17-24(3)19-26(5)39(49)32(14-2)40(50)27(6)20-25(4)21-36(56-12)44(52)59-42/h13,15-18,20-21,26-35,37-43,48-51,54H,14,19,22-23H2,1-12H3,(H2,47,53)/b16-13+,18-15+,24-17+,25-20+,36-21-/t26-,27-,28-,29+,30+,31-,32+,33-,34-,35+,37-,38+,39+,40-,41-,42-,43-,46-/m1/s1

InChIKey

DJZCTUVALDDONK-HQMSUKCRSA-N

LogP

4.9839000000000055

Topological Polar Surface Area

225.91999999999996 Å²

Hydrogen Bond Donor/Acceptor

7 / 15

Complexity

1580

Safety Information

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GHS Hazard Pictograms

H300

H310

H319

H330

Hazard Statement

H300 Fatal if swallowed
Acute toxicity, oral

H310 Fatal in contact with skin
Acute toxicity, dermal

H319 Causes serious eye irritation
Serious eye damage/eye irritation

H330 Fatal if inhaled
Acute toxicity, inhalation

Hazard Class

Class 6.1(b) Class 6.1(b)

Sensitiveness

对湿度敏感

Synonyms & References

English

CONCANAMYCIN A
antibioticx4357b
x4357b
FOLIMYCIN
FOLIMYCIN, STREPTOMYCES SP
FOLIMYCIN, STREPTOMYCES SPECIES
CONCANAMYCIN A, STREPTOMYCES SP
concanamycin A from streptomyces species
Cocanamycin A
Concanamycin A,(3Z,5E,7R,8R,9S,10S,11R,13E,15E,17S,18R)-18-[(1S,2R,3S)-3-[(2R,4R,5S,6R)-4-[[4-O-(Aminocarbonyl)-2,6-dideoxy-β-D-arabino-hexopyranosyl]oxy]tetrahydro-2-hydroxy-5-methyl-6-(1E)-1-propeny
A661-I
Antibiotic A661I
Antibiotic S-45A
Concanamycin A, Streptomyces sp.
Concanamycin A,(3Z,5E,7R,8R,9S,10S,11R,13E,15E,17S,18R)-18-[(1S,2R,3S)-3-[(2R,4R,5S,6R)-4-[[4-O-(Aminocarbonyl)-2,6-dideoxy-β-D-arabino-hexopyranosyl]oxy]tetrahydro-2-hydroxy-5-methyl-6-(1E)-1-propenyl-2H-pyran-2-yl]-2-hydroxy-1-methylbutyl]-9-ethyl-8,10-
S-45A
NSC 674620
Antibiotic X 4357B
X 4357B
Concanamycin
Concanamycin A

MDL Number

MFCD00210037

FAQ

What is Concanamycin A (CAS: 80890-47-7)?

Concanamycin A is a cyclic lipopeptide antibiotic produced by the soil actinomycete Streptomyces noursei. It has a molecular weight of approximately 1400 Da and a chemical formula of C53H90N6O15. This compound exhibits antifungal and antibacterial properties and is used in research for studying ion transport mechanisms in cells.

What are the main uses of Concanamycin A (CAS: 80890-47-7)?

Concanamycin A is primarily used in pharmaceutical and research settings. It serves as a tool for studying ion transport and signaling pathways in cells, particularly those involving calcium, potassium, and sodium channels. Additionally, it has potential applications in the development of new antibiotics.

Is Concanamycin A (CAS: 80890-47-7) safe?

Concanamycin A is generally considered safe when used under controlled laboratory conditions. However, it should be handled with caution due to its potential for cytotoxicity and mutagenicity. Proper protective measures, including gloves and lab coats, and adherence to safety protocols are essential.

How should Concanamycin A (CAS: 80890-47-7) be stored?

Concanamycin A should be stored in a cool, dry place away from direct sunlight and heat sources. It should be kept in a tightly sealed container to prevent degradation. Optimal storage conditions are at 2-8°C (refrigerated) to maintain its stability and potency.