N-[(4-Hydroxy-1-methyl-7-phenoxy-3-isoquinolinyl)carbonyl]glycine | CAS No. 808118-40-3

N-[(4-Hydroxy-1-methyl-7-phenoxy-3-isoquinolinyl)carbonyl]glycine

Basic Information

CAS Number

808118-40-3

Molecular Formula

C19H16N2O5

Molecular Weight

352.35 g/mol

AD

Basic Physical Properties

Boiling Point

684.3±55.0°C at 760 mmHg

Density

1.389

OC(=O)CNC(=O)c1nc(C)c2c(c1O)ccc(c2)Oc1ccccc1

InChI

InChI=1S/C19H16N2O5/c1-11-15-9-13(26-12-5-3-2-4-6-12)7-8-14(15)18(24)17(21-11)19(25)20-10-16(22)23/h2-9,24H,10H2,1H3,(H,20,25)(H,22,23)

InChIKey

YOZBGTLTNGAVFU-UHFFFAOYSA-N

LogP

2.855520000000001

Topological Polar Surface Area

108.75000000000001 Ų

Hydrogen Bond Donor/Acceptor

3 / 7

Safety Information

View Safety Information

Hazard Statement

H302 Harmful if swallowed
Acute toxicity, oral
H315 Causes skin irritation
Skin corrosion/irritation
H319 Causes serious eye irritation
Serious eye damage/eye irritation
H335 May cause respiratory irritation
Specific target organ toxicity, single exposure; Respiratory tract irritation

Synonyms & References

English

  • Glycine, N-[(4-hydroxy-1-methyl-7-phenoxy-3-isoquinolinyl)carbonyl]-
  • FG-4592
  • N-[(4-Hydroxy-1-methyl-7-phenoxy-3-isoquinolinyl)carbonyl]glycine
  • 2-[(4-hydroxy-1-methyl-7-phenoxyisoquinoline-3-carbonyl)amino]acetic acid
  • FG4592
  • Roxadustat
  • Roxadustat (FG-4592)
  • (((4-Hydroxy-1-methyl-7-phenoxyisoquinolin-3-yl)carbonyl)amino)acetic acid
  • 2-(4-HYDROXY-1-METHYL-7-PHENOXYISOQUINOLINE-3-CARBOXAMIDO)ACETIC ACID
  • Glycine,N-[(4-hydroxy-1-methyl-7-phenoxy-3-isoquinolinyl)carbonyl]
  • (4-hydroxy-1-methyl-7-phenoxyisoquinoline-3-carbonyl)glycine

MDL Number

MFCD20040519

FAQ

What is N-[(4-Hydroxy-1-methyl-7-phenoxy-3-isoquinolinyl)carbonyl]glycine (CAS: 808118-40-3)?

N-[(4-Hydroxy-1-methyl-7-phenoxy-3-isoquinolinyl)carbonyl]glycine is a chemical compound with the CAS number 808118-40-3. It is a derivative of glycine, featuring a complex structure with a 3-isoquinolinyl group substituted with hydroxy, methyl, and phenoxy functionalities. This compound is known for its potential pharmacological activity and is often studied in drug development contexts.

What are the main uses of N-[(4-Hydroxy-1-methyl-7-phenoxy-3-isoquinolinyl)carbonyl]glycine (CAS: 808118-40-3)?

N-[(4-Hydroxy-1-methyl-7-phenoxy-3-isoquinolinyl)carbonyl]glycine (CAS: 808118-40-3) is primarily used in pharmaceutical research as a potential therapeutic agent. It may exhibit biological activity relevant to drug development, particularly in the context of neuropharmacology and anti-inflammatory studies. Its unique molecular structure also makes it a useful compound in chemical synthesis and academic research.

Is N-[(4-Hydroxy-1-methyl-7-phenoxy-3-isoquinolinyl)carbonyl]glycine (CAS: 808118-40-3) safe?

The safety of N-[(4-Hydroxy-1-methyl-7-phenoxy-3-isoquinolinyl)carbonyl]glycine (CAS: 808118-40-3) depends on its specific application and exposure conditions. As a research compound, it is generally handled under controlled laboratory environments. Safety protocols should include proper personal protective equipment (PPE) and adherence to standard chemical safety practices to minimize risks during handling and use.

How should N-[(4-Hydroxy-1-methyl-7-phenoxy-3-isoquinolinyl)carbonyl]glycine (CAS: 808118-40-3) be stored?

N-[(4-Hydroxy-1-methyl-7-phenoxy-3-isoquinolinyl)carbonyl]glycine (CAS: 808118-40-3) should be stored in a cool, dry, and dark place to maintain its stability. It is recommended to keep it in a sealed container away from moisture and light exposure. Storage conditions should also ensure it is kept in a well-ventilated area and protected from potential contaminants to preserve its chemical integrity.

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